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Bio 120 Test 1
T1 review
263
Biology
Undergraduate 1
02/13/2012

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Term
Thiols have this functional group
Definition
Sulfhydryl
Term
First to see cells; they were from oak bark
Definition
Robert Hook
Term
All amino acids have:
Definition
Carboxyl group, amino group, hydrogen, R-group
Term
This isomer differs in the way their atoms are attached
Definition
Structural isomers
Term
The purines
Definition
Adenine and guanine
Term
Why are steroids and phospholipids key components of plasma membranes?
Definition
Because they both have hydrophilic heads and hydrophobic tails (amphipathic)
Term
How was the double helix shape first detected?
Definition
X-ray crystallography
Term
Why is a particular membrane less permeable?
Definition
Straight tails on the phospholipids (saturated fatty acids) so they fit together better
Term
Condensation reactions bond the carboxyl group of one amino acid to the amino group of another amino acid to form a....
Definition
peptide bond
Term
The difference between ribose and deoxyribose
Definition
Deoxyribose has one less oxygen atom
Term
Which substances cross lipid bilayers (membranes) slowly or not at all?
Definition
Large molecules and ions
Term
The most abundant element in cells
Definition
Hydrogen
Term
The hypothesis that explains how carbon containing compounds could have formed more complex, living molecules
Definition
Chemical evolution
Term
Only certain substances can cross easily
Definition
Selectively permeable
Term
All organisms are made of cells and all cells come from preexisting cells
Definition
Cell theory
Term
The amount of rungs in one turn of the helix
Definition
10
Term
The kind of bond that holds the strands of the helix together
Definition
Hydrogen bonds
Term
A protein's ______ _______ is the
Definition
Primary structure
Term
A ______ protein is unable to function normally
Definition
Denatured / unfolded
Term
In a neutrally charged atom these are always equal
Definition
The number of protons and electrons
Term
Changes in populations that occur when humans select individuals to produce certain offspring
Definition
Artificial selection
Term
Pasteur disproved this hypothesis using a swan neck
Definition
Spontaneous generation
Term
Of the most abundant elements in organisms, this one can have the most chemical bonds
Definition
Carbon
Term
The two conditions that must be met in order for natural selection to occur
Definition
Variability in a heritable way and varieties of heritable traits result in survival (fitness)
Term
The bonds between monosaccharides to form a polysaccharide
Definition
Glycosidic linkages
Term
A family of lipids with a bulky, four-ring structure
Definition
Steroids
Term
The 7 levels of Linnaean taxonomy in order from largest to smallest
Definition
Kingdom, phylum, class, order, family, genus, species
Term
This occurs when a molecule similar in size and shape to the substrate competes with the substrate for active site bonding
Definition
Competitive inhibition
Term
The theory which states that RNA was the first lifeform
Definition
RNA world hypothesis
Term
A glycerol linked to a phosphate group and two fatty acids or two isoprene chains
Definition
Phospholipid
Term
When water reacts with a polymer to release a monomer
Definition
Hydrolysis
Term
Polysaccharides commonly used for storage or structure
Definition
Starch, chitin, glycogen, cellulose, peptidoglycan
Term
In secondary structure, hydrogen bonds form between...
Definition
Peptide chains
Term
Linneaean taxonomy is based off of these two levels of classification
Definition
Genus and species
Term
The sugar in RNA
Definition
Ribose
Term
Proteins with covalent bonds to carbohydrates
Definition
Peptidoglycans, glycoproteins
Term
The biologists whose research revealed the helical shape
Definition
James Watson and Francis Crick
Term
The kingdom that includes all prokaryotes
Definition
Monera
Term
This type of isomer differs in the arrangement of atoms around a double bond
Definition
Geometric
Term
The movement of molecules and ions that results from kinetic energy
Definition
Diffusion
Term
The kind of bond that forms between nucleotides in the backbone of nucleic acids
Definition
Phosphodiester bonds
Term
It keeps excess sodium ions outside the cell and excess potassium ions inside
Definition
Sodium-potassium clumps
Term
This bond allows carbohydrates to have more free energy
Definition
Carbon-hydrogen bonds
Term
5 fundamental characteristics of organisms
Definition
Energy, cells, information, replication, and evolution
Term
A change in the characteristics of a population over time
Definition
Evolution
Term
The term which is used to describe R groups which do not react well with water
Definition
Hydrophobic
Term
Fats, steroids, and phospholipids
Definition
The three main types of lipids
Term
Either a trios, pentose, or hexose
Definition
Monosaccharide
Term
Cell theory
Definition
All organisms are made of cells, and all cells come from preexisting cells
Term
Robert Hooke
Definition
The first person to recognize cells, viewed in oak bark
Term
Anton van Leeuwenoek
Definition
A lens manufacturer who, with better microscopes, was the first to see single-celled "animalcules" in pond water
Term
Spontaneous generation
Definition
The original theory that cells came from nowhere, but this was because their causes (like fly eggs, spores, etc.) were not observable.
Term
Pasteur experiment
Definition
The experiment that disproved the spontaneous generation hypothesis; he put nutrient-rich broth in a swan-necked flask and boiled it to kill all the cells already in it. Then, when preexisting cells tried to enter, they were caught in the swan neck and reproduced, while the broth in the flask itself remained sterile.
Term
Evolution
Definition
1. Species are interrelated and can change through time.
2. A change in allele frequencies within a population
Term
Natural selection
Definition
A change in the genetic makeup of a population. Two conditions must be met:

