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Bio 211 respiratory system OCTC
respiratory OCTC
144
Biology
Undergraduate 2
10/07/2012

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Term
hypercapnia
Definition
high blood CO2
Term
hypocapnia
Definition
low blood CO2
Term
most common cause of respiratory acidosis
Definition
hypercapnia
Term
most common cause of respiratory alkalosis
Definition
hypocapnia
Term
what respiratory diseases can lead to respiratory acidosis
Definition
pneumonia, cystic fibrosis, emphysema
Term
what can cause respiratory alkalosis
Definition
hyperventilation due to stress or pain
Term
corrective response to acidosis
Definition
hyperventilation
Term
corrective response to alkalosis
Definition
hypoventilation
Term
bohr effect
Definition
active tissues generate more CO2 and decreases pH thus promoting O2 unloading
Term
what does an elevation in tissue temperature do to O2 unloading
Definition
increases it
Term
is the amount of O2 present in active tissues more or less
Definition
less because active tissue consumes more O2
Term
what has a strong effect on respiration
Definition
pH
Term
what is the amount of O2 given up by hemoglobin at the capillary bed known as
Definition
utilization coefficient 22%
Term
venous reserve
Definition
O2 remaining in the blood that can sustain life 4-5 minutes in respiratory arrest
Term
decrease in pH does what to O2 unloading
Definition
increases it
Term
chloride shift
Definition
chloride from plasma enters RBC and bicarbonate ion exits RBC to plasma; CO2 carried as bicarbonate, dissolves in the plasma to lungs
Term
what is CO bound to hgb
Definition
carboxyhemoglobin
Term
where does CO bind on hgb
Definition
the heme group and binds tighter than O2
Term
3 ways CO2 is transported
Definition
bicarbonate ion dissolved in plasma 70%
carbaminohemoglobin insid RBC 23%
dissolved gas in plasma 7%
Term
does a thicker membrane cause decreased airflow
Definition
yes
Term
capillary bed gas exchange O2
Definition
O2 in capillary is higher than in cell so it diffuses out of capillary to tissue fluid to cells
Term
capillary bed gas exchange CO2
Definition
CO2 in cell is higher than in capillary so it diffuses out of cell to tissue fluid to capillary
Term
how is most O2 transported
Definition
bound to hemoglobin forming oxyhemoglobin (98.5%)
Term
3 variables that effect alveolar gas exchange
Definition
pressure gradients of gases
membrane thickness
membrane area
Term
does the diffusion of one gas influence the diffusion of any other gas
Definition
no
Term
valsalva maneuver
Definition
childbirth, urination, defecation, vomitting
Term
composition of air
Definition
79% N
21% O
.04% CO2
Term
henry's law
Definition
states that at the air-water interface, the amount of gas that dissolves in the water is determined by its solubility in wayer and its partial pressure in the air
Term
what removes particles from upper respiratory tract
Definition
sneezing
Term
what removes particles from lower respiratory tract
Definition
coughing
Term
eupnea
Definition
relaxed, quiet breathing
Term
apnea
Definition
temporary cessation of breathing
Term
dyspnea
Definition
labored, gasping breathing; shortness of breath
Term
hyperventilation
Definition
increase in pulmonary ventilation with anxiety, fever, high altitude
Term
hypoventilation
Definition
decrease in pulmonary ventilation with pneumonia, emphysema, cracked rib, dying process
Term
total lung capacity
Definition
vital capacity + residual volume; sum of all lung volumes
Term
vital capacity
Definition
max amount of air that can be exhaled after taking the deepest breath possible; total amount of air exchanged and is used to assess strength of thoracic muscles and pulmonary function
Term
residual volume
Definition
air remaining in lungs after max expiration
Term
expiratory reserve volume
Definition
air in excess of tidal expiration that can be exhaled with max effort or forced exhalation...sigh
Term
inspiratory reserve volume
Definition
