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Bio 15
Chromosomes as the Basis of Inheritance
36
Biology
Undergraduate 1
10/22/2012

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Term
What is the system of sex determination in humans?
Definition
The X-Y system where XX is female and XY is male
Term
How is gender determined in the system of sex determination in humans?
Definition
The sperm contains half Y's and half X's
Term
What is the system of sex determination in some insects?
Definition
X-O system, where XX is female and XO (one chromosome) is male.
Term
What determines the system of sex determination in insects?
Definition
The sperm.
Term
What is the system of sex determination in birds, some fishes and some insects?
Definition
Z-W system, where ZW is female and ZZ is male.
Term
What determines the sex determination in some fish, butterflies, birds?
Definition
The egg.
Term
Which species have the most chromosomes?
Definition
Bees and ants.
Term
Are there sex chromosomes in most species of ants and bees?
Definition
No.
Term
How do females form in ants and bees?
Definition
From fertilized eggs as diploids.
Term
How do males form in ants and bees?
Definition
From unfertilized eggs as haploid from sperm going through mitosis.
Term
X chromosome inactivation
Definition
One female chromosome remains inactive in each cell.
Term
Since females have two X chromosomes, do they code for twice the number of proteins from those X-linked genes?
Definition
No. X chromosome inactivation prevents that.
Term
Barr body
Definition
The condensed inactive X chromosome in females.
Term
How is the Barr body determined in each cell?
Definition
Inactivation occurs independently of one another. when the embryo is at ~200 cells.
Term
Does the Barr Body change during mitotic division?
Definition
No. It stays inactive.
Term
What is an example of a phenotype affected by X inactivation?
Definition
A tortoiseshell cat.
Term
Linked Genes
Definition
Genes inherited together in genetic crosses because of their close proximity to one another.
Term
Crossing Over
Definition
Gene exchange between homologous chromosomes during Prophase 1 of meiosis.
Term
What influences Crossing Over?
Definition
The distance between genes and the distance from the centromere. In both cases, the farther away, the more often crossing over occurs.
Term
Genetic disorders may be...
Definition
Dominant, recessive, autosomal and sex linked.
Term
Sex linked Genes
Definition
Genes located on X-chromosomes in humans.
Term
Hemizygous
Definition
Having only one allele for a gene, which males have.
Term
Are males homozygous or heterozygous for genes on the X chromosome?
Definition
Neither -- they are hemizygous.
Term
Which gender can be heterozygous for sex-linked genes?
Definition
Only females.
Term
What is an autosomal recessive trait?
Definition
Sickle-cell anemia.
Term
What results from Sickle-cell anemia?
Definition
Mis-formed hemoglobin.
Term
Pedigree
Definition
A family tree presentation of a genotype and phenotype.
Term
Carrier
Definition
An individual that is heterozygous for a recessive condition.
Term
Does a carrier express the condition?
Definition
No, but they can pass it om.
Term
Normal Human Karyotype
Definition
Individual homologous chromosomes displayed in order from longest length to shortest length.
Term
Polyploidy
Definition
Having 1+ additional sets of chromosomes.
Term
What happens as a result of Polyploidy?
Definition
Fatal in humans, but plants seem fine.
Term
Aneuploidy
Definition
More of fewer chromosomes than the normal amount present.
Term
What may happen due to Aneuploidy?
Definition
Embryo miscarriage
Term
Non-disjunction
Definition
When homologous chromosomes in Anaphase 1 or sister chromatids in Anaphase 2 fail to separate.
Term
How does non-disjunction occur?
Definition
Through aneuploidy
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