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The active site can lower an EA barrier by |
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Orienting substrates correctly Straining substrate bonds Providing a favorable microenvironment Covalently bonding to the substrate |
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the totality of an organism chemical reactions , it is the emergent propoerty of life that arisese from interactions between molcules |
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begins with a specific moleule and ends with a products |
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release energy by breaking down complex molecules into smaller compounds ex. cellular respiration breaks down glucose in the presense fo oxygen |
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consume energy to build complex molecules from simpler ones |
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the study of how organisms manage thier energy sources |
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the capacity to cause change , it exsist in various forms |
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what are the forms of energy |
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kinetic- associated with motion heat-kinetic energy associated with random movement of atoms or molecules potential -energy that matter possess because of its location or structure |
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the study of energy transformations |
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what is the first law of thermodynamics |
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The energy of the universe is constant ENERGY CAN BE TRANSFORMED OR TRANSFERED BUT NOT CREATED OR DESTROYED. |
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What is the second law of thermodynamics |
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every energy transfer or transformation increases entropy(disorder) of the universe |
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what are spontaneous processes |
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ones that occur without energy input , they can happen very quickly or very slowly |
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what does the free energy change of reactions tell us |
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whether or not the reactions occurs spontaneously |
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the energy that can do work when temp and pressure are uniformed , only negative deltaG is spontaneous |
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a state of maximum stabilty |
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what is an exergonic reaction |
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proceeds with a net release of free energy and is spontaneous |
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what is an energonic reaction |
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absorbs free energy from its surroundinds and is nonspontaneous |
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what kinds of work does a cell do |
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chemical transport mechanical |
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the use of an exergonic process to drive and endergonic one |
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this funtions as the cells energy shuttle , what is it |
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ribose , adenine and three phosphate groups |
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what are the 3 types of cellular work powered by |
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a chemical agent that speeds up a reactions without being consumed by the reaction. |
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what is activation energy |
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teh energy needed to start a chemical reaction |
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hwo to enzymes catalyze reactions |
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Definition
by lowering the Ea barrier |
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The reactant that an enzyme acts on is called the enzyme’s |
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what forms when enzymes bind to substrates |
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enzyme -substrate complex |
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what is an enzymes active site |
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the region ont he enzyme where the substrate binds |
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what does induced fit of a substrate bring about |
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of a substrate brings chemical groups of the active site into positions that enhance their ability to catalyze the reaction |
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non protien enzymes helpers that may be inorganic |
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this binds to another part of an enzyme causing the enzyme to change shape and makes the active site less effective |
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non competative inhibitor |
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when does allosteric regulation occur |
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when a regulatory molecule binds to a protien at one site and affatcs the protien function at another site |
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what are the most allosterically regulated enzymes made from |
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what does the binding of an activator and inhibitors do |
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The binding of an activator stabilizes the active form of the enzyme The binding of an inhibitor stabilizes the inactive form of the enzyme |
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Cooperativity is a form of allosteric regulation that can amplify enzyme activity One substrate molecule primes an enzyme to act on additional substrate molecules more readily Cooperativity is allosteric because binding by a substrate to one active site affects catalysis in a different active site |
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the end product of a metabolic pathway shuts down the pathway , prevents a cell from wasting chemical resources by synthesising more products than needed. |
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