air in excess of tidal inspiration that can be inhaled with max effort or deep breath...gasp
Term
tidal volume
Definition
air inhaled or exhaled in one quiet breath (one respiratory cycle)
Term
4 respiratory volumes
Definition
tidal volume
inspiratory reserve volume
expiratory reserve volume
residual volume
Term
bronchodilation
Definition
incease in diameter of bronchioles
Term
bronchoconstriction
Definition
reduction in diameter of bronchioles
Term
what stimulates brochodilation to increase airflow
Definition
epinephrine and sympathetic nerves
Term
what stimulates bronchoconstriction to decrease airflow
Definition
histamine, parasympathetic nerves (ACh), cold air, chemical irritants
Term
pulmonary compliance
Definition
ease with which lungs expand
higher = easier lung expansion
lower = more E needed to breathe
Term
3 factors to resistance to airflow
Definition
diameter of bronchioles
pulmonary compliance
surface tension of alveoli
Term
atelectasis
Definition
collapsed lung
Term
pneumothorax
Definition
presence of air in the pleural cavity
Term
the pressure that drives respiration is
Definition
atmospheric pressure
Term
boyles law
Definition
pressure of a given quantity of gas is inversely proportional to its volume
increase volume, decrease pressure
decrease volume, increase pressure
Term
charles law
Definition
the volume of a given quantity of gas is directly proportional to the absolute temperature
temp increase, volume increase
Term
what are the functions of parietal and visceral pleura during inspiration
Definition
cling together because of serous fluid due to cohesion of water (surface tension)
Term
atmospheric pressure is __________ at higher elevations
Definition
lower
Term
ventral respiratory group VRG
Definition
in medulla oblongata; primary generator of respiratory rhythm
Term
I neurons stimulate what nerve
Definition
phrenic
Term
what does the phrenic nerve due
Definition
causes contraction of diaphragm
Term
when diaphragm and external intercostal muscles contract, what happens to thoracic cage
Definition
enlarges and causes inspiration
Term
influences VRG
Definition
dorsal respiratory group DRG
Term
location of DRG
Definition
medulla oblongata
Term
what is the integrating center
Definition
DRG
Term
modifies the rhythm of VRG
Definition
pontine respiratory group PRG
Term
location of PRG
Definition
pons
Term
where does PRG receive input from
Definition
hypothalamus, limbic system, sensory cerebral cortex
Term
central chemoreceptors
Definition
located in medulla oblongata
respond to changes in pH of CSF
Term
pH of CSF reflects ______ in blood
Definition
CO2 levels
Term
peripheral chemoreceptors
Definition
located in carotid and aortic bodies
respond to pH of blood and O2/CO2 levels in blood
Term
where do peripheral chemoreceptors send signal
Definition
DRG
Term
drop in pH from increase in CO2 levels causes peripheral chemoreceptors to signal DRG then _______
Definition
DRG signals VRG to adjust breathing and we hyperventilate to blow off CO2
Term
where does control of breathing originate
Definition
frontal lobe of cerebrum (cerebral cortex)
Term
skeletal muscles can/cannot contract without nervous stimulation
Definition
cannot
Term
breathing involves coordination of multiple muscles and ____ to coordinate
Definition
CNS
Term
lungs do/do not ventilate themselves
Definition
do not
Term
what ventilates that lungs
Definition
skeletal muscles of trunk by volume changes of thoracic cavity
Term
high surface tension within the alveoli would ______ alveoli when you exhale
Definition
collapse
Term
great alveolar cells secrete
Definition
surfactant
Term
2 places of gas exchange
Definition
lungs and systems
Term
great alveolar cell function
Definition
repair alveolar epithelium and secrete surfactant
Term
lines bronchioles
Definition
ciliated cuboidal epithelium with well-developed layer of smooth muscle
Term
alveolar macrophages
Definition
most numerous cell in lungs
phagocytize pathogens
Term
why do we breathe?
