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What are the function of Hormones? |
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Regulate: Growth Metabolism Reproduction Behavior |
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What are target cells or tissue? |
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The specific tissue acted on by a hormone |
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How are hormone levels regulated? |
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Hormones are regulated by other hormones. |
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What are the other hormone producing tissues? |
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Stomach- secretes hormone that stimulates digestion. Kidney Heart- produces hormone that affects blood pressure and sodium levels -placenta- produces human growth hormone |
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How are some hormones used for treatment? |
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Hormonal therapy of cancer
Aging Hormone replacement therapy (menopause) connected to menopause. Testosterone replacement in males with low levels due to disease or aging
Thyroid hormone replacement |
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The hypothalamus is responsible for certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, thirst,fatigue, sleep, and circadian cycles. |
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2 parts- anterior and posterior Master gland- it releases hormones that control other glands. Hormones: Growth hormone (GH) growth or repair. Thyroid stimulating hormone (TSH) stimulate thyroid gland to produce T3 and T4. Adrenocorticotropic hormone (ACTH) -Tropin/tropic means stimulating -stimulates the cortex of the adrenal gland. Prolactin (PRL) -stimulates the production of milk in women. Gonadotropins: Follicle-stimulating hormone (FSH) stimulates the development of eggs and sperm. -Lueteinizing hormone (LH) Causes ovulation in females in males it causes the release of testosterone.
Posterior Pituitary hormones: Antidiurectic hormone (ADH) promotes re-absorption of water. Decreases urine output. Oxytocin: Causes contraction of the uterus during childbirth causes ejection of milk from the breast. |
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Found in the Diencephalon - produces melatonin -mainly produced during the dark time of the day. influences your sleep\wake cycles. |
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- Largest of the endocrine glands - located in the neck - Thyroid hormones: Thyroxine (T4) and trilodothyronine (t5) -Major metabolic hormones - Increase protein and glucose metabolism. Calcitonin: -stimulates the increase of calcium storage in the bone. -Decreases levels of calcium in the blood. |
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Small glands, embedded in back side of thyroid gland. Secrets Parathyroid hormone (PTH) regulates calcium levels in the blood. Has the opposite effect as calcitonin Promotes release of calcium from bone increases amount circulating in blood. |
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Located under sternum above the heart (mediastinem Membrane) -important for immune system development -releases thymosin |
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produce hormone stimulates red blood cell production. |
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Small, pyramid-shaped glands that sit above each kidney made up of 2 parts that are both different in structure and function inner area- medulla outer area- cortex
Medulla- has nervous system control released in response to sympathetic nervous system main hormone epinephrine (also called adrenaline) Also norepinephrine is also released Both are called the fight or flight hormones because of their effect during emergency situations. |
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Part of the pancreas is made up of small groups of specialized cells that produce hormones the groups of cells are called islets of langerhans |
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Male hormones promote the development of sexual characteristics. Maturity of sexual organs Appearance of secondary sexual characteristics Secretes testosterone |
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female hormones promote the development of sexual characteristics. Maturity of sexual organs Secretes estrogen Progesterone Appearance of secondary sexual characteristics |
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Caused by hypersecretion of thyroxine Goiter Bulging eyes Very nervous Abnormal fast metabolism |
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Creatinism (children) and Myxedema (adults) |
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- Caused by hyposecretion of thyroxine - in children causes lack of physical and mental development - in adult causes sluggish mental and physical capabilities - overweight and cold |
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Caused by hypofunction of cortex Characterized by miscle atrophy, weakness, and salt and water imbalance |
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Caused by hypersecretion of cortex Trunk obesity, think skin easily bruised, weakness,bone loss, buffalo hump |
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2 hormones produced by pancreas islets are: |
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Insulin- Aids in transport of glucose from outside cells to inside cells where it can be used for energy. Glucagon Causes liver to release stored glucose from cells into the bloodstream. it increases blood sugar levels. |
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Caused when insulin is not produce or is not effective Type I- insulin-dependent diabetes -less common, but more severe -Autoimmune disorder in which the cells that produce insulin are attacked by the immune system.
