Term
What can account for both the diversity and uniformity observed among living organisms on earth? |
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Definition
descent with modification |
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elements have ___ type of atom molecules have ___ type of atom compounds have ___ type of atom |
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Definition
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Definition
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Definition
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Definition
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number of protons in the atom |
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Mass number =
Atomic mass = |
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Definition
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Term
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Definition
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the outermost shell is called the |
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Definition
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Term
a ____ bond is the sharing of a pair of valence electrons by two atoms. |
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Definition
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Term
_____ bonding is the electrostatic force of attraction between positively and negatively charged ions.
electrons are transferred from one atom to another |
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Definition
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Term
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Definition
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Term
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Definition
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is a measure of the attraction an atom involved in a bond has for the electrons of the bond. |
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Definition
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Term
When two atoms bonded by a covalent bond have the same electronegativity the electrons will be equally shared. This is called ________ covalent bonding |
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Definition
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Term
Covalent bonds with unequal electron sharing are called _______ covalent bonds. |
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Definition
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Term
2 examples of intramolecular forces of attraction |
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Definition
Van der Waals and hydrogen bonding |
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Term
________ are attractions between molecules that are close together as a result of these charges
are a result of electrostatic attraction between temporary dipoles (area of charge separation) and caused by movement of electrons in atoms and molecules. |
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Definition
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Term
Weak chemical bonds reinforce ____ of large molecules and help molecules_____ |
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Definition
shapes; adhere to each other |
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Term
is reached when the forward and reverse reaction rates are equal. |
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Definition
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Term
is water polar or non polar? |
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Definition
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Term
water molecules form ____ bonds with each other |
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Definition
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Term
4 water properties that facilitate live environment |
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Definition
Cohesive behavior Ability to moderate temperature Expansion upon freezing Versatility as a solvent |
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Term
is a measure of how hard it is to break the surface of a liquid |
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Definition
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Term
water's specific heat is very |
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Definition
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Term
________ is the amount of heat that must be absorbed (or lost) for 1 gram of a substance to change its temperature by 1o C. |
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Definition
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Term
Heat is________when hydrogen bonds break Heat is _______ when hydrogen bonds form |
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Definition
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Term
ice is ____ dense than water |
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Definition
less due to stability of hydrogen bonds |
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Term
is a liquid that is a homogeneous mixture of substances |
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Definition
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Term
When an ionic compound is dissolved in water, each ion is surrounded by a sphere of water molecules called a |
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Definition
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Term
stable suspension of fine particles in a liquid |
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Definition
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Term
chemical reactions depend on |
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Definition
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Term
The more H+ ions there are in a solution, the more ____ it is. |
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Definition
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Term
are substances that minimize changes in concentrations of H+ and OH– in a solution |
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Definition
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Term
organic means ____ typically also have ___ |
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Definition
having carbon in the compounds... usually have hydrogen too |
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Term
the idea that carbon-hydrogen compounds arise only in organisms. LATER DISPROVED |
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Definition
vitalism...later disproved |
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Term
the view that all natural phenomena are governed by physical and chemical laws |
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Definition
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Term
determines the kinds and number of bonds an atom will form with other atoms |
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Definition
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Term
form the skeletons of most organic molecules |
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Definition
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Term
are organic molecules consisting of only carbon and hydrogen |
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Definition
hydrocarbons
THEYRE NON POLAR, reactions release a LOT of energy |
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Term
are compounds with the same molecular formula but different structures and properties: |
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Definition
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Term
have different covalent arrangements of their atoms |
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Definition
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Term
____ isomers have the same covalent arrangements but differ in spatial arrangements around a double bond |
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Definition
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Term
are isomers that are mirror images of each other |
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Definition
