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groups of muscle cells/fibers |
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long bundles of myofibrils |
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organized into sarcomeres ("contractile unit" of muscles) |
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cytoplasm of muscle cell; myofibril, myoglobin, glycogen |
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has T-tubules filled with extracellular fluid |
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myosin protein binds/hyrolyzes ATP; consists of hundreds of myosin heads (golf club) |
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two chains of actin protein; each actin unit has an active site that can bind myosin head; tropomyosin blocks active site in relaxed muscles; troponin binds tropomyosin and calcium |
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movement; communication; stability; control of body openings; heat production |
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excitability; conductivity; contractility; extensibility; elasticity |
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voluntary, multinucleate, striated, attached to bone/skin/fascia |
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involuntary; striated; mononucleate; autorhythmic |
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involuntary; non-striated; mononucleate; hair follicles/walls of hollow organs |
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thick filament; partially overlaps with thin filament |
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contraction of all sarcomeres, in all myofibrils, in all cells... |
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causes the muscle to contract as a whole |
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4 major stages of muscle contraction |
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1. excitation 2. excitation-contraction coupling 3. contraction 4. relaxation |
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communication between neuron and mmuscle cell |
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excitation-contraction (general) |
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conversion of action potential in muscle cell to activation of protein in sarcomere |
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muscles develop tension and may shorten |
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potassium leaves the cell; but more sodium enters than potassium leaves |
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end-plate potential (EPP) |
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action potential; Na+ channels open on motor plate |
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function of sarcoplasmic reticulum |
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Definition
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voltage-gated Na+ channels in T tubules are physically to... |
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Definition
Ca+ ion channels in sarcoplasmic reticulum |
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calcium released by SR... |
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Definition
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troponin-tropomyosin complex changes shape and exposes... |
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Definition
active sites on thin filaments |
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active transport needed to... |
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Definition
pump calcium back into sarcoplasmic reticulum |
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total muscle contraction= |
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Definition
sum of individual muscle cell contraction |
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