-Individuals must vary in a heritable way
-Varieties of heritable traits affect fitness
Term
Fitness
Definition
The ability for an animal to survive and reproduce
Term
Artificial selection
Definition
When humans breed things to have pleasing characteristics (Brassica oleracea to have thick stalks and so become broccoli, dog breeding, etc.)
Term
Carolus Linnaeus
Definition
In 1735 he developed Linnaean taxonomy (the binomial nomenclature system using genus and species)
Term
Linnaean taxonomy
Definition
Kingdom, phylum, class, order, family, genus, species
Term
Taxonomy
Definition
The science of classifying organisms
Term
Two main taxonomic groupings
Definition
Eukaryotes and prokaryotes
Term
Eukaryotes
Definition
Have a membrane-bound nucleus
Term
Prokaryotes
Definition
Developed before eukaryotes, do not have a membrane-bound nucleus. They are bacteria.
Term
Five kingdoms
Definition
Mammalia, Monera (the only prokaryotic kingdom), Protista (mostly single-celled organisms), Plantae, Fungi
Term
Molecules in classification
Definition
The sequence of nucleotides in rRNA determines an organism's genetic makeup. The closer these sequences are between two species, the closer they are on the tree of life in classification.
Term
Three domains
Definition
Archaea, Bacteria, Eukarya
Term
Chemical evolution hypothesis
Definition
Explains how complex carbon-containing compounds (and life) could have formed from simpler molecules
Term
Condensation theory
Definition
The theory that earth and the moon formed from the same nebula; unaccepted because of the dissimilarity of their makeups (the moon should have an iron core).
Term
Radiometric dating
Definition
Using carbon-14 to estimate the earth's age and when life first appeared
Term
Isotopes
Definition
Forms of an element with a different number of neutrons
Term
Radioactive isotopes
Definition
Isotopes which decay over time, releasing radiation particles to form new daughter isotopes
Term
Radioactive decay
Definition
The process by which radioactive isotopes are formed
Term
Half-life
Definition
The time it takes for half of a quantity of an isotope to decay
Term
Age of the earth
Definition
About 4.5 billion years; this is determined based on dating the moon and meteorites, because the earth was molten at its start, making radiometric dating impossible.
Term
When did life appear?
Definition
~3.8 bya; carbon grains were found with high carbon-12 concentration, which living organisms prefer because of its lighter weight.
Term
Building blocks of chemical evolution
Definition
Carbon, hydrogen, oxygen, and nitrogen. 96% of cells are made up of these. They usually have at least one unpaired valence electron, which allows pairing and chemical bonding.
Term
Covalent bonding
Definition
Sharing of electrons between two atoms
Term
Nonpolar covalent bonds
Definition
Electrons are shared equally (the atoms have equal electronegativity)
Term
Polar covalent bonds
Definition
Uneven sharing of electrons (unequal electronegativity)
Term
High electronegativity
Definition
Holds electrons more tightly and has a partial negative charge (delta-)
Term
Low electronegativity
Definition
Holds electrons more loosely and has a partial positive charge (delta+)
Term
Ionic bonding
Definition
Electrons are completely transferred from one atom to another
Term
Cation
Definition
Positive ion; missing electrons
Term
Anion
Definition
Negative ion; has extra electrons
Term
The octet rule
Definition
An atom can have 8 electrons in its outer valence shell
Term
Common single covalent bonds
Definition
Methane (CH4), water (H2O), ammonia (NH3)
Term
Double and triple bonds
Definition
Can occur if there are two or three unpaired electrons, respectively
Term
Common double bonds
Definition
Carbon dioxide (CO2)
Term
Common triple bonds
Definition
Nitrogen (N2)
Term
Bond angles
Definition
Angles between the bonds, which determine the shapes of molecules. Bond angles depend on the orbitals in the bond.
Term
Molecular formula
Definition
States the numbers and types of atoms in a molecule
Term
Structural formula
Definition
Shows which atoms are bonded together and indicates double and triple bonds, but not 3D geometry
Term
Space-filling model
Definition
Shows atom sizes in a molecule relative to one another
Term
Ball-and-stick model
Definition
Shows a molecule with sticks connecting the balls representing bonds between atoms
Term
Main colors of 3D models
Definition
Hydrogen - white, carbon - black, nitrogen - blue, oxygen - red
Term
Molecular weight
Definition
Sum of the mass numbers of all the atoms in a molecule (in amu)
Term
Mole
Definition
6.022e23 molecules, with a mass equal to the molecular weight but expressed in grams
Term
Molarity
Definition
Expresses concentration of a solute in solution in moles/liter (M)
Term
Main components of the early atmosphere
Definition
Volcanic gases, mostly CO2, N2, and H20
Term
Secondary components of the early atmosphere
Definition
H2, NH3, and CH4, important because they could form formaldehyde (H2CO) and hydrogen cyanide (HCN)
Term
Redox (reduction-oxidation) reaction
Definition
