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• All organisms consists of one or more cells • A cell is the smallest unit with the properties of life • Each new cell arises from division of another, preexisting cell • Each cell passes its hereditary material to its offspring |
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In 1839, Schleiden and Schwann proposed the basic concepts of the modern ___________. |
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the first to describe small organisms seen through a microscope, which he called animalcules and beasties |
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the first to sketch and name cells |
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The smallest unit that shows the properties of life |
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Cell interior is divided into functional compartments, including a nucleus |
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Small, simple cells without a nucleus |
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Controls substances passing in and out of the cell |
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A semifluid mixture containing cell components |
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A double layer of phospholipids organized with their hydrophilic heads outwards and their hydrophobic tails inwards |
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Bacteria and archaea are _________ (“before the nucleus”), the smallest and most metabolically diverse forms of life |
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surrounds the plasma membrane |
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_________ (“true nucleus”) cells carry out much of their metabolism inside membrane-enclosed organelles |
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A structure that carries out a specialized function within a cell |
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• Two lipid bilayers pressed together as a single membrane surrounding the nucleus • Outer bilayer is continuous with the ER • Nuclear pores allow certain substances to pass through the membrane |
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Viscous fluid inside the nuclear envelope, similar to cytoplasm |
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A dense region in the nucleus where subunits of ribosomes are assembled from proteins and RNA |
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All DNA and its associated proteins in the nucleus |
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• A single DNA molecule with its attached proteins • During cell division, chromosomes condense and become visible in micrographs • Human body cells have 46 chromosomes |
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• A series of interacting organelles between the nucleus and the plasma membrane • Makes lipids, enzymes, and proteins for secretion or insertion into cell membranes • Other specialized cell functions |
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Endoplasmic reticulum (ER) |
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An extension of the nuclear envelope that forms a continuous, folded compartment |
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folds polypeptides into their tertiary form |
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makes lipids, breaks down carbohydrates and lipids, detoxifies poisons |
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Small, membrane-enclosed saclike organelles that store or transport substances |
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Vesicles containing enzymes that break down hydrogen peroxide, alcohol, and other toxins |
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Vesicles for waste disposal |
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• A folded membrane containing enzymes that finish polypeptides and lipids delivered by the ER • Packages finished products in vesicles that carry them to the plasma membrane or to lysosomes |
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Vesicles containing enzymes that fuse with vacuoles and digest waste materials |
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• Eukaryotic organelle that makes the energy molecule ATP through aerobic respiration • Contains two membranes, forming inner and outer compartments; buildup of hydrogen ions in the outer compartment drives ATP synthesis • Has its own DNA and ribosomes • Resembles bacteria; may have evolved through endosymbiosis |
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Organelles that function in photosynthesis or storage in plants and algae; includes chromoplasts, amyloplasts, and chloroplasts |
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• Plastids specialized for photosynthesis • Resemble photosynthetic bacteria; may have evolved by endosymbiosis |
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• A plant organelle that occupies 50 to 90 percent of a cell’s interior • Stores amino acids, sugars, ions, wastes, toxins • Fluid pressure keeps plant cells firm |
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A thin, pliable wall formed by secretion of cellulose into the coating around young plant cells |
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A strong wall composed of lignin, formed in some plant stems and roots after maturity |
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Extracellular matrix (ECM) |
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A nonliving, complex mixture of fibrous proteins and polysaccharides secreted by and surrounding cells; structure and function varies with the type of tissue • Example: Bone is mostly ECM, composed of collagen (fibrous protein) and hardened by mineral deposits |
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A bone cell surrounded by extracellular matrix |
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_________ ____________ allow cells to interact with each other and the environment |
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In plants, ______________ extend through cell walls to connect the cytoplasm of two cells |
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tight junctions, adhering junctions, gap junctions |
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three types of cell junctions |
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• An interconnected system of many protein filaments – some permanent, some temporary • Parts of the cytoskeleton reinforce, organize, and move cell structures, or even a whole cell |
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• Long, hollow cylinders made of tubulin • Form dynamic scaffolding for cell processes |
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• Consist mainly of the globular protein actin • Make up the cell cortex |
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Maintain cell and tissue structures |
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• Accessory proteins that move molecules through cells on tracks of microtubules and microfilaments • Energized by ATP • Example: kinesins |
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Eukaryotic flagella and cilia |
