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BIO 1107 Chap 12
mendelian Genetics
50
Biology
Undergraduate 1
11/09/2024

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Term
Who was Gregor Mendel?
Definition
He was an Austrian monk that worked with pea plants
Term
Who was Mendel referred as and why?
Definition
"Father of Genetics" for his great contributions to the field of inheritance
Term
What was ironic about Mendel discovering Genetics
Definition
he was not a biologist, he was a statistician
Term
Why did Mendel succeed when biologist failed?
Definition
he chose a good model organism
Term
What was Mendel's organism and what attributes made it a good model?
Definition

a pea plant

  • really easy to grow
  • has true breeding strains
  • easily control matings to eliminate variables
  • grows to maturity in one season
  • easily observable characteristics
Term
What is a gene
Definition

a unit of heredity that is passed from parent to offspring

- it is the actual trait

ex: petal color

Term
What is an allele
Definition

"one or two or more forms of a gene"

- what a trait looks like

ex: purple or white

Term
Why do alleles occur?
Definition
because the genetic sequence between one member of a homologous pair is not identical to the sequence in the other chromosome
Term
What is a genotype
Definition

the genetic makeup of a given organism

-the gene, the nucleotide sequence

Term
What is the phenotype of
Definition

the physical manifestation of a gene

- what the gene looks like

Term
What does genotype arise from
Definition
the gene
Term
What does the phenotype arise from
Definition
the allele
Term
what was the design flow of Mendel's experiment
Definition
monohybrid cross of the parent generation-> self-fertilization-> asses
Term
What is a monohybrid cross
Definition
a single gene cross between two heterozygotes
Term
What is true breeding?
Definition
parents produce offspring with the same phenotype. ALWAYS
Term
What is the Parental Generation (P)
Definition
- mating two true breeding pea plants together
Term
what are the offspring of the parental generation called?
Definition
the F1 generation
Term
What is it called if you self-fertilize the F1 generation
Definition
the F2 generation
Term
Why wouldn't Mendel's experiment work in humans
Definition
  • cant control who breeds with who
  • cant self- fertilize a human or mate with the same generation- would run into disorders
  • too many variables to track
Term
What did Mendel call genes?
Definition
single factors
Term
what did Mendel see when he studied one gene (petal color) with two alleles (purple or white allele)
Definition

P: true- breeding purple with true breeding white

F1: all purple

F2: 3/4 purple, 1/4 white (3:1 ratio)

Term
Wdid just looking at one gene at a time work
Definition
because the genes were not sex- dependent so the colors could have come from the male parent or the female parent
Term
What were the three postulate that Mendel made
Definition
  1. Unit factors (alleles) exist in pairs
  2. In the pair, one allele is dominant, and one is recessive
  3. the paired unites segregate independently during gamete formation
Term
Pea plants are diploid organisms, so when you are describing the genotype..
Definition
you describe the gene that is on each one of the homologous pairs
Term
What is homozygous
Definition
if the allele is said to be on both chromosomes
Term
homozygous dominant
Definition
are both the dominant allele
Term
homozygous recessive
Definition
if the genes are both the recessive allele
Term
heterozygous
Definition
if the individual has a different allele on each chromosome
Term
What is dominant
Definition

the allele that masks the appearance of the other alleles

ex: if you have one copy of that dominant allele, that is the phenotype you see

 

Term
homozygous dominant or heterozygous individuals will always show
Definition
the dominant phenotype
Term
What is recessive
Definition
the allele that is masked by the dominant allele
Term
In order for a recessive allele to be seen
Definition
you must have two copies (homozygous recessive) of the recessive allele in order to see the phenotype
Term
What does dominacne NOT mean
Definition
the frequency in the population
Term
What is Mendel's first law
Definition
Law of Segregation
Term
What does the law of segregation mean
Definition
pairs of alleles separate independently of each other in gametes
Term
What is the genotypic ration of a monohybrid cross of Ppx Pp
Definition
a 1:2:1 because it describes the frequencies of the different genotypes
Term
What is the phenotypic ration of a monohybrid cross of Pp x Pp
Definition
3:1
Term
If you have an organism that has the dominant phenotype showing, how would you know their genotype?
Definition
by doing a Test Cross
Term
What is a test cross
Definition
drawing the Punnett square for watch of the two possible crosses and see which outcome predicted matches you experimental outcome
Term
What is a dihybrid cross
Definition
looking at two traits with a possibility of 4 alleles
Term
What is Mendel's Dihybrid ration
Definition
9:3:3:1
Term
What is the Law of Independent Assortment
Definition

genes separate and are inherited INDEPENDENTLY of one another

ex: pea color has no effect on pea shape

Term
How is all of this useful
Definition
WE can make prediction of the results of various crosses and compare that to experimental data to see if we are correct or not
Term
What is probability
Definition
the predicted outcome of a processes, it can be expressed as a ratio or a percentage
Term
What is the Sum law
Definition

the probability of a generalize outcome that can be accomplished in more than one way. the trigger word is OR

-the probability increases from the dingle event

Term
What is the product Law
Definition

the probability of two events occurring at the same time. The big trigger word is AND

- the probability goes way down because two things happening simultaneously is a lot harder to accomplish than two things occurring in multiple possible ways

Term
What are pedigrees
Definition
charts that track the occurrence of a given phenotype throughout the generations of a family
Term
What can pedigrees provide
Definition

clues as to the mechanism of inheritance

ex: is the trait dominant or recessive

Term
true or false: dominant are observed on every generation in both genders in pedigrees
Definition
true
Term
in pedigrees, recessive traits are observed to
Definition
skip a generation and the reappear and affect both genders
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