One molecule in the reaction is oxidized and one is reduced. An electron donor is always paired with an electron acceptor. This kind of reaction results in a loss of potential energy.
Term
Oxidation
Definition
Losing electrons; in biological systems, this usually translates to losing hydrogen
Term
Reduction
Definition
Gaining electrons; in biological systems, this usually translates to gaining hydrogen
Term
The versatility of carbon allows...
Definition
...it to form multiple bonds with many molecules in a variety of different shapes (like straight lines with octane (C8H18) or rings with glucose (C6H12O6)). This facilitated the formation of complex organic molecules.
Term
Organic molecules
Definition
Molecules found in organisms, which contain C-C bonds
Term
Reaction to produce formaldehyde
Definition
CO2 + H2 -> H2CO + H2O; reduction
Term
Chemical evolution step 1
Definition
Simple molecules (carbon monoxide, carbon dioxide, water, hydrogen, ammonia, and nitrogen) were present in the early atmosphere
Term
Chemical evolution step 2
Definition
Simple molecules formed into more complex molecules with reduced carbon, like formaldehyde and hydrogen cyanide, through redox reactions in the presence of light
Term
Chemical evolution step 3
Definition
After heating, molecules with reduced carbon combined to form even more complex molecules with C-C bonds, like ribose, acetaldehyde, and glycine
Term
Functional groups
Definition
Groups containing H, N, or O atoms that bonded to molecules structured around carbon to determine their function
Term
Six common functional groups
Definition
Amino, carbonyl, carboxyl, hydroxyl, phosphate, sulfhydryl
Term
Amino group
Definition
Acts as a base, oftentimes attracting proteins
Term
Carbonyl group
Definition
Aldehydes and ketones; aldehydes especially react with molecules to produce HR2, with form
Term
Carboxyl group
Definition
Acts as an acid; tends to lose a proton in formation
Term
Hydroxyl group
Definition
Highly polar, so makes compounds more soluble through hydrogen bonding with water
Term
Phosphate group
Definition
Breaking O-P bonds between several linked phosphate groups releases lots of energy
Term
Sulfhydryl group
Definition
If present in proteins, these can form S-S bonds, which contribute to protein structure
Term
Solvent
Definition
Something that dissolves substances
Term
Why is water an efficient solvent?
Definition
Because H-O bonds are polar (oxygen has high electronegativity). This means molecules are pulled toward the oxygen and hydrogen bonds might form. These help solutes stay in solution
Term
Structure of water
Definition
Small, bent shape, and highly polar bonds
Term
How does water's structure contribute to its physical properties?
Definition
It is less dense when frozen (since there are more hydrogen bonds connecting molecules in a crystal pattern) and can absorb a lot of heat (because of its high specific heat; ~4.18 liquid and 2.03 solid)
Term
Specific heat
Definition
Amount of energy required to raise one gram of a substance 1 degree Celsius
Term
Heat of vaporization
Definition
Amount of energy required to change one gram of a substance from liquid to gas
Term
Importance of water's properties
Definition
Its heat absorption capacity would have protected hydrogen cyanide and formaldehyde in solution from disruption in the early environment (asteroids, volcanoes)
Term
Acid
Definition
A proton donor
Term
Base
Definition
A proton acceptor
Term
Acid-base reactions
Definition
An acid transfers protons to a base
Term
pH scale
Definition
Logarithmic; pH = -log(H+)
Term
Stanley Miller
Definition
A graduate student who in 1953 performed a spark discharge experiment to study chemical evolution
Term
Spark discharge experiment
Definition
Two flasks; one containing boiling water (early ocean) and the other containing ammonia, methane, and hydrogen (early atmosphere). With the addition of electricity (lightning) to the atmosphere flask, the water changed colors and hydrogen cyanide and formaldehyde were found, even along with some amino acids (the second part of chemical evolution)
Term
Amino acids
Definition
The subunit (monomer) of proteins; there are 20 of them. They all have: NH2 (amino group), COOH (carboxyl group), H, and an R group around a central carbon.
Term
Amino acids in water
Definition
This makes the ionized form of the amino acid; the amino group has a positive charge and acts as a base, while the carboxyl group acts as an acid
Term
How do the amino acids differ?
Definition
In their R groups, which vary in size, shape, reactivity, and interaction with water
Term
Nonpolar R groups
Definition
There are no charged atoms to form hydrogen bonds, so they are not soluble in water
Term
Polar R groups
Definition
They have partial charges and so can form hydrogen bonds and are water soluble
Term
Electrically charged R groups
Definition
Split up into acids and bases; they are highly soluble in water because of the charges
Term
Hydrophobic
Definition
Not reactive with water
Term
Hydrophilic
Definition
Reactive with water
Term
Isomers
Definition
Molecules with the same molecular formula but varying structures
Term
Structural isomers
Definition

