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Bio Chapters 4-6
Protein/ DNA synthesis
40
Biology
Undergraduate 2
10/14/2009

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Term
alpha helix
Definition
common folding pattern that is a single helix strand held together by charge
Term
beta sheet
Definition
common folding pattern that the arrows will point towards the c-terminus
Term
antibody
Definition
the body's defense mechanism that is created after encountering a pathogen
Term
antigen
Definition
pathogen or foreign invader in the body that can cause harm
Term
binding site
Definition
site on an antibody that is specific to the shape of the antigen
Term
hydrolase
Definition
general term for enzymes that catalyze a hydrolic cleavage reaction
Term
nuclease
Definition
breaks down nucleic acids by hydolyzing bonds between nucleotides
Term
protease
Definition
breaks down proteins by hydrolyzing peptide bonds between amino acids
Term
synthase
Definition
general name for enzymes that syynthesize molecules in anabolic reactions by condensing two molecules together
Term
isomerase
Definition
catalyzes the rearrangement of bonds within a single molecule
Term
polymerase
Definition
catalyzes polymerzation reactions such as synthesis of DNA and RNA
Term
kinase
Definition
catalyzes the addition of phosphate groups to molecules
Term
protein kinase
Definition
attach phosphate groups to proteins
Term
phosphatase
Definition
catalyzes the hydrolytic removal of a phosphate group from a molecule
Term
oxido-recuctase
Definition
general name for enzymes that catalyze reactions in which one molecule is oxidized while the other is reduced
Term
ATPase
Definition
hydrolyzes ATP
Term
telomeres
Definition
the ending points on the chromosomes
Term
nucleolus
Definition
place within the nucleus that contains the chromosomes and disappears during mitosis
Term
chromatin
Definition
a single strand of a chromosome that contains DNA and the genetic information
Term
Cell Cycle
Definition
IPMAT (Interphase, prophase, metaphase, anaphase, telaphase)
Term
Central Dogma of Biology
Definition
A cell can only come from another cell that has replicated itself
Term
Disulfide bond
Definition
an interchain bond that is commonly found stabilizing extracellular proteins
Term
conformation
Definition
different structural shapes of a molecule that can easily be molded into another shape without changing the molecular structure to reduce energy
Term
helix
Definition
the shape of DNA, a ribbon that is similar to a spiral staircase
Term
coiled-coil
Definition
coiling itself so that the hydrophobic nonpolar regions are on the inside of the molecule and the polar side of the molecule is located on the outside of molecule
Term
histone
Definition
the core component that has the DNA wind around it to become more compact
Term
nucleosome
Definition
200 nucleotide pairs of DNA, length= the distance from one histone to the next
Term
heterochromatin
Definition
tichtly packed genes that dont need to be used often
Term
euchromatin
Definition
loosely packed highly expressive genes
Term
phosphodiester bond
Definition
binds the sugar to the diphosphate group
Term
Western Blot
Definition
run DNA gel and put it on a membrane with protein
Term
ampathatic
Definition
one polar end, one non-polar side
Term
dimer
Definition
2 pieces together in order to function
Term
ligand
Definition
any molecule that binds to the protein (shape is important)
Term
Cyclic AMP
Definition
puzzle piece that fits perfectly due to shape and charge
Term
electrostatic attraction
Definition
negative-positive attraction
Term
Van der Waals attraction
Definition
every atom has different size, and they determine where they no longer repel, where there is a slight attraction due to the fact that e- are constantly moving
Term
karyotype
Definition
display of the full set of chromosomes
Term
gene
Definition
information for a specific chemical or physical appearance/function
Term
autosomal
Definition
non-sex chromosomes
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