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BIO 1107 Chap 7
Cellular Energy
49
Biology
Undergraduate 1
09/22/2024

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Term
What is energy?
Definition
the capacity to cause change or the ability to do work
Term
What are the different types of energy?
Definition
  • Kinetic- things in motion
  • Potential- stored energy with "potential" to cause change
  • Thermal- heat
  • Chemical- energy stored in chemical bonds
Term
What are the Laws of Thermodynamics
Definition
  1. Energy cannot be created or destroyed. It can be converted from one type to another
  2. Every time energy is converted, useful energy is lost
Term
Cell energy usage/ conversion
Definition
the cell uses glucose as its source of chemical energy- combust it with oxygen and you get energy to perform cellular processes
Term
What is Gibbs Energy (G)
Definition
describes molecules and scenarious
Term
In High G....
Definition
the system has a lot of energy, is pretty unstable, and reacts readily. The reaction proceeds and the G goes down until the system becomes stable and less work can be done
Term
Gibbs Free Energy
Definition
the potential that can be used to calculate the amount of work that can be done
Term
Delta G can be used to determine.....
Definition
if a chemical reaction is going to release or absorb energy
Term
ΔG=0
Definition

the system in in equilibrium and energy will not be released or absorbed

  • a stable system and the forward and reverse reaction is going to happen at equal rates
Term
ΔG<0 or negative
Definition

the reaction will happen spontaneously and release energy

  • less free energy at the end of the reaction
Term
ΔG>0 aka positive
Definition

the reaction will not occur unless there is an input of energy

  • work has to be done to get the reaction to go
  • products have a high free energy
Term
Exergonic reactions
Definition
  • release energy
  • will happen spontaneously
  • have a negative ΔG
  • ex: cellular respiration
Term
How is Cellular Respiration and example of Exergonic Reaction
Definition
glucose reacts with oxygen to release CO2, water, and energy. The energy of the products is less than the energy of the reactants
Term
Endergonic Reaction
Definition
  • absorbs energy
  • will not happen spontaneously unless energy is put into the system
  • has a positive ΔG
  • ex: photosynthesis
  • energy in products is greater than reactants
Term
how is photosynthesis an example of Endergonic Reactions
Definition
  • energy from the sun is put into CO2 and water to create glucose and oxygen
Term
What is a closed system Chemical Reaction
Definition

the reaction will continue until it reaches equilibrium

  • not always useful
Term
Cells are not a closed system why?
Definition
because they need reaction to keep happening for energy
Term
How do you have an open system in reactions
Definition

removing the products allows reactions to keep happening, but by removing the products more reactants are used and more energy is produced

 

Term
Chemical Energy
Definition

energy contained in molecules and is released in chemical reactions

-a way to store things that are easily accessible

ATP

Term
Bioenergetics
Definition
the study of how energy flows through living organisms
Term
What is Metabolism
Definition

the total of all the chemical reaction in an organism

-all the reactions dont happen at ones

Term
Metabolic pathway
Definition
the coordination of multiple reaction of one after another in a flow
Term
In a metabolic pathway, each step is catalyzed by a protein called an
Definition
enzyme
Term
Catabolism
Definition

the breaking of molecules to release energy (cellular respiration)

+ΔG

Term
Anabolism
Definition

the consumption of energy to build molecules, frequently large ones (photosynthesis)

-ΔG

Term
What is reaction coupling?
Definition

release energy by breaking a bond and take this energy to use it for an endergonic reaction 

net -ΔG so the system will run

Term
What is ATP
Definition
  • Adenosine Triphosphate
  • the main energy carrier in the cell
  • an adenosine nitrogen ring attached to 3 phosphate groups
  • the bond between the final two phosphate groups stores a lot of chemical energy
Term
Phosphorylation
Definition

the transfer of phosphate groups

- the process is catalyzed by enzymes

Term
What are ways to use ATP
Definition
  • muscle- the motor protein
  • active transport- ATP forces things to go against concentration gradient
  • chemical reactions
Term
ATP is not the only energy carriers in the cell. there are electron carriers. Why?
Definition
free electron can be destructive, so you need a place to put them until they are needed
Term
What are the two electron carriers
Definition
NADH and FADH2
Term
What are they two electron carries that deliver electrons to a reaction
Definition
NADH and FADH2
Term
What are they two electron carries that accept electrons
Definition
NAD+ and FADH
Term
Catalysts
Definition

molecules that accelerate reactions with a -ΔG by lowering activation energy

  • speeds up only exergonic reactions
  • not consumed or changed by the process
Term
What is activation energy
Definition
the minimum amount of energy required to cause a process to occur
Term
different reactions have different amounts of activation energy required so that means that
Definition
  • those that need a lot of activation energy progress slowly until a catalyst is added
Term
There are two types of catalysts
Definition
  • inorganic- unregulated
  • enzymes- proteins- regulated
Term
What are properties of enzymes that make them better in living systems
Definition
  1. very specific for the reactions the catalyze
  2. their activity can be, and is, tightly regulated
Term
Shape= function
Definition
if you change an enzymes shape it will no longer catalyze anything
Term
the active site
Definition

is the place in the enzyme where catalysis actually occurs

  • where subtrates bind, reaction is catalyzed, and products are released
Term

What is the catalytic cycle

 

Definition
  1. the active site is open and substrates bind
  2. the reactivation energy is lowered, and the reaction is catalyzed and proceeds and products are formed
  3. the products are released, and the enzyme is in the exact same state as it was in the beginning, ready to do the process again
Term
What is the downside of enzymes
Definition
  • they are very sensitive to the environment and changes
  • if a cell finds itself out of the ranges the enzyme will not be functional and this can be lethal for the cell
Term
How do we regulate enzymes?
Definition
whether they are made at all and their shape/ function
Term
what is enzyme synthesis
Definition
genes that code for specific proteins are turned on and off according to the cell's changing need
Term
What are the three types of regulation
Definition
  • allosteric
  • competitive or noncompetitive
  • feedback inhibition
Term
Allosteric Regulation
Definition

regulation via controlled changes in molecular shape

  • these chape changes are caused by inhibitors or activators
  • a regulation site, is away from the active site, allows inhibitors to bind causing shape to change to either inhibit or activate the enzyme
Term
Competitive Inhibition
Definition
the inhibitor actually binds to the active site. the inhibitor is shaped very similar to the regular substrates it fits int he pockets
Term
Noncompetitive Inhibition
Definition
the inhibitor binds somewhere else to the enzyme to cause shape change of the active site so that it can no longer bind substrate
Term
Feedback inhibition
Definition

the final product will go back and act as an inhibitor to an enzyme for an earlier step

(negative feedback)

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