Differ in the order in which their atoms are attached:

H H

|  |

Ethanol: H-C-C-OH

 | |

H H

 

H    H

|     |

Dimethyl ether: H-C-O-C-H

|     |

H    H

Term
Geometric isomers
Definition
Differ in the arrangement of atoms about a double bond
Term
Optical isomers
Definition
They are mirror images of one another; there are right-handed and left-handed forms, and our cells prefer the left-handed version (Thalidomide, a right-handed version, caused birth defects)
Term
Monomer
Definition
Subunit of a more complex molecule
Term
Polymer
Definition
Chains of monomers
Term
Biological macromolecules
Definition
Proteins (polypeptides), carbohydrates, nucleic acids, lipids
Term
Polymerization
Definition
Happens through dehydration synthesis (a condensation reaction), which releases a water molecule
Term
Hydrolysis
Definition
Water reacts with a polymer to release a monomer; reverse of dehydration synthesis
Term
Peptide bond
Definition
Bond between amino acids in proteins; during condensation they form between the carboxyl group of one amino acid and the amino group of the other
Term
Polypeptide
Definition
Another name for a protein; they are flexible (peptide bonds can rotate) and have directionality from amino group to carboxyl group, and side chains (R-groups) extend out from the backbone
Term
N-terminus
Definition
The amino end of an amino acid
Term
C-terminus
Definition
The carboxyl end of an amino acid
Term
Four levels of protein structure
Definition
Primary, secondary, tertiary, quaternary
Term
Primary structure
Definition
Unique sequence of amino acids; helps determine protein structure because of the uniqueness of the R-groups (red blood cells vs. sickles)
Term
Secondary structure
Definition
Results from hydrogen bonding between the carboxyl oxygen of one amino acid and the amino hydrogen of another. The chains must bend to allow this bonding, which results in alpha-helices or beta-pleated sheets (which have directionality in the carboxyl group direction). Which one depends on primary structure. The large number of the hydrogen bonds increases the stability of the polypeptide.
Term
Tertiary structure
Definition
3D shape, determined by R-groups, which can interact with other side chains or with the backbone, causing bends and folds.
Term
Five types of side chain interactions in tertiary structure
Definition
Hydrogen bonding, hydrophobic interactions, van der Waals interactions, covalent (disulfide) bonding, ionic bonding
Term
Hydrogen bonding
Definition
They form between hydrogen atoms and the carbonyl group in the backbone
Term
Hydrophobic interactions
Definition
In water, hydrophilic side chains interact, leaving hydrophobic side chains to coalesce and form hydrogen bonds in globular masses, increasing their stability.
Term
van der Waals interactions
Definition
Weak bonds between hydrophobic side chains, caused by minute partial charges on each
Term
Disulfide bonding
Definition
Bonds between two sulfur-containing R-groups
Term
Ionic bonding (tertiary structure)
Definition
Form between groups with full and opposite charges
Term
Quaternary structure
Definition
Bonding between several polypeptide subunits in a protein
Term
Protein folding
Definition
Makes the protein more energetically stable; often spontaneous because of the hydrogen bonds and van der Waals interactions
Term
Denatured
Definition
An unfolded protein, unable to function normally
Term
Molecular chaperones
Definition
