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Bio 150: Chapter 13
Chromosomes, Mapping, and the Meiosis--Inheritance Connection
13
Biology
Undergraduate 1
04/06/2014

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Term
Define the chromosomal theory of inheritance:
Definition
The theory that hereditary traits are carried on chromosomes
Term
What model system did Thomas Hunt Morgan use to correlate inheritance with sex chromosomes? What are the wildstype and mutant ewye colors in this organism.
Definition
Mendelin system, red and white. Wild types: normal phenotypes common in flies. and the Mutant eye are phenotypes alternate to phenotypes
Term
What testcross was performed to explain the F1 cross that Morgan conducted.
Definition
Morgan test crossed the female Fprogeny with the original white eyed male.
Term
What are the sex chromosomes? Where does the eye color gene lie in Morgan's model organism?
Definition
X and Y chromosomes are the sex chromosomes. Resides only on the x-chromosome.
Term
What does it mean for a gene to be sex-linked?
Definition
A trait determined by a gene on the x chromosome is said to be sex-linked
Term
Describe the relationship between sex chromosomes and sex determination:
Definition
XY XX, Male and Female but some disorders can go against that.
Term
What are autosomes?
Definition
Perfectly matched pairs of chromosomes
Term
Why is the Y chromosome said to determine maleness in humans?
Definition
Some active genes on Y chromosome are responsible for mascutazation
Term
What is a sex linked disorder?
Definition
Disorders associated with specific sex
Term
What is the dosage compensation? How does this prevent doubling of sex-linked gene products?
Definition
It ensures an equal level of expression from the sex chromosomes despite a differeing number of sex chromosomes in males and females
Term
What is X-chromosome inactivation? How does it lead to mosaics?
Definition
Females that are heterozygous for x chromosome allels are genetic mosaics; their individual cells may express different allels, depending on which chromosome is inactive. X-chromosome inactivation to produce dosage compensation.
Term
Traits that are controlled by genes located on the x-chromosome are said to be ___________.
Definition
Sex-linked
Term
In and organisms genome, autosomes are...
Definition
All of the chromosomes other than sex chromosomes
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