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Term
are the components of organic molecules that are most commonly involved in chemical reactions
The # and arrangement of these give each molecule its unique properties |
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Definition
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Term
are large molecules composed of thousands of covalently connected atoms |
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Definition
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Term
fats are built from subunits via |
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Definition
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Term
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Definition
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Term
Joining together two monomers by removing a molecule of water
repeat to make longer |
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Definition
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Term
Breaking apart monomers by adding water
repeat to break bond |
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Definition
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Term
the two disaccharides from carbs |
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Definition
sucrose- fructose & glucose & lactose- galactose and glucose |
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Term
two types of polysaccharides are |
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Definition
cellulose
starch & glycogen |
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Term
monosaccharides are classified by |
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Definition
location of carbonyl group |
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Term
in aqueous solutions many sugars form |
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Definition
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Term
glycosidic linkage has what type of bond? |
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Definition
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Term
storage polysaccharide in animals is
for plants its |
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Definition
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Term
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Definition
amylose-unbranched 4
amylopectin-branched 6 |
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Term
Polymers with alpha glucose are |
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Definition
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Term
Cellulose in human food passes through the digestive tract as ________ |
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Definition
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Term
a structural polysaccharide that provides structural support for the cell walls of many fungi
nitrogen group attached to glucose |
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Definition
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Term
the unifying feature of lipids is they have: |
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Definition
no/little affinity for water |
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Term
3 most biologically important lipids are: |
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Definition
fats, phospholipids, steroids |
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Term
fats are constructed from two types of smaller molecules: |
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Definition
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Term
in a phospholipid...The two fatty acid tails are _____, but the phosphate group and its attachments form a _____ head |
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Definition
hydrophobic....hydrophilic |
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Term
phospholipids and cholesterol are very important in _____ |
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Definition
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Term
are lipids characterized by a carbon skeleton consisting of four fused rings |
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Definition
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Term
the bond between two amino acids is a ____ bond |
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Definition
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Term
polymers built from the combinations of the 20 amino acids |
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Definition
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Term
are a type of protein that acts as a catalyst to speed up chemical reactions |
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Definition
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Term
there are ___ different types of amino acids |
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Definition
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Term
the order of the amino acids that form the polypeptide affects how the protein |
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Definition
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Term
tertiary structure is determined by |
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Definition
interactions among various side chains (R groups) |
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Term
primary structure is based on the |
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Definition
the sequence of amino acids in the polypeptide chain |
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Term
secondary structure is due to the ___ bonds |
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Definition
hydrogen. between repeating constituents of the polypeptide backbone |
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Term
4 types of interactions in tertiary structure are |
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Definition
disulfide bridges, van der waals, hydrophobic interactions and some hydrogen bonding |
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Term
is a fibrous protein consisting of three polypeptides coiled like a rope |
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Definition
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Term
is a globular protein consisting of four polypeptides: two alpha and two beta chains |
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Definition
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Term
the loss of a protein's native structure is called |
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Definition
denaturation
which makes it biologically inactive |
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Term
protein molecules that assist the proper folding of other proteins |
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Definition
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Term
Alzheimer’s, Parkinson’s mad cow disease Lou Gehrig’s disease
can all be caused by _____ proteins |
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Definition
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Term
___ directs the synthesis of mRNA |
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Definition
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Term
_____ RNA controls protein synthesis |
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Definition
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Term
Each _____ consists of a nitrogenous base, a pentose sugar, and a phosphate group |
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Definition
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Term
a ____ has only a nitrogenous base and a pentose sugar |
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Definition
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Term
Nucleotide: uracil instead of thymine Single stranded ribose v deoxy-ribose
these are characteristics of |
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Definition
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Term
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Definition
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Term