Proteins that help other proteins fold correctly
Term
Antibodies and complement proteins
Definition
Used in defense to destroy disease-causing viruses and bacteria
Term
Contractile and motor proteins
Definition
Used for movement
Term
Enzymes
Definition
Catalyze chemical reactions
Term
Peptide hormones
Definition
Act as signals to help coordinate activities of many cells
Term
Receptor proteins
Definition
Receive chemical signals from outside cell and initiate response
Term
Structural proteins
Definition
Provide support for cells and tissues; form structures such as hair, feathers, cocoons, and spider webs
Term
Transport proteins
Definition
Move substances across the cell membrane and throughout the body
Term
Types of proteins
Definition
Antibodies and complement proteins, contractile and motor proteins, enzymes, peptide hormones, receptor proteins, structural proteins, and transport proteins
Term
Catalysis
Definition
Adding energy to initiate a chemical reaction; important because for early molecules to copy themselves, they would have had to catalyze themselves as well
Term
Activation energy
Definition
Energy added to the kinetic energy of reactants in a chemical reaction to get them to reach the transition state; this is why chemical reactions tend to go faster at higher temperatures
Term
Catalyst
Definition
A substance that lowers the activation energy in a reaction by stabilizing the transition state; they are not consumed in the reaction. They do not, however, change the free energy in the reaction (delta G)
Term
Substrate
Definition
The molecule that is being catalyzed by an enzyme; they are specific to different enzymes
Term
Active site
Definition
Where a substrate binds to an enzyme; the R-groups here help facilitate hydrogen bonding, covalent bonding, and proton transfer with the substrate
Term
Three steps of enzyme action
Definition
Initiation, transition state facilitation, and termination
Term
Initiation
Definition
Reactants bind to the active site
Term
Transition state facilitation
Definition
Interactions between the substrate and active site R-groups lower the activation energy
Term
Termination
Definition
Reaction products are released from the enzyme, as they have a low affinity for the active site
Term
Cofactors
Definition
Things that help enzymes function normally; they can include metal ions or coenzymes
Term
Coenzyme
Definition
Small organic molecules that help enzymes act normally
Term
Methods of enzyme regulation
Definition
Competitive inhibition and regulatory molecules
Term
Competitive inhibition
Definition
Molecules similar to substrates bind to the active site rather than substrates themselves
Term
Regulatory molecules
Definition
Molecules which bind to the enzyme at a location other than the active site and change the shape so the active site is inaccessible
Term
Allosteric regulation
Definition
Regulation which does not affect the active site directly
Term
What limits the rate of catalysis?
Definition
At low substrate concentrations, the catalyst improves the reaction rate linearly, but it plateaus at higher concentrations of substrate. Enzymes with high substrate affinity plateau quicker. This is generally affected by pH and temperature; each enzyme has different optimal temperatures and pH levels.
Term
How does ATP drive endergonic reactions?
Definition
The chemical energy of its phosphate groups (PO4 3-) can split up one endergonic reaction into two exergonic reactions:

