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BIO 2010
Biology flashcards
74
Biology
Undergraduate 1
07/16/2013

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Term
Essential Elements
Definition

 25

CHON 96%

most mass O

most atoms H

Term

Electronegativity 

CHON

Definition

 O & N more electronegative 

C & H less electronegative 

 

Term
Covalent
Definition

nonpolar = C-H & O-O --> Same electronegativity

 

polar = O-H & N-H --> partial pos. & neg. 

Term
Hydrophilic
Definition

pos. & neg. charges

unequal sharing electrons - polar

water loving

Term
Hydrophobic
Definition

neutral charge 

equal sharing of electrons - nonpolar covalent

Term
Organic Molecules
Definition
Molecules which contain carbon and hydrogen
Term
Enantiomers
Definition

Isomers 

mirror images = hands

Term
Asymetric Carbon
Definition

Carbon bonded to 4 different groups

Enantiomers

Examples:

Ibuprofen to Albuterol

D-glucos & L-glucose

Term

Glucose Polysaccharides

 

Definition

polymers glucose

Cellulose - beta glucose -plants

Starch - alpha glucose - plants

Glycogen - alpha glucose - animals

Term
Nonpolar R groups
Definition
[image]
Term
Polar R groups
Definition
[image]
Term
Charged R groups
Definition

[image]

Negative = acidic --> carboxyl

Positive = basic --> amino

Term
Dehydration Synthesis
Definition

Carboxyl loses OH = Carbonyl

COOH to C=O

Amino acid adds to new Carbonyl end

H20 leaves

 [image]

Term
Nucleotide Structure
Definition

Phosphate 

Sugar (#1-5)

Nitrogenous base (A,T,U,C,G)

 

Sugar - Phosphate backbone

add onto 3' end

Term
Nitrogenous Bases
Definition

H bond

A, T , U=2 H

C-G = 3 H

 

 

Term
Purines
Definition

2 Carbon Rings

 

A & G

Term
Pyrimidines
Definition

1 Carbon Ring

 

C, T, U

Term
Lipids
Definition

Fats = fatty acids + glycerol

Phospholipids = fatty acids + glycerol + choline +phosphate

Steroids = 4 fused carbon rings

Term
Kinases
Definition

protein enzymes

catalyze transfer of phosphate to another molec.

Example 

ATP to Protein molec.

=ATP to ADP

Term
Phosphatases
Definition

protein enzyme

catalyze removal of phosphate to free phosphate

Example:

active protein + phosphate

phosphatase removes

= inactive protein & free phosphate

Term
Prokaryotes
Definition

1 circular chromosome

mostly unicellular

no membrane bound organelles

no distinct nucleus

small in size

bacteria; archaea

phospholipid membrane

ribosomes & DNA

Term
Eukaryotes
Definition

several linear chromosomes

membrane bound organelles (prokaryotes)

bigger in size

multicellular

DNA in nucleus

Term
Amphipathic
Definition

hydrophilic & hydrophobic

membranes of molecules

biles, soap

Term
Fluidity of Cell Membrane
Definition

amphipathic phospholipid bilayer

moves - not covalently bonded

Term

Cell Membrane:

Nonpolar (hydrophobic) substances

Definition
can freely cross
Term

Cell Membrane:

Polar (hydrophilic) substances

Definition
Active transport through special protein channels
Term
Second Law of Thermodynamics
Definition
Energy always spreading out (diffusing) then Entropy (S) is always increasing.
Term
High Energy Electron Donor
Definition

Oxidized

Acts as Reducing agent

Term
Low Energy Electron Acceptor
Definition

Reduced

Acts as Oxidizing agent

Term

Electron Acceptors/Donors:

Photosynthesis

Definition

high energy donor: H20 + chlorophyll + sun --> O2

low energy acceptor: CO2 --> macromolecules

Term

Electron Acceptors/Donors:

Respiration

Definition

high energy donor: macromolecules --> CO2

low energy acceptor: O2 --> H2O

Term
Mitochondria
Definition

2 phospholipid bilayers

breakdown sugars to make ATP

 

