Term
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Definition
| big changes in chromosomal structure |
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Term
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Definition
affect single base pairs
causes: errors in DNA replication or repair
mutagens: physical or chemical agents that damage DNA
2 types |
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Term
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Definition
replacement of 1 base pair
ex. SNP
possible outcomes in protein coding region |
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Term
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Definition
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Term
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Definition
| changes an aa codon to a stop codon, shortens the protein |
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Term
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Definition
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Term
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Definition
caused by bp insertion or deletion (indel)
-in protein coding region they shift down stream reading frame
-may cause: missense, nonsense mutations |
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Term
| Positive form of Transcription Regulation |
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Definition
transcription requires help due to a weak promoter, one that can't bind RNA pol alone w/out DNA binding proteins called transcription factors
Ex. MyoD specialize as muscle cells |
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Term
| negative form of transcription regulation |
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Definition
blocks transcription of genes whose default is on, for genes with strong promoters
Ex. Trp Operon: genes of 5 enzymes for trp synthesis containing operator and repressor protein |
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Term
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Definition
deflation of specific mRNA's before translation
-caused by miRNA with complementary sequence to target mRNA |
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