Step 1: ATP transfers one of its three phosphate groups to a substrate, giving an active substrate and ADP (exergonic)

Step 2: the active substrate reacts normally. The extra energy from its phosphate group makes the reaction exergonic.
Term
Was the first living entity a protein?
Definition
Probably not; though proteins are efficient catalysts, they do not provide templates for self-replication
Term
Nucleic acid
Definition
Polymers of nucleotides
Term
Nucleotide
Definition
Monomers of nucleic acids, which are each composed of a phosphate group bonded to a pentose to a nitrogeneous base
Term
Ribonucleotides
Definition
Nucleotides whose pentose is ribose (with an oxygen)
Term
Deoxyribonucleotides
Definition
Nucleotides whose pentose is deoxyribose (missing an oxygen)
Term
Nitrogeneous bases
Definition
Adenine, guanine, cytosine, thymine, and uracil
Term
Purines
Definition
Adenine and guanine
Term
Pyrimidines
Definition
Cytosine, uracil (only in ribonucleotides), and thymine (only in deoxyribonucleotides)
Term
Could chemical evolution result in the production of nucleotides?
Definition
Early earth experiments have not yet demonstrated so; pyrimidines are not easily synthesized under early earth conditions, and there would have had to be more common.
Term
Phosphodiester linkage
Definition
Bonds joining nucleotides at the phosphate group on the 5' carbon and the OH group on the 3' carbon. They join when ATP is added (giving each nucleotide two extra phosphate groups).
Term
Why is the nucleotide backbone polar?
Definition
At one end there is an unlinked 5' carbon and at the other there is an unlinked 3' carbon. The nucleotide sequence is written 5' -> 3'
Term
Watson and Crick
Definition
Scientists who drew conclusions about the structure of DNA
Term
DNA structure
Definition
Double helix, with the hydrophilic sugar-phosphate backbone on the outside and the purine-pyrimidine pairs on the inside
Term
Erwin Chargaff
Definition
Scientist who determined the number of purines was equal to the number of pyrimidines, and the number of A equaled the number of T, and similarly for G and C
Term
Rosalind Franklin and Maurice Wilkins
Definition
Using x-ray crystallography, they calculated the distances between groups of atoms in a DNA molecule; three distances (.34 nm, 2 nm, and 3.4 nm) were repeated many times. This implied a repeating structure in DNA, and the pattern of scattering suggested a helical molecule
Term
Complementary base pairs
Definition
A-T (two hydrogen bonds) and G-C (three hydrogen bonds)
Term
Antiparallel
Definition
Strands of DNA run 5' to 3' in one direction and 3' to 5' in the other
Term
Distance between bases in DNA
Definition
.34 nm
Term
Length of one complete DNA helix turn
Definition
3.4 nm
Term
Width of DNA helix
Definition
2.0 nm
Term
Number of rungs in one turn of DNA helix
Definition
10
Term
Information in DNA
Definition
Determined by ordering of nitrogeneous base pairs; this way, each strand serves as a template for replication
Term
DNA replication
Definition
1. Hydrogen bonds between base pairs break, and the helix separates