the bonds holding together a base pair of DNA are ___ bonds |
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Definition
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Term
carries energy stored in bonds between phosphate groups |
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Definition
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Term
_______ carry chemical signals between molecule |
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Definition
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Term
3 types of cellular life: |
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Definition
archaea, bacteria, and eukaryota |
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Term
aqueous droplet surrounded by a membrane |
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Definition
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Term
Lipids added to water can spontaneously form |
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Definition
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Term
4 types of life in the domain eukarya: |
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Definition
protists, fungi, plantae, animalia |
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Term
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Definition
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Term
Cell (plasma) membrane Semi-fluid interior = cytoplasm (aka cytosol) DNA organized into chromosome/s Ribosomes
THESE 4 CHARACTERISTICS ARE COMMON TO: |
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Definition
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Term
Cell (plasma) membrane Semi-fluid interior = cytoplasm (aka cytosol) DNA organized into chromosome/s Ribosomes
THESE 4 CHARACTERISTICS ARE COMMON TO: |
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Definition
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Term
3 main differences in eukaryotes that aren't in prokaryotes: |
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Definition
membrane bound organelles and TRUE nucleus, compartmentalized membranes! |
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Term
in prokaryotes, DNA is located in the unbound region called hte |
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Definition
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Term
bacteria cell walls are made of |
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Definition
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Term
a difference between archaea and bacteria is that archaea includes |
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Definition
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Term
Exchange of oxygen, nutrients, and wastes occurs at the |
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Definition
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Term
_____ cells have a greater surface area relative to volume |
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Definition
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Term
The_____ the surface to volume ratio, the less effective is exchange of gases & nutrients per unit of volume |
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Definition
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Term
To get big, increase ______ not cell size |
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Definition
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Term
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Definition
you to see cells dead OR ALIVE |
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Term
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Definition
you to see cells dead OR ALIVE |
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Term
TEM & SEM are both in the type of ___ microscopy |
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Definition
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Term
_____ Separates cellular components based on size and density |
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Definition
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Term
chloroplasts (plastids), central vacuoles, cell wall, plasmodesmata
these are only found in ___ cells |
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Definition
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Term
lysosomes, centrosomes & centrioles, flagella
these are only found in |
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Definition
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Term
The general structure of a biological membrane is a double layer of _______ |
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Definition
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Term
________ use the information from the DNA to make proteins |
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Definition
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Term
_____ regulate the entry and exit of molecules from the nucleus |
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Definition
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Term
The shape of the nucleus is maintained by the _____ which is composed of protein filaments |
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Definition
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Term
In the nucleus, DNA and proteins form genetic material called ____ which condenses to make chromosomes |
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Definition
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Term
the site of ribosomal RNA synthesis is the |
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Definition
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Term
In the cytosol (free ribosomes) On the outside of the endoplasmic reticulum or the nuclear envelope (bound ribosomes)
these are the two places of _____ synthesis |
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Definition
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Term
Nuclear envelope Endoplasmic reticulum (ER) Golgi apparatus Lysosomes Vacuoles Plasma membrane These are the 6 components of the _________
These components are either continuous or connected via transfer by |
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Definition
endomembrane system; vesicles |
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Term
Nuclear envelope Endoplasmic reticulum (ER) Golgi apparatus Lysosomes Vacuoles Plasma membrane These are the 6 components of the _________
These components are either continuous or connected via transfer by |
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Definition
endomembrane system; vesicles |
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Term
Nuclear envelope Endoplasmic reticulum (ER) Golgi apparatus Lysosomes Vacuoles Plasma membrane These are the 6 components of the _________ |
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Definition
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Term
The ER membrane is continuous with the |
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Definition
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Term
different from the ROUGH ER the smooth ER has NO |
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Definition
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Term
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Definition
metabolizes carbs, synthesizes lipids & stores calcium |
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Term
Polypeptide often combined with carbohydrate is called a |
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Definition
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Term
transport vesicles leave Rough ER then travel to the |
|
Definition
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Term
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Definition
membranes for other parts of the cell |
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Term
flattened membranous sacs are called |
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Definition
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Term
Further modification of the glyco-proteins received from the ER Modification of phospholipids Manufactures certain macromolecules Sorts and packages materials into transport vesicles
