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Bio 101 Lecture 3: Cell Structure
Yahhh! First set :]
35
Biology
Undergraduate 2
10/06/2012

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Term
Cell Theory
Definition
-Cells are the basic units of organization and live in all living organisms
-All cells come from pre-existing cells
-All living cells evolved from common ancestor
Term
Biological Membrane
Definition
Consists of the lipid bilayer embedded with protein
Term
Lipid Bilayer
Definition
-Forms from phospholips with water (due to phosphate head is hydrophilic and fatty acid tail is hydrophobic)
-Pass through: hydrophobic molecules, water. Not: ions
Term
Light microscope (LMX
Definition
-Magnification: 1500-2000x
-Resolution: 0.2 um
-Dead or alive cells
-Orcein (protein) stains
Term
Electron Microscope (EM)
Definition
-Magnification: 1,000,000c
-Resolution- 1um - 0.2um
-Dead cells only
-Sections/Surface cell
Term
Biochemical Technique to Study Cells
Definition
-Centrifuge: puts certain parts into pellets after time durations (nuclei, mitochondria, in small pellet : ER, Golgi, plasma membrane)
Term
Prokaryotic Cell (example, size, characteristics, compnonents)
Definition
-Examples: Domain Bacteria and Archaea
-Size: 1-10um
-Lacks nucleus and membrane-bound organelles
-Cell wall: made of peptidoglycan (polymer of sugars and amino acids)
Term
Eukaryotic Cells (example, size, characteristics, compnonents)
Definition
-Example: Domain Eukarya
-Size range: 10 - 100 um
-Contains Nucleus and other membrane-bound organelles
Term
Endomembrane System
Definition
System network of organelles involved in manufacturing/transporting materials/proteins
-nucleus, endoplasmic reticulum (ER), Golgi complex, lysosomes, vesicles,
and vacuoles.
Term
Nucleus
Definition
-Most prominent organelle, "cell brain"
-Surrounded by nuclear envelope with nuclear pores in it
-Has a nucleolus: site of ribose assembly
-Has chromatin/chromosomes
Term
Nuclear Envelope/Pores Characterisits
Definition
Nuclear envelope is double membrane
-Pores regulate the passage of materials between nucleoplasm and cytoplasm
Term
DNA
Definition
-Inside the nucleus
-Duplicates through Replication
-Organized into units called genes
Term
Chromatin
Definition
-DNA+histone proteins
-Condenses into chromosomes
Term
Endoplasmic Reticulum
Definition
-Composed of membranes and lumen
-manufactures, processes, and transports a wide variety of biochemical compounds for use inside and outside of the cell.
Term
Smooth ER
Definition
-Synthesizes lipids and carbohydrates.
-In liver, enzymes help detoxify it
-An example: breaks down alcohol
Term
Rough ER
Definition
-Membrane is bound with ribosomes
-Synthesis and manufacture proteins
-In pancreatic cells to help pancreas function/digest
Term
Cytoplasm
Definition
Aquatic environment within a cell.
Term
Plasma Membrane
Definition
aka Cell membrane: biological membrane that separates the interior of all cells from the outside environment
Term
Ribosomes
Definition
Composed of rRNA (ribosomal RNA) + proteins
-Synthesized in the nucleolus
-Two types: free in the cytoplasm and membrane-bound ribosomes
-Fuction: protein synthesis
Term
Golgi Apparatus
Definition
-Components: membrane sacs called cisternae (cis face, trans face, media region).
-Receives materials from transport vesicles which bring molecules from the ER.
-Function: protein sorter and modification
Term
Lysosomes
Definition
-Small vesicles with digestive enzymes
-Two kinds: primary and secondary lysosomes
-Function rid of waste materials
Term
Primary + Secondary Lysosomes
Definition
-Bud from golgi apparatus
-Synthesized in rough ER
-They swallow outside material to turn into secondary lysosomes
Term
Examples of Lysosome malfunctions
Definition
Rheumatid Arthritis: Leaky Lysosomes
Tay-Sachs disease: mutation, hydrolytic enzyme is not functional
Term
Peroxisomes
Definition
-Vesicles holding digestive enzymes
-Absorb nutrients and digest fatty acids and alcohol
Term
Glyoxisomes
Definition
Specialized peroxisomes in oily seeds (e.g. peanuts)
Term
Vacuoles
Definition
-Water filled storage spaces in cells
-store food, collect waste products, and can help with cell shape and buoyancy
Term
Plant Vacuoles
Definition
-Surrounded by membrane called tonoplast
-90% of cell volume
-When they grow, turgor pressure: push plasma membrane against cell wall
Term
Cell Wall
Definition

-In plant cells only: acts as pressure vessel/prevents overexpansion when cells fillw ith water

Consists of: -Primary cell wall: cellulose -Secondary cell wall: lignin -In the middle lamella in primary cell wall: pectin (helps bind cells together)

Term
Mitochondria
Definition
Functions: aerobic respiration: converts energy into ATP (oxygen needed) and lets out waste
-Membrane bound and in most eukaryotic cells
-Not part of endomembrane system
Term
Chloroplasts
Definition

-Only found in plant cells/not part of endomembrane system

-Helps process of photosynthesis by storing/capturing sunlight to produce glucose (food for the plant)

Term
Cytoskeleton
Definition
-Protein fibers that protect against wear and tear
-Microfilaments (muscle contractions), microtubules(determine cell shapes and form the spindle fibers which separate chromosomes during mitosis) and intermediate filaments (more strength)
Term
Cilia + Flagella
Definition
-Whip-like appendages only on surface of eukaryotic cells and animal cells
-Function: move liquids past surface of the cells
Term
Cilia and Flagella Differences
Definition
Cilia is hair-like, short and many
Flagella more whip-like and few.
Term
Extracellular Matrix (ECM)
Definition
Network of non-living tissue that supports cell
-Have fibronectins (glycoproteins of the ECM) that bind to integrin and other receptors in the plasma membrane
Term
Messenger RNA (mRNA)
Definition
It transfers and carries genetic material from the DNA (in the nucleus) to the ribosome/cytoplasm for the manufacture of protein.
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