2. Each strand of DNA serves as a template for the formation of a new strand, according to complementary bases

3. When the new nucleotides are added in complementary order, the structure is restored
Term
Could the first lifeform have been made of DNA?
Definition
of its stability, it is a reliable store of genetic information. However, this also makes it a poor catalyst, so RNA is a more likely candidate
Term
Differences between RNA and DNA
Definition
1. RNA has uracil rather than thymine

2. RNA has ribose rather than deoxyribose--the presence of this oxygen makes it more reactive than DNA
Term
RNA hairpin structure
Definition
Formed because of the folding over of complementary RNA base pairs on the same strand. Sometimes this happens multiple times, or between RNA strands, giving RNA tertiary or quaternary structure and much variability in their properties.
Term
RNA replication
Definition
1. Complementary bases bond to those already on the single strand

2. Eventually they form a full, complementary strand

3. Strands separate, forming two independent molecules
Term
Could the first lifeform have been made of RNA?
Definition
Despite its unstability, RNA could have survived long enough to replicate itself, due partially to its capacity to contain information and partially to its ability to catalyze itself. This has been replicated in laboratory experiments.
Term
Ribozymes
Definition
RNA catalysts, which start the condensation reactions of phosphodiester linkages
Term
Features of life
Definition
Ability to reproduce and metabolize
Term
Properties of carbohydrates
Definition
Chemical formula of (CH2O)n, contain a carbonyl group, several hydroxyl groups, and many C-H bonds
Term
Monosaccharides
Definition
Simple sugars; have varying placement the carbonyl group. Number of carbon atoms can be 3, 5, or six. They are numbered starting at the end closes to the carbonyl group. They also vary in the placement of their OH groups, so that many sugars have the same formula but different structures
Term
Polysaccharides
Definition
Polymers of monosaccharides, which are formed by condensation reactions
Term
Glycosidic linkages
Definition
Bonds between monosaccharides in a polysaccharide; they can form between any two OH groups.
Term
Starch
Definition
Stores plant sugar; monomers are joined by alpha 1,4 linkages, which form a helical shape
Term
Glycogen
Definition
Stores animal sugar; joined by alpha 1,4 linkages; about one of every 10 glucose monomers branches (forms 1,6 bonds)
Term
Amylopectin
Definition
A type of starch; about one of every 30 glucose monomers branches
Term
Amylose
Definition
A type of starch; no branches
Term
Cellulose
Definition
Primary plant cell wall component; polymer of beta glucose linked by alpha 1,4 bonds in a sheet
Term
Chitin
Definition
Polymer of N-acetylglucosamine monomers, in the cell walls of fungi and algae and in insect and crustacean exoskeletons. They flip as they bond in sheets, allowing hydrogen bonds between them.
Term
Alpha glycosidic linkages
Definition
Oxygen between molecules is down
Term
Beta glycosidic linkages
Definition
Oxygen between molecules is up
Term
Peptidoglycan
Definition
Composes bacteria cell walls; made of alternating N-acetyl-muramic acid (M) and N-acetyl-glucosamine (G). Each M monomer is linked to an amino acid chain, which are in turn linked together by peptide bonds
Term
Antibiotics
Definition
Some kill bacteria by disrupting peptide bonds in peptidoglycan, thus weakening their cell walls
Term
Carbohydrate functions
Definition
- Synthesis of other molecules
- Cell protection
- Cell identity
- Store energy
Term
Carbs in cell identity
Definition
Information is displayed on the outside of cells
Term
Glycoproteins
