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Bio 7
Membrane Structure and Function
63
Biology
Undergraduate 1
09/25/2012

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Term
Selective Permeability
Definition
The plasma membrane's allowance of some substances to pass more easily through it than others.
Term
Cellular membranes are mostly made of...
Definition
Lipids and proteins.
Term
Phosphplipid
Definition
The amphipathic lipid with a hydrophilic phosphate head, and hydrophobic hydrocarbon chains of fatty acids in the form of two tails, which makes up the bilayer
Term
Amphipathic
Definition
When a molecule has both a hydrophobic region and a hydrophillic region.
Term
Fluid mosaic model
Definition
The model of how the membrane is a fluid structure with a "mosaic" of various proteins and phospholipids.
Term
Integral Proteins
Definition
Proteins that penetrate the whole bilayer with varying hydrophilic and hydrophobic regions.
Term
Two major populations of membrane proteins:
Definition
Integral and Peripheral
Term
Peripheral Proteins
Definition
Proteins loosely bound to the surface of the membrane.
Term
Functions of membrane proteins:
Definition
- transport
- enzymes
- cell communication
- physical attachment
Term
Membrane carbohydrates used in cell-cell recognition are..
Definition
Glycoproteins and glycolipids
Term
Glycoproteins and glycolipds are used for:
Definition
- Cell identification
- Immunity (self vs. not-self)
- Embryonic cell sorting
Term
Cell membranes enable...
Definition
internal regulation -- a characteristic of life.
Term
Membranes are both...
Definition
Flexible and stable -- a bit like how bubbles can morph and change, but not break.
Term
All cells have have...
Definition
external plasma membranes, but Eukaryotes also have internal membranes.
Term
Cholesterol helps...
Definition
keep the membrane fluid-like.
Term
What can easily pass the semipermeable membrane?
Definition
hydrophobic, but not hydrophilic particles.
Term
The membrane proteins are:
Definition
integral and peripheral
Term
The simplification of diagrams...
Definition
While proteins looks like globs, they are actually complicated 3-D structures.
Term
Passive transport
Definition
Diffusion of a substance across a membrane with no energy used.
Term
Categories of passive transport
Definition
Diffusion, Facilitated diffusion, osmosis.
Term
Transport proteins
Definition
The proteins that span the membrane that allow hydrophilic substances to pass through the hydrophobic bilayer.
Term
Types of transport proteins
Definition
-- Channel proteins with a hydrohillic channel like a tunnel to pass through.
-- Carrier proteins that hold on to their molecular passengers and change shape in a way that shuttles them across the membrane
Term
Aquaporins
Definition
A type of channel protein for H2O transport.
Term
Diffusion
Definition
the movement of molecules down a concentration gradient until equilibrium is reached.
Term
Concentration gradient
Definition
The region along which the density of a chemical substance increases or decreases.
Term
Examples of diffusion
Definition
C02 in lungs
Drop of dye in water
Milk poured in tea.
Term
All molecules are in...
Definition
constant, random motion, diffusing independently of one another's concentration gradient.
Term
Diffusion rate is influenced by:
Definition
- size of molecules
- concentration gradient
- temperature
- possibly electric or pressure gradients.
Term
True or false: there are only a few types of protein in facilitated diffusion.
Definition
False: Because proteins are specific to the substances they let pass through, cells have many different proteins.
Term
Osmosis
Definition
The diffusion from a low to a high solute concentration across a semi-permeable membrane.
Term
Is osmosis exclusive to water?
Definition
No, but it happens most often with water.
Term
Isotonic
Definition
Where the solute is equal on both sides of a membrane and there is no net movement in or out of the cell.
Term
Hypertonic solution
Definition
When the solution has more solute than the cell and the cell may lose water, shrivel and probably die.
Term
Hypotonic solution
Definition
When the solution has less solute than the cell and the cell takes up water.
Term
Water moves from
Definition
the more dilute solution to the more concentrated solution, or from the more hypotonic solution to the hypertonic solution.
Term
The ideal solution for a blood cell is
Definition
isotonic.
Term
Osmoregulation
Definition
The control of solute concentrations and water balance, especially important in cells without cell walls.
Term
Lysed
Definition
Exploded
Term
Flaccid
Definition
Limp, what happens to a plant cell in an isotonic solution.
Term
Turgid
Definition
Firm, a healthy state for plant cells
Term
Plasmolyzed
Definition
Shriveled, where the plasma membrane pulls away from the wall.
Term
While membranes ______________________, cell walls __________________.
Definition
While membranes need water to swell up, cells walls stay rigid because they are made of cellulose.
Term
The ideal solution for a plant cell is...
Definition
hypotonic.
Term
Diffusion deals with what type of particles?
Definition
Small, nonpolar particles.
Term
Facilitated diffusion deals with what type of particles?
Definition
Large, polar particles.
Term
Why do you not want to drink distilled water when you are dehydrated?
Definition
Your hypertonic cells will lyse from the uptake of water.
Term
Facilitated diffusion
Definition
Passive transport of large, hydrophobic particles aided by proteins
Term
Active transport
Definition
Transportation across a membrane against the concentration gradient, which requires ATP.
Term
ATP
Definition
Cellular energy, which drives transport proteins.
Term
Sodium Potassium Pump (NaK Pump)
Definition
An active protein transport system that exchanges Na ions for K ions against the concentration gradient by oscillating between two shapes for the ion shapes.
Term
What charge does the inside of the cell have?
Definition
A slight negative charge, which creates a concentration gradient into the cell for cations.
Term
All sensory changes are a result of
Definition
ion detection.
Term
Co-transport
Definition
When a protein's active transport of of a solute indirectly drives the active transport of other solutes, like how water pumped up hill can perform work while going back down.
Term
Example of cotransport
Definition
A plant's cells active pumping of H+ ions out of the cell helps create the potential energy outside the cell to pump in other solutes against their gradients.
Term
Exocytosis
Definition
When vesicles fuse with the plasma membrane to transport large macromolecules out of the cell
Term
Endocytosis
Definition
The taking in of particles by forming pocket-like vesicles that pinch into the cell.
Term
Phagocytosis
Definition
A version of endocytosis where a cell engulfs a large particle in a membranous sac; "cellular eating."
Term
Pinocytosis
Definition
A version of endocytosis where a cell "gulps" small particles in tiny membranous vesicles; "cellular drinking."
Term
Receptor-mediated endocytosis
Definition
A version of endocytosis for bulk quantities of specific substances where ligand molecules bind to receptors in the extracellular fluid and are taken into vesicles.
Term
Endocytosis and exocytosis are both...
Definition
Active transport.
Term
The size of a plasma membrane
Definition
~8nm, like 1000th of a cell.
Term
The phospholipid bilayer is comprised of
Definition
phospholipids, cholesterol, proteins, glycoproteins/glycolipids.
Term
Ligand
Definition
Any molecule that binds specifically to a receptor site on another molecule.
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