ALL OF THESE ARE FUNCTIONS OF THE |
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Definition
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Term
cis face is the ___ side of the golgi |
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Definition
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Term
Last step before protein leaves golgi = |
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Definition
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Term
Hydrolytic enzymes (lyzozymes) made in RER, travel through Golgi, and are packaged as _____ for use in cell |
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Definition
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Term
a membranous sac of hydrolytic enzymes that can digest all macromolecules |
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Definition
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Term
food vacuoles are formed when a cell engulfs another via ______ |
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Definition
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Term
|
Definition
organic compounds and water |
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Term
contractile vacuoles pump out ____ |
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Definition
excess water out of the cells |
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Term
mitochondria and chloroplasts have 3 things in common: |
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Definition
own circular DNA, have proteins made of free ribosomes, and both have a double membrane |
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Term
mitochondria is necessary for ____ reactions |
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Definition
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Term
mitochondria extracts ___ |
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Definition
energy from food molecules |
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Term
chloroplasts are members of the family of ___ |
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Definition
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Term
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Definition
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Term
the inner membrane of a ______ is usually not visible when viewed through an electron micrograph |
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Definition
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Term
Specialized metabolic compartments bounded by a single membrane Detoxify harmful compounds (alcohol) by converting to hydrogen peroxide (H2O2) |
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Definition
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Term
Network of fibers extending throughout the cytoplasm Organizes the cell’s structures and activities Anchors many organelles |
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Definition
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Term
Shaping the cell – resist compression Guiding movement of organelles Separating chromosomes during cell division Major components of: Centrioles & Centrosomes Flagella Cilia |
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Definition
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Term
The _______ is a microtubule-organizing center. |
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Definition
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Term
centrioles have ____ sets of microtubules in triplets |
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Definition
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Term
Microtubules are responsible for the beating of ___ & ____ |
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Definition
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Term
cilia and flagella are anchored by a ____ |
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Definition
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Term
there are short and many ____
there are long and few ____ |
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Definition
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Term
A motor protein called ______ drives the bending movements of a cilium or flagellum |
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Definition
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Term
muscle contraction, cell division (form cleavage furrow), cell motility (pseudopodia), tension bearing in maintenance of cell shape
these are the functions of |
|
Definition
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Term
microvilli of intestinal cells are made from bundles of |
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Definition
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Term
Microfilaments that function in cellular motility contain the protein _____ in addition to actin |
|
Definition
myosin
myosin in my microfil |
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Term
forms nuclear lamina, anchors nucleus and other organelles are more permanent parts of the cytoskeleton than the other two classes these are functions of the |
|
Definition
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Term
Non-motile Functions in signal reception Important in kidney, brain function and embryonic development. Defect in it --> polycystic kidney disease |
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Definition
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Term
gram negative type of bacterial cell wall has a ___ complex structure than gram positive |
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Definition
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Term
thin layer between primary walls of adjacent cells (pectin) |
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Definition
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Term
allow passage of water and small solutes (and sometimes proteins and RNA) from cell to cell |
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Definition
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|
Term
THE ECM for animals is made up of |
|
Definition
collagen, proteoglycan and fibronectin |
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Term
ECM proteins bind to receptor proteins in the plasma membrane called |
|
Definition
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Term
Support and shape tissues Movement – tracks for migrating cells during embryonic development Affect signaling within the cell Regulate: Secreted proteins & Immune response
functions of the |
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Definition
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|
Term
(anchoring junctions) fasten cells together into strong sheets |
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Definition
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Term
(communicating junctions) provide cytoplasmic channels between adjacent cells |
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Definition
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Term
membranes of neighboring cells are pressed together, preventing leakage of extracellular fluid
these are called ___ junctions |
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Definition
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Term
a problem with the Danellie fluid mosaic model is that: The membrane proteins are amphipathic which means |
|
Definition
they have both hydrophilic and hydrophobic regions |
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|
Term
is a specialized preparation technique that splits a membrane along the middle of the phospholipid bilayer |
|
Definition
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|
Term
Membrane fluidity depends on what types of |
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Definition
fatty acids compose the hydrophobic tails of the phospholipids |
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Term
membrane fluidity is ____ dependent |
|
Definition
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|
Term
for membrane fluidity: At warm temperatures (such as 37°C), ______ restrains movement of phospholipids.