Definition
Proteins on the outside of cell which have covalently bonded to carbohydrates and give identifying information about the cell
Term
Carbs as electron donors
Definition
When they are formed (usually through photosynthesis), energy is stored in C-H bonds; this means they have extra electrons to give in the form of ATP, which drives endergonic reactions and does cell work
Term
Plasma membrane
Definition
Layer of molecules (mostly lipids) surrounding a cell that regulates internal environment and passage of molecules in and out of the cell. The development of a plasma membrane around a self-replicator created the first cell
Term
Lipid
Definition
Has a major hydrocarbon component; mostly nonpolar and hydrophobic
Term
Fatty acid
Definition
A hydrocarbon chain bonded to a carboxyl (COOH) group; a key building block for lipid synthesis in organisms
Term
Three types of cellular lipids
Definition
Steroids, phospholipids, and fat
Term
Phospholipids
Definition
3-carbon glycerol linked to a phosphate group and two isoprene chains or fatty acids. The chains are nonpolar and hydrophobic, but the head is polar and hydrophilic because of its oxygen.
Term
Steroids
Definition
Four-ring structure made of isoprene subunits
Term
Fat
Definition
Tryglycerol or triglyceride; a glycerol linked to three fatty acids
Term
Ester linkages
Definition
Formed by condensation reactions between glycerol hydroxyl groups and fatty acid carboxyl groups
Term
Amphipathic
Definition
They have a hydrophobic central region and a hydrophilic outer region (phospholipids)
Term
Phospholipid bilayer
Definition
Polar heads out, so they can interact with the water in our bodies and inside the cells
Term
Permeability
Definition
Ability for things to travel in and out of the membrane
Term
Selective permeability of lipid bilayers
Definition
Small and nonpolar molecules move easily across, but large or polar molecules cross slowly, if at all. The correct ion concentration is maintained by special proteins embedded in the layer.
Term
Partial hydrogenation
Definition
when unsaturated fats are manually resaturated with hydrogen (like in peanut butter, so the oil will be solid & easier to spread). This is less healthy, though.
Term
No unsaturated fatty acids
Definition
Lower permeability because they are packed tightly together, so they are solids at room temperature
Term
Many unsaturated fatty acids
Definition
More permeable, liquid at room temperature
Term
Diffusion
Definition
Movement of molecules from an area of higher concentration to an area of lower concentration; ions and large molecules would not diffuse
Term
Concentration gradient
Definition
The direction molecules in solution should move
Term
Osmosis
Definition
Movement of water in the same fashion as diffusion, but when the solutes cannot move themselves
Term
Hypertonic
Definition
When the outside solution has greater solute concentration than inside; water goes out of the cell; could shrink the cells
Term
Hypotonic
Definition
When the outside solution has less solute concentration than the inside; water goes into the cell; could burst the cells through lysis
Term
Isotonic
Definition
Solute concentrations are equal
Term
Protein (review)
Definition
Monomer: amino acid
Bond: peptide bond
Reaction: condensation
Term
Carbohydrates (review)
Definition
Monomer: monosaccharide
Bond: glycosidic linkage
Reaction: condensation
Term
Nucleic acids (review)
Definition
Monomer: nucleotide
Bond: hydrogen (between bases), phosphodiester linkages (on backbone)
Reaction: condensation
Term
Lipids (review)
Definition
Monomer: fatty acids (long chains) and isoprenes (short)
Bond: ester linkages
Reaction: condensation
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