Term
Cristae
Definition
folds in mitochondria
Term
Matrix
Definition
inner part mitochondria (cytoplasm)
Term
Aerobic Respiration
Definition

make ATP

exhale CO2 from sugars & fats

 

Glycolysis

pyruvate oxidation

citric acid cycle

electron transport chain

Term
Glycolysis
Definition

Gluse phosphorylate 2x = fructose

Fructose splits = 2 G3P

6 Carbon --> 2 G3P

electrons removed from G3P = NADH

PGK & pyruvate kinase remove phosphates = ATP

2 G3P --> 2 Pyruvate + ATP + NADH

Term
Pyruvate Oxidation
Definition

Pyruvate into mitochondrion

Carboxyl removed = CO2

electrons removed = NADH

Acetyl attaches to Sulfer on CoA

3 Carbon to 2 Carbon

&

CO2 + NADH

 

Term
Citric Acid Cycle
Definition

acetyl leaves CoA

add to 4C oxaloacetate

= 6C citrate

2 carbons removed = CO2

electrons removed = NADH 

CoA aids in ATP formation

2 C to 2 CO2 + ATP + NADH

Term
Electron transport chain
Definition

electrons from glycolysis, pyruvate oxidation, and citric acid drive ATP synth. with ATP synthase

inner mitochondrion = cristae 

O2 final electron acceptor = form H2O

Term
Inner memberane Mitochondrion
Definition
High proton concentration
Term
Chemiosmosis
Definition

facilitated diffusion of protons into mitochondrial matrix

= drive ATP production

Term
ATP synthase
Definition

facilitates proton diffusion

attach phosphate to ADP --> ATP

Term
Respiration in Prokaryotes
Definition

ATP synthase on cell membrane

ion gradient

 

anaerobic respiration

Term
Anaerobic Respiration
Definition
without O2
Term
Fermentation
Definition

usually only glycolysis

glucose --> pyruvate

coupled to ATP production

no ATP synthase with proton gradient

Term
Chloroplasts
Definition

2 phospholipid membrane

Thykaloids

Stroma (cytoplasm)

Term
Thykaloid
Definition

phospholipid bilayer

harvest light 

ATP made on its membrane

chlorophyll here

Term
Photosystem II
Definition

get electrons from H2O

feed into eletron transport chain

Term
Photosystem I
Definition

gets electrons from transport chain

re-excited by sunlight energy

Term
Calvin cycle & glycolysis
Definition
both use G3P
Term
Phases of Mitosis
Definition

G2 interphase

prophase

prometaphase

metaphase

anaphase

telophase & cytokinesis

 

exact copy

Term
Meiosis
Definition

Prophase

metaphase

anaphase 

telophase & cytokinesis 

2rounds 

1st round homologous crossover in prophase

Term
Apoptosis
Definition

programmed cell death 

 

Term
Alleles
Definition
different versions of the same gene
Term
DNA nucleotide
Definition
nitrogenous base + ribose + phosphate
Term
Base Pairs
Definition
2 nucleotides, hydrogen bonds
Term
DNA sequence
Definition
any continuous region of DNA bases
Term
Gene
Definition
region of DNA that can be made into RNA
Term
Chromatin
Definition
DNA + proteins
Term
Chromosome
Definition

Single strand DNA and proteins to condense it

lots of genes

Term
Genome
Definition

all DNA in cell 

(1 or several chromosomes)

Term
Aneuploidy
Definition
abnormal number of chromosomes
Term
Primase
Definition
enzyme that adds RNA primer to single DNA during its replication
Term
Where is DNA added
Definition
to the 3' nucleotide only
Term
Leading strand
Definition
continuously made as helicase undwinds
Term
Lagging strand
Definition
has to be primed several times
Term
Ligase
Definition
pieces together lagging strand
Term
Gene expression
Definition

DNA to protein

Transcription

RNA processing - mrna

Translation-ribosome, polypeptide

Term
Translation
Definition

mRNA to protein

 

Term
tRNA
Definition

tRNA brings amino & pairs with mRNA

 

Term
Ribosome
Definition
binds amino together
Term
Start Codon
Definition
AUG - methionine
Term
Stop Codon
Definition
UAA, UAG, UGA
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