At cool temperatures, it maintains fluidity by preventing tight packing |
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Definition
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Term
davson and danellie proposed the ____ model which was later disproved |
|
Definition
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Term
for the fluid mosaic model ________ proposed that the membrane is a mosaic of proteins dispersed within the bilayer, with only the hydrophilic regions exposed to water. |
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Definition
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Term
_____ proteins are bound to the surface of the membrane |
|
Definition
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Term
_______ proteins penetrate the hydrophobic core. Some extend through to outside and inside of cell. Some extend only partway into the membrane on cross the entire membrane |
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Definition
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Term
The asymmetrical distribution of proteins, lipids, and associated carbohydrates in the plasma membrane is determined when the membrane is built by _____ |
|
Definition
the ER and Golgi apparatus |
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Term
_______ on the external side of the plasma membrane vary among species, individuals, and even cell types in an individual |
|
Definition
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Term
_____ molecules, such as hydrocarbons, O2 and CO2 can dissolve in the lipid bilayer and pass through the membrane rapidly |
|
Definition
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Term
______ such as sugars and ions, do not cross the lipid membrane easily |
|
Definition
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Term
-never a direct connection between outside and in. -Change shape which allows it to open first to one side and then the other
what type of transport protein is this? |
|
Definition
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|
Term
two types of transport proteins are: |
|
Definition
carrier & channel proteins |
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Term
– form a water filled pore Ions (Na+ and K+) pass through channels Water also uses these called aquaphorins
what type of transport protein is this? |
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Definition
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Term
No energy needed High to low concentration Examples diffusion, osmosis
this is describing ____ transport |
|
Definition
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Term
Energy needed Low to high or high to low concentration Examples: Na+-K+ pump, H+ pump
these describe ___ transport |
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Definition
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|
Term
is the tendency for molecules to spread out evenly into the available space |
|
Definition
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|
Term
Factors that affect ___ diffusion : Molecule size Temperature Medium Volatility |
|
Definition
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|
Term
is the diffusion of water across a selectively permeable membrane
low to high solute concentration |
|
Definition
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|
Term
_____ is the ability of a solution to cause a cell to gain or lose water |
|
Definition
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|
Term
Solute concentration is the same as that inside the cell; no net water movement across the plasma membrane
this describes a ____ solution |
|
Definition
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|
Term
Solute concentration is greater than that inside the cell; cell loses water in a _____ solution |
|
Definition
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|
Term
Solute concentration is less than that inside the cell; cell gains water in a ____ solution |
|
Definition
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|
Term
Diffusion requires a _______ if the membrane is not permeable to the solute |
|
Definition
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Term
Facilitated diffusion is still ____ because the solute moves down its concentration gradient |
|
Definition
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|
Term
____ transport moves substances against their concentration gradient |
|
Definition
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Term
Concentration gradient established by Na+/K+ pump favors movement of ______ into cell. Can be used to co-transport other solutes against their concentration gradient |
|
Definition
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|
Term
primary active transport uses __ as energy |
|
Definition
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|
Term
The ____ pump is the main electrogenic pump in plants, fungi, & bacteria |
|
Definition
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|
Term
Phagocytosis Exocytosis Endocytosis These processes require energy
these are describing traits/processes of ____ transport |
|
Definition
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|
Term
_____ is the voltage difference across a membrane Inside of cell is negative compared to the outside Usually about -70 mV |
|
Definition
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|
Term
____ can power: Secondary active transport Signals in neurons (action potentials) |
|
Definition
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|
Term
is the sequence of events that leads to the cell’s response to the signal |
|
Definition
signal transduction pathway |
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|
Term
___ is the conversion of the external signal to internal signals or reactions within the cell |
|
Definition
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|
Term
___ determines whether the cell is a target for a given ligand |
|
Definition
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|
Term
Binding of ____ to receptor leads to a chemical change inside the cell |
|
Definition
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|
Term
Cell junctions that directly connect the cytoplasm of adjacent cells direct cell to cell contact, or cell-cell recognition
