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Bio 124 Lecture 4
Endocrine system
20
Biology
Undergraduate 1
02/25/2013

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Term
where is the hypothalamus found?
Definition

at the base of the brain

 

the pituitary gland dangles off the hypothalamus

Term
name the 3 functions of the hypothalumus
Definition
  • secretion of regulatory hormones to control activity of anterior pituitary
  • control of sympathetic output to adrenal medullae
  • production of ADH and oxytocin
Term
which part of the pituitary gland is an overgrowth of the hypothalamus?
Definition

the posterior pituitary gland (PPG)

 

PPG is also known as neurohypophysis 

Term
what joins the PPG to the hypothalamus?
Definition
the infundibullum joins the PPG to hypothalamus
Term
the supraoptic nuclei of the hypothalamus produce which hormone?
Definition

ADH

 

the paraventricular nuclei produce oxytocin

Term
there is no direct route from the hypothalamus to the anterior pituitary gland (APG) how does hormones secreted by hypothalamus get to the APG?
Definition

 

 

hypothalamus produces regulatory hormones and releases into the Median Eminence. the hormones get to the APG via diffusion through the hypophyseal portal system.

Term
what is a portal vein?
Definition

where two capillary beds are linked via a vein.

 

 

C-v-C

Term
what are tropic hormones?
Definition

they are hormones that regulate the release of hormones from other endocrine glands

 

eg. thyroid stimulating hormone and follicle stimulating hormone are both tropic hormones

Term
name 7 hormones that are released from the APG
Definition

TSH - thyroid stimulating hormone

ACTH - adrenocorticotropic hormone

FSH - follicle stimulating hormone

LH - luteinising hormone

Prolactin (PRL)

GH - growth hormone

MSH - Melanocyte stimulating hormone

Term
MSH regulates pigment containing cells in reptiles and amphibians. In mammals it acts on neurons in the brain to inhibit hunger. Where is MSH produced?
Definition

in the pars intermedia of the APGland.

 

this is the bit that butts up againts the PPGland

Term
Which hormone controls the glycoprotein thyroid stimulating hormone?
Definition
thyrotrophin releasing hormone. this is released from the hypothalamus which gets the anterior pituitary gland to secrete thyroid stimulating hormone AKA Thyrotrophin.
Term
what does TSH target?
Definition
targets the thyroid to produce T3 and T4
Term

what type of hormone is Adrenocorticotropic hormone (corticotropin)?

what does it stimulate?

what is it controlled by?

where is it released from?

Definition

it is a peptide hormone

it stimulates the adrenal cortex

it is controlled by Corticotropin releasing hormone (CRH)

it is secreted from the anterior pituitary gland.

Term

FSH and LH are known as gonadotropins.

where are they released from?

what type of hormones are they?

what do they stimulate?

what are they controlled by?

Definition

released from APGland

thye are glycoprotein hormones

they stimulate the gonads

they promote egg and sperm production

they are controlled by Gonadotropin releasing hormone (GRH)

Term
what is the peptide that both ovaries and testes produce that has negative feedback effects?
Definition
Inhibin
Term

prolactic AKA mammotropin targets mammary glands for lactation and milk production.

what is it stimulated and inhibited by?

what type of hormone is it?

where is it released from?

Definition

stimulated by Prolactin releasing factor (PRF)

inhibited by Prolactin inhibiting hormone (PIF, dopamine)

it is a peptide hormone

released from anterior pituitary gland

Term
which hormone is also known as somatotrophin has both tropic and non tropic effects?
Definition

growth hormone.

 

  • this is a peptide that stimulates insulin like growth factor production.
  • stimulates fat and glycogen breakdown
  • it is inhibited by growth hormone inhibitory hormone (GHIH)(somastatin)
  • stimulated by growth hormone releasing hormone (GHRH)

 

 

Term
in relation to growth hormone abnormalities what can a lack of growth hormone result in?
Definition
pituitary growth failure
Term
what are the conditions associated with excess GH before puberty and excess GH after puberty?
Definition

before puberty - Gigantism

after puberty - Acromegaly

Term
name the 2 hormones secreted by the posterior pituitary gland
Definition

ADH

and

Oxytocin (a peptide hormone that excites uterine wall during child brith and stimulates release of milk).

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