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Study of microorgaisms-
organisms you need a microscope to see.
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used the first microscope to observe the fruiting bodies (reproductive structures) of the common blue mold, Penicillium in 1664 |
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Basic Many of the basic processes in life are the same in all living things. Easier to study organisms that divide every 20 minutes than slower growing organisms (humans) Most of the living things on the earth are microbes |
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Antoni van Leeuwenhoek (1632-1723) |
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real master of the microscope, in 1684 began making microscopes (hard to focus) that were so good that they could see bacteria! Coined the term: “wee animalcules” discovered bacteria, free-living and parasitic microscopic protists, sperm cells, blood cells, microscopic nematodes and rotifers, |
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botanist who was instrumental in founding the science of Bacteriology. Classified bacteria using the genus bacillus for the first time. Found endospore forming bacillus. |
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French chemist. Showed that microbes were everywhere Showed that they did not develop from nothing (spontaneous generation) (using the swan-necked flask experiment) Sterilization Vaccines-anthrax, cholera, rabies. He mostly worked with animals and with wine (pasteurization). Swan neck flask experiment. |
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First to notice that some compounds come in two racemic forms-chirality. He separated enantiomerically pure crystals from wine and showed that they have different optical properties. |
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What "infectious disease" caused an increase in the death rate in 1980? |
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Ignaz Philipp Semmelweis (1818-65) |
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In 1847 he started having doctors wash their hands in a chlorine solution when they left the cadavers (to deliver babies) |
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started cleaning operating tools and theaters (operating rooms) with carbolic acid (phenol). Carbolic acid was also used to treat wounds which allowed them to heal without becoming infected. |
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Who invented the Carbolic Acid Atomizer |
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First to see Bacillus Anthracis and M. tuberculosis. Invented Acid Fast Staining. Won Nobel prize for his work on TB. |
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first to prove that microbes cause disease and to develop a medium for isolating pure cultures. |
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a series of tests to determine if a given microbe was the cause of the disease |
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Describe Koch's Postulates |
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1. suspected pathogenic org. should be present in all cases of the disease and absent from healthy animals. 2. suspected org. should be grown in pure culture. 3. Cells from a pure culture should cause disease in a healthy animal. 4. The organism should be re-isolated and shown to be the same as the original. |
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founded the science of Environmental Microbiology |
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Martinus Beijerinck and Sergei Winogradsky |
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Environmental Microbiology |
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how microbes interact metabolically with their environments. |
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Father of Virology; developed the enrichment culture techinique. |
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