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• Whiplike structures formed from microtubules organized into 9 + 2 arrays • Grow from a centriole which remains in the cytoplasm as a basal body |
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“False feet” used by amoebas and other eukaryotic cells to move or engulf prey |
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___________ _____________ regulate the movement of substances in and out of cells |
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• Describes the organization of cell membranes • Phospholipids drift and move like a fluid • The bilayer is a mosaic mixture of phospholipids, steroids, proteins, and other molecules |
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• The ability of a cell membrane to control which substances and how much of them enter or leave the cell • Allows the cell to maintain a difference between its internal environment and extracellular fluid • Supplies the cell with nutrients, removes wastes, and maintains volume and pH |
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The number of molecules (or ions) of substance per unit volume of fluid |
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• The difference in concentration between two adjacent regions • Molecules move from a region of higher concentration to one of lower concentration |
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• The net movement of molecules down a concentration gradient • Moves substances into, through, and out of cells • A substance diffuses in a direction set by its own concentration gradient, not by the gradients of other solutes around it |
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1) Size 2) Temperature 3) Steepness of the concentration gradient 4) Charge 5) Pressure |
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Rate of diffusion depends on what five factors? |
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Passive transport (facilitated diffusion) |
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• Requires no energy input • A passive transport protein allows a specific solute (such as glucose) to follow its concentration gradient across a membrane • A gated passive transporter changes shape when a specific molecule binds to it |
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• Requires energy input (usually ATP) • Moves a solute against its concentration gradient, to the concentrated side of the membrane |
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Active transporters move calcium ions across muscle cell membranes into the sarcoplasmic reticulum |
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• An active transport protein that moves two substances across a membrane at the same time • Example: The sodium-potassium pump moves Na + out of the cell and K + into the cell |
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Formation and movement of vesicles formed from membranes, involving motor proteins and ATP |
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The fusion of a vesicle with the cell membrane, releasing its contents to the surroundings |
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The formation of a vesicle from cell membrane, enclosing materials near the cell surface and bringing them into the cell |
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Extracellular fluid is captured in a vesicle and brought into the cell; the reverse of exocytosis |
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Receptor-mediated endocytosis |
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Specific molecules bind to surface receptors, which are then enclosed in an endocytic vesicle |
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Pseudopods engulf target particle and merge as a vesicle, which fuses with a lysosome in the cell |
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The movement of water down its concentration gradient – through a selectively permeable membrane from a region of lower solute concentration to a region of higher solute concentration |
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The relative concentrations of solutes in two fluids separated by a selectively permeable membrane |
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For two fluids separated by a semipermeable membrane, the one with lower solute concentration is __________, and the one with higher solute concentration is __________ • Water diffuses from hypotonic to hypertonic |
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fluids have the same solute concentration |
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Hydrostatic pressure (turgor) |
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The pressure exerted by a volume of fluid against a surrounding structure (membrane, tube, or cell wall) which resists volume change |
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The amount of hydrostatic pressure that can stop water from diffusing into cytoplasmic fluid or other hypertonic solutions |
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Which values sound reasonable for a healthy, 80 kilogram resting adult? |
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a: 108,000 heart beats per day b: About 5.25 liters of blood are pumped per minute |
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During early ventricular systole the atria are in |
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The embryo heart actually begins working before its development is complete. |
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How many half-moon shaped, pocketlike semilunar cusps are found in each semilunar valve? |
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The chordae tendineae are made out of |
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The inferior chambers of the heart are the |
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The right and left coronary arteries are the only branches of the ascending aorta. |
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Of the four "normal" heart sounds, the initial "lubb" is when the |
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The gap junctions of intercalated discs provide a low-resistance pathway across the membranes of adjoining cardiac muscle fibers. |
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For ___________ of the cardiac cycle, all four chambers are in diastole together. |
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Most of the interventricular septum is supplied by the |
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anterior interventricular artery |
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Which direction correctly fits the placement of the heart's apex? |
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One of the reasons that necessitates the relatively early development of the heart is that the embryo has become too large to receive adequate nutrient supply by diffusion alone. |
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Some seventy percent of the ventricle filling is achieved passively without the contraction of the atria. |