Type II non-insulin-dependent diabetes Commonly occurs in overweight adults Most still produce insulin but the body does not respond as it should Can be controlled by medication, diet, exercise, and weight loss. |
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Transportation Regulation- Buffers in the blood regulate the pH of the fluid, keeping it about 7.4. Also regulated the amount of fluid in the tissues by controlling osmotic pressure. Also regulates body temperature Protection- Protects against infection. - Carries immune system cells and antibodies. - Coagulants makes scabs. |
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What is the composition of blood? |
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Liquid portion- plasma Formed elements- cells and fragments Erythrocytes-red blood cells Transport oxygen leukocytes- white blood cells - fight infect Platelets- thrombocytes -cell fragments that play role in blood clotting. |
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Platelets function to stop______? |
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Types of WBCs and their functions. |
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Granulocytes: Neutrophils- Phagocytosis Eosinophils- Allergic reactions, defense against parasites Basophils- allergic reactions, inflammatory reactions. Agranulocytes: Lyphocytes- Immunity (T cells and B cells) Monocytes- Phagocytosis |
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Function and composition of RBCs |
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Oxygenates organs, carries nutrients, Hemoglobin- a protein that contains iron. erythropoietin or (EPO) hormone that stimulates the production of RBCs. |
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Where are formed elements of blood formed? |
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They are produced in red bone marrow which is located in the ends of long bones and in the inner mass of all other bones. |
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What is Hemostasis and how is it accomplished. |
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Is the process that prevents blood loss from the circulation when blood vessel is ruptured by and injury. 1. Contraction: of the smooth muscles in the blood vessel wall. 2. Formation: of a platelet plug. Activated platelets become sticky and adhere to the defect to form a temporary plug. 3. Formation: of a blood clot (Coagulation) |
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How are blood types determined? |
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Type refers to the type of antigen present on the red cells. 1. If only the A antigen is present the person is A. 2. If only the B antigen is present the person is a B type. 3. If both A and B antigens are present then AB type. 4. If neither A nor B antigens are present then person is type O. |
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What are blood and its components used for? |
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Plasma- used to replace blood volume and prevent circulatory failure. |
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important for maintaining osmotic pressure of the blood clotting factors- necessary for blood coagulation Antibodies- fight infection |
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enzymes that aid antibodies in fighting infection |
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Glucose, amino acids, lipids, electrolytes- choloride, carbonate, sodium, potassium and calcium
Vitamins, hormones, waste products and drugs. |
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Tiny disk-shaped cells that are concave in the middle they don't have a nucleus the are anaerobic function using lactic acid |
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process when wbc squeezes out the blood cells into other tissues |
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Made up of cell fragments smallest of formed elements cause coagulation when they are exposed to anything other than the lining of blood vessles they stick together and form clots. |
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process prevents loss of blood. Constricts blood vessel forms a platelet plug thrombin converts fibrinogen to solid threads of fibrin and they form a sticky clot. |
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fluid that remains after blood is clotted |
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iron is an essential part of hemoglobin |
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caused by deficiency of vit b 12 |
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excessive production of wbcs due to cancer |
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cancer of the lymphoid tissue |
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disseminated intravascular coagulation |
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excessive clotting due to tissue damage |
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measures the percentage of packed red cells in whole blood sample |
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endocardium-thin inner membrane myocardium- thick muscular layer Epicardium- thin outer layer (visceral membrane) |
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pumps blood low in o2 to the lungs through the pulmonary circuit |
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pumps oxygenated blood to the remainder of the body through the systemic circuit |
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smaller receiving chambers right receives deoxygenated blood from body and left receives oxygenated blood from the lungs. |
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larger muscular pumping right pumps to the lungs left to the body |
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held in place by special muscles and tendons called: papillary muscles that are attached to chordea tendinae |
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Pulmonary semilunar valve- entrance to pulmonary artery Aortic semilunar valve- at entrance to aorta. |
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How is blood supplied and drained from the myocardium? |
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coronary arteries first branches off the aorta goes to capillaries in heart muscle - cardiac veins collects blood from capillaries in heart muscle -coronary sinus Collects venous blood from heart and empties into the right atrium |
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relaxation phase blood from veins fill the atria |
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contraction phase heart muscle contracts sending blood first from the atria to the ventricles and then from the ventricles to pulmonary arteries and aorta |
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volume pumped by each ventricle per minute |
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How do you find the cardiac output |
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Stroke volume- amount pumped per beat heart rate- number of beats per minute CO= stroke vol * HR ave sv 70mls per beat and hr 70 |
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Sinoatrial node(conduction system) |
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pacemaker at top of right atrium |
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Between atria and ventricles |
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also called bundle of his top of interventricular septum |
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Right and left, run down the septum |
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branches that travel through myocardium of ventricles |
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1. Sa node generates elect impulse 2. travels through muscle of atria 3. AV node is stimulated 4.Impulse travels through av bundle, bundle branches, and purkinje fibers 5. ventricles contract |
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Lubb dubb lubb when av valvels close dubb when semilunar valves close |
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any abnormal heart sounds |
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inflammation of the lining of the heart |
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inflammation of the heart muscle |
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inflammation of the pericardium |
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caused by attack of rhuematic fever in childhood mitral stenosis valve cusps do not open mitral regurgitation valve cusps do not close |
