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BIO 1107 Chap 13
Mendelian Extensions
36
Biology
Undergraduate 1
11/12/2024

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Term
What assumptions did Mendel make that the pea plants follow?
Definition
  1. Each trait is controlled by a single gene
  2. One allele is completely dominant over the other
  3. Only two possible alleles or exist for a gene
Term
How do we get different alleles?
Definition
through genetic mutations
Term
What are mutations
Definition
Changes in genetic sequence
Term
When mutations change the genetic sequence, what do they produce?
Definition
produce proteins which give different alleles
Term
What is the wild type
Definition
the prevalent allele in the population
Term
What is a mutant
Definition
the changed gene
Term
True or false: the dominant trait are the more prevalent
Definition
false
Term
What are some examples of the dominant trait that are NOT the most common in the population
Definition
  • Polydactyl (more than 5 digits)
  • Achondroplasia (dwarfism)
  • Widows peakĀ 
Term
What are polygenic traits
Definition
traits that are controlled by more than one gene
Term
what's an example of a polygenic trait
Definition
height, skin color, eye color
Term
What is incomplete Dominance
Definition

the heterozygote exhibits an intermittent phenotype

- results in more than 2 alleles in the population

Term
What is the incomplete dominance phenotypic ration
Definition
1:2:1
Term
What is the incomplete dominance genotypic ratio? Why?
Definition

1:2:1

because the genotype is directly reflected by the phenotype

Term
What's an example of incomplete dominance in human
Definition
hair texture
Term
What is Codominance?
Definition
Heterozygous individuals express both phenotypes equally
Term
What's an example of Codominance in Humans?
Definition
Blood Type
Term
What blood type is the example of Codominance
Definition

AB

- Heterozygous individuals express both the A sugar and the B sugar and so both are produced, and you get the Ab blook type

Term
What is the recessive blood type and what sugars are on it
Definition
type O- it has no sugars
Term
What is the genotypic and phenotypic ratio in codominance
Definition
1:2:1
Term
What is Pleiotropy
Definition
the activity of one gene produces multiple phenotypes in the organism
Term
What is an example of pleiotropy in humans and what phenotypes does it affect
Definition
albinism
It affects the hair, skin, blue eyes
Term
What is Polygenic traits
Definition
where more than one gene contributes to a phenotype
Term
Epistasis is
Definition
one gene masks the phenotypic effect of the other
Term
In epistasis both genes...
Definition
must be working to get a particular phenotype
Term
The X chromosomes is
Definition
very large and has many genes
Term
Since men only have one X chromosomes that makes them
Definition
hemizygous
Term
Men not having an X chromosome can greatly affect
Definition
the inheritance of genes on the X chromosomes
Term
Autosomal dominance tends to affect
Definition
every generation and both genders equally
Term
X- linked inheritance is recessive so it
Definition
tends to skip a generation and the reemerge
Term
The environment can affect
Definition
gene expression and phenotype
Term
what are temperature sensitive
Definition
enzymes
Term
What are ways we can do gene testing
Definition
in utero testing
Term
what are the three in utero tests
Definition
-amniocentesis
-chorionic villus Sampling
-blood test
Term
What is Amniocentesis
Definition
an ultrasound needle is pushed through the stomach into the uterus and draws out fluid that contain fetal cells and DNA
- only problem is it cannot be done till 16 weeks
Term
What is chronic villus sampling
Definition
the placenta is sampled through the cervix
Term
Why is blood drawing the best option for in utero testing
Definition
its noninvasive and can be done when the pregnancy is only a few weeks old
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