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complex, highly organized network of billions of neurons and neuroglia, along with supporting blood vessels and connective tissue. |
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In order of transmission across synapase, from first structure to last: |
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Presynaptic end bulb, synaptic cleft, and postsynaptic neuron. |
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Membrane potential values, from most negative to zero: |
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Resting membrane potential, threshold and depolarized membrane potential. |
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Basic function of the Nervous system |
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1. Sensory 2. Integration (CNS) 3. Motor (PNS) |
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extensive network of neurons found in the walls of organs of digestive tract. Help in digestive |
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*Integretes, processes and correlates different types of incoming sensory information, and out going motor commends. *Scource of thoughts, emotions and memories *most nerve impulses that muscles to contract and glands to secrete, originate in the CNS |
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Peripheral Nervous system |
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Includes all nervous tissue outside the CNS *cranial nerves and their branches *spinal nerves and their branches *ganglia *sensory receptors |
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Sensory (afferent) division |
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madeup of nerve fibers that convey impulses to the CNS from sensory receptors located throughout the body |
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sensory fibers conveying impulses from the skin, skeletal muscles and joints |
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sensory fibers conveying impulses from the visceral organs to the CNS |
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Controls skeletal muscle contractions *consist of the somatic motor neurons from the CNS that conducts impulses to skeletal muscles only *their cells body is located in the CNS *Since the motor responses can be controlled consciously, the actin of this part of the PNS is VOLUNTARY. |
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allows automatic regulation of smooth muscle, cardiac muscles and gland secretions- this occurs at the subconscious level *visceral motor neurons from the CNS that conduct nerve impulses to: *smooth muscle, cardiac muscle, glands, and adipose tissue. *since its motor responses are not normally under conscious control, the actin of the ANS is INVOLUNTARY |
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The brain of the gut. *Consists of neurons in enteric plexuses that extend the entire length of gastrointestinal tract. |
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the excitable nerve cells that transmit electrical signals *similar to muscle cells, neurons also have the property of electrical excitability: the capability to produce action potential or impulses in response to stimuli. |
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supporting cells. *Smaller cells that surround and wrap the more delicate neurons |
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produce the insulting covering called myelin sheaths in the CNS |
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epithelial layer formed by the ependymal cells: plays a role in the production of cerebral spinal fluid |
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produce the insulting covering called the myelin sheaths in the PNS. *Scwann cells shield most PNS axons (myelinated and unmyelinated) from contracting the interstitial fluid. |
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contains a nucleus surrounded by cytoplasm that includes: lysosomes, mitochondria, golgi complex, lipofusion, and Nissl bodies |
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prominent clusters of rough ER * They are the reason why gray matter appears gray |
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clusters of cell bodies in the CNS |
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cluster of cell bodies that lie along the nerves in the peripheral NS |
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bundles of neuron processes in the CNS |
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bundles of neuron processes in the PNS |
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armlike processes extend from the cell body of all neurons *the brain and spinal cord (CNS) contain neuron cell bodies and their processes *The peripheral NS consists mainly of neuron processes |
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Two types of neuron processes |
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The receiving or input portion of a neuron *These electrical signals are NOT nerve impulses (action potentials) they are short distance signals called GRADED POTENTIALS |
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propagates nerve impulses toward another neuron, a muscle fiber, or gland * They GENERATE and TRANSMIT nerve impulses (ACTION POTENTIAL) away from the cell body |
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An elevation where the axon joins the cell body (in the case of multipolar neurons) |
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the junction of the axon hillock and the initial segment *the site where most neuronal impulses arise |
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The plasma membrane surrounding the axoplasm *in the central NS, the axolemma may be exposed tot he interstitial fluid or it may be covered by the processes of neuroglia |
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Side branches of the axon *collaterals allow a single neuron to communicate with many other cells. |
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the axon and its collaterals end by dividing into many fine processes called axon terminals |
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the site of communication between two neurons or between a neuron and an effector cell |
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sends the message *usually a neuron |
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receives the message *a neuron or another cell type *neuromuscular junction, neuroglandular junction and adipocytes |
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aggregations of myelinated processes in regions of the brain and spinal cord |
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consists of neuronal cells bodies, dendrites, UNMYELINATED AXONS, axon terminals and neuroglia |
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Multiple sclerosis, diphtheria and heavy metal posioning |
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Sheath of Schwann *the outer nucleated cytoplasmic layer of the Schwann cell, which encloses the myelin sheath *A neurilemma is found only around axon in the PNS *the neurilemma aids in the repair of injured axons *a schwann cell can enclose portions of several unmyelinated axon too!! |
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Regeneration and Repair of Nervous tissue |
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Definition
*the cell body is intact *the schwann cells are functional *scar tissue formation does not occur too rapidly (astrocytes produce scar tissue) |
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Allows communication over short and LONG distances within the body |
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Used for short distance communication only |
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Used for short distance communication only |
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Leakage channels (Passive) |
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ALWAYS OPEN *The plasma membranes have many more K+ leakage channels that Na+ leakage channels |
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Open and close in response to a stimulus *The presence of gated ion channels in the plasma membranes of neurons and muscle fibers gives these cells their property of electrical excitability. |
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Voltage gated ion channels |
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Definition
*Opens in response to a change in membrane potential (voltage) *Used in the generation and conduction of action potentials *FOUND ON THE MEMBRANES OF EXCITABLE CELLS *Axons of unipolar and multipolar, sarcolemma and T tubules of skeletal muscle fibers and cardiac cells |
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Ligand gated ion channels (Chemically gated) |
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Definition
*Opens and closes in response to a specific chemical stimulus *found greatly on dendrites and cell body of neurons |
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Mechanically gated ion channels |
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Definition
*Opens and closes in response to mechanical stimulation (vibration, pressure, tissue stretching) *found in auditory receptors in the ears, in receptors that monitor stomach stretching, in touch receptors in the skin. |
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Change in resting membrane |
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Definition
ALL NEURAL ACTIVITIES START WITH A CHANGE IN THE RESTING MEMBRANE POTENTIAL OF A NEURON. *Change is produced by anything that changes membrane permeability to any type of ion, and anything that alters ion concentration on the two sides of the membrane. |
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Definition
reduction in the membrane potential *the inside of the membrane becomes less negative or more positive than the resting membrane potential |
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The membrane potential becomes more negative or less positive than the resting membrane potential |
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step by step depolarization of each adjacent portion of the plasma membrane. *this type of conduction occurs in muscle fibers and unmyelinated axons |
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occurs in myelinated axons (much faster and more efficient) *at the nodes of ranvier, the myelin sheath is interrupted and the axolemma has a high density of voltage-gated ion channels |
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Large diameter fibers and brief refactory periods *these fibers carry motor commands to skeletal muscles (268 mph) |
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smaller diameter axons and a somewhat longer refractory period (40 mph) |
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have the smallest diameter and the longest absolute refractory period (2 mph) *unmyelinated axon |
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carry information to the CNS about temperature, pain and general touch and pressure and they carry instruction from the CNS to smooth muscle, cardiac and glands |
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the delay that occurs between the arrival of the action potential at the synaptic knob and the effect it has on the postsynaptic membrane *the fewer synapes involved the shorter the total synaptic delay and therefore, the faster teh responses |
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when the neurotransmitter store cannot keep up with demand for the NT, teh synapse will be inactive until more neurotransmitter is available |
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