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involves the walls of the blood vessels that supply the muscle of the heart |
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thickening and hardening of arteries |
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lack of blood to are fed by blocked arteries |
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closure of coronary arteries due to clot |
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pain caused by lack of blood to heart muscle. |
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arteries-carry blood away from the heart veins- carry blood towards heart venules- small veins capillaries- smallest vessels connect aterioles and venules |
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artery wall inner layer- endothelium single layer of flat epithelial cells middle layer layer of smooth muscle and elastic connective tissue outer layer layer of supporting connective tissue |
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an abnormal opening between the left and right atria of the heart |
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ventricular septal defect |
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a common congenital heart defect; an abnormal opening in the septum dividing the ventricles allows blood to pass directly from the left to the right ventricle; large openings may cause congestive heart failure |
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a blood vessel in a fetus that bypasses pulmonary circulation by connecting the pulmonary artery directly to the ascending aorta; normally closes at birth |
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is an abnormality of the heart rhythm, resulting in a rapid and sometimes irregular heartbeat. |
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In matters of the heart (cardiology), fibrillation is incoordinate twitching of the heart muscle fibers. |
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extrasytole (PVC) pre-ventricular contraction |
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Ectopic heartbeats are small variations in an otherwise normal heartbeat that causes an irregular pulse. They may occur without an obvious cause and are usually harmless. |
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a noninvasive diagnostic procedure that uses ultrasound to study to structure and motions of the heart |
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How do artery walls and vein walls differ? |
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Artery walls are thicker because the have to accommodate for a beating heart. |
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a natural or surgical joining of parts or branches of tubular structures so as to make or become continuous |
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a ring of arteries at the base of the brain |
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is formed by the ulnar artery, and is usually completed by a branch from the a. volaris indicis radialis, but sometimes by the superficial volar or by a branch from the a. princeps pollicis of the radial artery. The arch passes across the palm, describing a curve, with its convexity downward. |
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are venous channels found between layers of dura mater in the brain.[1] They receive blood from internal and external veins of the brain, |
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is a collection of veins joined together to form a large vessel that collects blood from the myocardium of the heart. |
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within the human head, is a large collection of thin-walled veins creating a cavity bordered by the temporal bone of the skull and the sphenoid bone, lateral to the sella turcica. |
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What is the hepatic portal system? |
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is the system of veins comprising the hepatic portal vein and its tributaries. |
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What are the forces involved in capillary exchange with tissues? |
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Picks up oxygen and drops it off primarily uses diffusion secondarily uses blood pressure (out) Osmotic pressure is used to move fluid back into the vessel |
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inadequate output of blood from heart |
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swelling and loss of function in superficial veins, usually legs and rectum. |
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functions of lymphatic system |
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Drain tissue fluid and proteins returns excess fluid to blood |
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superficial set just below skin, near superficial veins Deep set usually larger and located near deep veins named for location within body (femoral lymphatic vessel) |
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drains upper right part of body and empties into right subclavian |
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drains in the left subclavian. |
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filter lymph CONTAIN T LYMPHOCYTES are phagocytic |
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filter tissue fluid rather than lymph |
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causes t lymphocytes mature secretes thymosin |
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filters blood destroys old rbcs |
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inflammation of lymphatic vessels |
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inflammation of lymph nodes that occurs during infection |
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disease of lymph nodes caused by infectious agent or cancer |
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chronic malignancy with enlarged lumph nodes |
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more common in older adults |
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What is nonspecific defense? |
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Defense mechanisms that are effective against any harmful agent that enters the body. skin mucous membranes Body secretions- tears, saliva, digestive juices. reflexes- coughing and sneezing phogocytosis- neutrophilis and macrophages Natural killer cells kills abnormal cells by destroying their membrane inflammation fever increses metabolism interferon produced by cell infected by a vireus |
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What is specific defenses? |
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defense mechanisms that act only on specific agent. B cells make immunoglobulin (when we get the flu) Inborn immunity types: species population individual
Acquired immunity (after birth) Antigen- causes the immune system to respond.
Antibodies produced in response to foreign antigen.
-T-cells They are cytotoxic cells and destroy foreign cells. Macrophages phagocytic white blood cells derived from monocytes |
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any kind of disease causing organism tissue preference portal of entry virulence -invasive power -production toxins (strep) |
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Give examples of naturally acquired immunity and artificially acquired immunity. |
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Natural contact with a specific disease organism passive passage of antibodies from a mother to fetus through mother's breast milk artifically acquired active- through vaccination or immunization Attenuated vaccine- a weakened version of the infectious organism is used.
recombinate DNA vaccine genese for a disease antigen are inserted into a harmless organism. booster shots- repeated inoculations are given to maintain high level of antibodies. |
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What is phagocytosis and what cells are active in phagocytosis? |
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* process in which phagocytes engulf and digest microorganisms and cellular debris; an important defense against infection |
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abnormal reactivity to ones own tissues MS, juvenile diabities |
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immune deficiency disease |
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failure of some part of the immune systems AIDS kills the t cells especially the helpers. |
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