these are examples of ___ signaling |
|
Definition
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|
Term
the two types of long distance signaling are: |
|
Definition
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|
Term
____ : produce hormones that are carried by the circulatory system to remote locations within the organism.
this is a type of long distance signaling |
|
Definition
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|
Term
a type of long distance signaling where: Electrical transmission along neurons |
|
Definition
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|
Term
a signal molecule is also called a |
|
Definition
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|
Term
_____ receptor= Larger or polar signals. The peptide hormone insulin is hydrophilic and cannot pass through the cell membrane. The insulin receptor is a transmembrane protein with an extracellular domain |
|
Definition
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|
Term
____ receptors=
Small or nonpolar signals. The steroid hormone estrogen is lipid soluble and can pass through the cell membrane |
|
Definition
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|
Term
membrane bound receptors bind |
|
Definition
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|
Term
cytoplasmic receptors bind _____ signals |
|
Definition
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|
Term
receptors can be in these three places: |
|
Definition
the nucleus, the cytoplasm (for lipophylic) or on the cell membrane |
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|
Term
1. Ion channels 2. G protein coupled receptors 3. Receptor enzymes Example receptor tyrosine kinase
these are the 3 MAIN types of |
|
Definition
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|
Term
____ channels are Ligand gated Voltage gated Mechanically gated |
|
Definition
ion
type of membrane receptor |
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|
Term
= enzyme that catalyzes phosphorylation |
|
Definition
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|
Term
In many pathways, the signal is transmitted by a cascade of__________________ |
|
Definition
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|
Term
Protein phosphatases remove the phosphates from proteins, a process called _____________ |
|
Definition
dephosphoylation by hydrolysis |
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|
Term
direct Change initiated by membrane receptor/ligand is via |
|
Definition
|
|
Term
signal transduction pathways involve involve activation of proteins within the cell by |
|
Definition
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|
Term
cAMP Ca2+ IP3 (diffuses through cytoplasm) and DAG (lipid soluble - remains associated with membrane)
these 3 are examples of _____ in a signal transduction pathway |
|
Definition
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|
Term
When it’s time to stop the signal cascade, enzymes break down _____ |
|
Definition
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|
Term
IP3 acts on __________ to release Ca2+ which then also acts as a second messenger (even though it’s #3!)
in signal transduction pathways |
|
Definition
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|
Term
Protein kinase activates (phosphorylates) enzyme while _______________ inactivates (dephosphorylates) |
|
Definition
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|
Term
Adenylyl cylase forms cAMP while ________________ inactivates cAMP |
|
Definition
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|
Term
the capacity to cause change (do work) |
|
Definition
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|
Term
________ pathways consume energy to build complex molecules from simpler ones
The synthesis of protein from Amino acids |
|
Definition
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|
Term
release energy by breaking down complex molecules into simpler compounds
Cellular respiration, the breakdown of glucose in the presence of oxygen, |
|
Definition
|
|
Term
|
Definition
Energy is neither created nor destroyed. |
|
|
Term
every energy transfer increases |
|
Definition
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|
Term
When energy is converted from one form to another, some of that energy becomes unavailable to do work.
this is the |
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
If ΔG is negative, free energy is _______ |
|
Definition
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|
Term
No outside energy input needed = __________ process |
|
Definition
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|
Term
During a spontaneous change, free energy _____ and the stability of a system ____ |
|
Definition
free energy decreases and stability increases |
|
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Term
A process is spontaneous and can perform work only when it is moving toward ____ |
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only ____ reactions can be energy coupled |
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ATP drives____ reactions by phosphorylation, transferring a phosphate group to some other molecule, such as a reactant |
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making ATP is a ____ reaction |
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Hydrolysis of ATP yields_____ |
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Activation energy changes the reactants into unstable forms with higher free energy which are called |
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transition state intermediates |
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substrate molecules bind at the |
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the _____ of the enzyme determines the _____ |
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3D shape determines which molecules they interact with |
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Enzymes ____ the energy barrier for reactions. |
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Enzymes can temporarily add ______ to substrates. |
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Binding of substrate to the active site depends on ____ bonds, attraction and repulsion of electrically charged groups, and hydrophobic interactions. |
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Binding of substrate to the active site depends on ____ bonds, attraction and repulsion of electrically charged groups, and hydrophobic interactions. |
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Small carbon-containing molecules; not bound permanently to enzymes are called |
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The more substrate, the ________ the reaction |
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Naturally occurring _______ are important in regulating metabolism. |
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Inhibitor covalently bonds to side chains in the active site—permanently inactivates the enzyme.
this is called ____ inhibition |
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An effector molecule binds to a regulatory subunit, inducing the enzyme to change its shape.
this is called ____ regulation |
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In ___________ inhibition, the end product of a metabolic pathway shuts down the pathway |
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if there are a lot of bacteria then ____ can occur |
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