Definition
ATP synthesis requires O2
Term
2 meanings of respiration
Definition
ventilation of lungs
use of O2 in cellular respiration
Term
pulmonary ventilation
Definition
breathing
inspiration = inhalation
expiration = exhalation
Term
what uses O2 in cellular metabolism
Definition
cellular respiration
Term
functions of respiratory system
Definition
provide O2/CO2 between air and blood
for speech and vocalization
sense of smell
eliminate CO2 to control pH
carry out step in synthesis of vasoconstrictor angiotensin II ACE converts angiotensin I into angiotensin II
creates pressure gradients between thorax and abdomen
helps to expel abdominal contents
conditions air: warms, moistens, cleans; routefor water loss and heat elimination
Term
pathway of air
Definition
nose-nasal cavity-pharynx-larynx-trachea-bronchi-bronchioles-alveoli
Term
2 divisions of respiratory
Definition
conducting and respiratory
Term
conducting
Definition
only for airflow; nostrils to bronchioles
Term
respiratory
Definition
alveoli/capillary exchange of gases
Term
upper respiratory tract
Definition
head/neck: nose, nasal cavity, pharynx, larynx
Term
lower respiratory tract
Definition
thorax: trachea, bronchi, bronchioles, alveoli
Term
function of nose
Definition
warm, cleanse, humidify inhaled air
detect odor
resonating chamber that amplifies voice
Term
nostrils
Definition
nares - anterior opening of nose
Term
divides nasal cavity
Definition
nasal septum
Term
bone/cartilage of nasal septum
Definition
vomer bone, perpindicular plate of ethmoid bone, septal cartilage
Term
bones of nasal cavity
Definition
ethmoid, sphenoid
Term
where do paranasal sinuses and nasolacrimal ducts drain
Definition
nasal cavity
Term
vestibule
Definition
lined with stratified squamous epithelium
Term
vibrissae
Definition
stiff guard hairsb that block insects and debris
Term
3 folds of tissue in nasal cavity
Definition
superior, middle, inferior nasal conchae
aka turbinate bones
Term
forms a narrow passageway beneath each conchae
Definition
meatus - superior, middle, inferior
Term
olfactory epithelium
Definition
where odors are picked up by olfactory cells
Term
lines nasal cavity
Definition
ciliated pseudostratified columnar epithelium
Term
role of mucus
Definition
traps inhaled particles
Term
lysozymes
Definition
destroy bacteria
Term
plasma cells and lymphocytes
Definition
defend body against inhaled pathogens
Term
paranasal sinuses
Definition
air filled spaces of maxillary, frontal, ethmoid and sphenoid bones
**reduces weight of skull**
Term
pharynx
Definition
oro-
naso-
laryngo-
Term
lines oropharynx
Definition
stratified squamous epithelium
Term
lines nasopharynx
Definition
pseudostratified columnar epithelium
Term
lines laryngopharynx
Definition
stratified squamous epithelium
Term
located within nasopharynx
Definition
auditory tubes and pharyngeal tonsil
Term
located within oropharynx
Definition
palaltine and lingual
Term
larnyx
Definition
voice box
Term
3 cartilages of larynx
Definition
epiglottic, thyroid, cricoid
Term
primary function of larynx
Definition
keep food and drink out airway to lungs
passageway for air to trachea
Term
glottis
Definition
vocal cords and opening between them
Term
epiglottis
Definition
flap of elastic cartilage that guards the opening of larynx/glottis
Term
epiglottic cartilage
Definition
elastic cartilage
guards the opening of larynx and glottis
Term
thyroid cartilage
Definition
largest - hyaline cartilage
Term
laryngeal prominence
Definition
anterior peak (fusion) of thyroid cartilage
Term
cricoid cartilage
Definition
consists of hyaline cartilage
connects larynx to trachea
Term
vestibular folds
Definition
closes glottis during swallowing
Term
vocal cords
Definition
produces sound when air passes thru them
Term
trachea
Definition
windpipe
connects larynx to r/l main bronchi
Term
hyaline cartilage rings
Definition
reinforce trachea and keeps from collapsing
Term
trachealis
Definition
contracts/relaxes to adjust airflow during sympathetic/parasympathetic nervous control
Term
lines trachea
Definition
ciliated pseudostratified columnar epithelium
Term
mucociliary escalator
Definition
mechanism for debris removal
Term
carina
Definition
directs airflow into r/l main bronchi
Term
base of lungs
Definition
rest on diaphragm
Term
apex of lungs
Definition
projects just above clavicle
Term
cardiac impression
Definition
indentation on l lung
Term
cardiac notch
Definition
part of cardiac impression is visible anteriorly
Term
bronchial tree
Definition
2 main bronchi
lobar bronchi
segmental
Term
lines bronchi
Definition
ciliated pseudostratified columnar epithelium
Term
muscularis mucosae
Definition
within mucus membrane
smooth muscle that contracts and relaxes to regulate airflow
Term
bronchioles
Definition
lacks supportive cartilage
Term
lines bronchioles
Definition
ciliated cuboidal epithelium
Term
most numerous cells in lung
Definition
alveolar macrophages
Term
alveolar macrophages
Definition
phagocytize pathogens
Term
IRDS
Definition
infant respiratory distress syndrome
Term
functions of pleurae/pleural fluid
Definition
reduce friction by secreting pleural fluid
maintains surface tension to aid in breathing
compartmentalization prevents spread of infection in organ,lungs,lobes
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