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Which action causes the closure of the right atrioventricular valve? |
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contraction of the right ventricle |
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The cell-to-cell contacts of the cardiac muscle fibers are called |
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Pectinate muscles are found on the |
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anterior wall of the right and left tria |
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The internal wall surface of each ventricle displays large, smooth, irregular muscular ridges called the |
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The papillary muscles attach to the cusps of the atrioventricular valves by means of the |
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Development of the heart commences in the _______ week. |
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During ventricular systole |
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Like the right atrium, the left atrium also has pectinate muscles along its anterior wall. |
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It is the _____________ that permits the compression necessary to pump large volumes of blood out of the ventricles. |
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arrangement of cardiac muscle in the heart |
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The embryo heart actually begins working before its development is complete. |
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The trabeculae carneae in the left ventricle are ____________ in the right ventricle. |
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Which are functions performed by the fibrous skeleton of the heart? |
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a: Separates the atria and ventricles b: Anchors the heart valves c: Provides electrical insulation between the atria and ventricles d: Provides the framework for the attachment of the myocardium |
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Though the autonomic innervation by autonomic centers in the brainstem cannot initiate a heartbeat, it can increase or decrease the heartbeat. |
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The papillary muscles attach to the cusps of the atrioventricular valves by means of the |
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Which analogy fits the human heart? |
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It is like a double pump, each working side by side with the other |
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The abnormal impulses that lead to premature ventricular contraction originate in the |
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Which helps describe the endocardium? |
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a: Has single layer of epithelium b: Has layer of areolar connective tissue c: Epithelial cells are squamous |
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During ventricular contraction the semilunar valves close in order to permit the blood to enter the large arterial trunks that carry blood away from the heart. |
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During early ventricular systole the atria are in |
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The beginning of the cardiac cycle is when the |
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function as a coordinated single unit. |
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The arteries and veins that leave and enter the heart are called great vessels because |
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they have relatively large diameters. |
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As blood is pumped into the arterial trunks past the semilunar valves, it |
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pushes against the cusps, forcing the valves open |
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Which valve prevents the backflow of blood into the left ventricle when the ventricles relax? |
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Parasympathetic innervation of the heart travels to the heart via |
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What part of the cardiac conduction system is located in the posterior wall of the right atrium, adjacent to the entrance of the superior vena cava? |
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Which pair is located more anteriorly for the usually placed heart? |
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Right atrium and right ventricle |
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All cardiac veins eventually drain into the coronary sinus for return of the blood from the myocardium to the right atrium. |
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During ventricular systole |
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the semilunar valves open and the AV valves close. |
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One of the reasons that necessitates the relatively early development of the heart is that the embryo has become too large to receive adequate nutrient supply by diffusion alone. |
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It is the contraction of the atria during atrial systole that completes the filling of the ventricles while the ventricles are in diastole. |
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The function of the coronary sinus is to |
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take blood from the heart muscle tissue to the right atrium. |
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Which of the cardiovascular system's circuit has deoxygenated blood in its arteries? |
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The foramen ovale is actually an opening in the |
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The papillary muscles attach to the cusps of the atrioventricular valves by means of the |
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Like the right atrium, the left atrium also has pectinate muscles along its anterior wall. |
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The right border of the heart is supplied by the |
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The layer of the heart wall composed of cardiac muscle tissue is the |
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Which bears a close structural relationship with the fossa ovalis? |
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The serous fluid within the pericardial cavity works to |
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lubricate the membranes of the serous pericardium. |
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No matter the cause, hypertrophy of the heart causes it to work less efficiently. |
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All cardiac veins eventually drain into the coronary sinus for return of the blood from the myocardium to the right atrium. |
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The atria are separated from the ventricles externally by the |
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