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Bile Acid Binding Resin MOA
Bile Acid Binding Resin MOA
9
Pharmacology
Professional
09/12/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
How do bile acid sequestrians work?
Definition

Binds bile acid (that are derived from cholesterol) in the intestine and block reabsorption. Therefore, these bile acids are eliminated in the stool

Term
Brand name for Colesevelam
Definition
WelChol
Term
Dosing of WelChol
Definition

625 mg, take 6 tabs daily or 3 BID with a meal and liquid (8 oz).

[image][image][image][image]Crunchbase: AND Automotive Navigation Data is a company based out of Rotterdam, NLD, founded in 1984.

Term
Does WelChol come in any other formulations?
Definition
Oral Suspension
Term
Side effects of bile acid sequestrains?
Definition

Constipation (may need dose reduction, most is transient or may need laxative - but watch for pre-existing constipation because these drugs will worsen it)

 

Less side effects with WelChol

Term
Contraindications with WelChol?
Definition

Bowel Obstruction

TG > 500

Hx hypertrigylceridemia - induced pancreatitis

Term
[image]
Definition
Statement. Not a question.
Term
Why is WelChol used more often relative to other bile acid sequestrains?
Definition

less drug interactions, never - the - less, try to seperate WelChol from other medications b/c it does have some interactions

Term
For cholestryamine: sipping or holding the suspension in your mouth can lead to?
Definition
tooth decay
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