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Big Enchilada
Exam 1
91
Pharmacology
Graduate
12/12/2011
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Term
Acetazolamide (Diamox)
 Definition
Carbonic Anhydrase inhibitor
Term
Mannitol (Osmitrol)
 Definition
Osmotic Diuretic
Term
Furosemide (Lasix)
 Definition
Loop Diuretic
Term
Ethacrynic Acid (Edecrin)
 Definition
Loop Diuretic
Term
Chlorthalidone (Hygroton)
 Definition
Thiazide
Term
Indapamide (Lozol)
 Definition
Thiazide
Term
Triamterene (Dyrenium)
 Definition
K-sparing Na channel inhibitor
Term
Amiloride (Midamor)
 Definition
K-sparing Na channel inhibitor
Term
Spironolactone (Aldactone)
 Definition
K-sparing aldosterone antagonist
Term
Eplerenone (Inspra)
 Definition
K-sparing aldosterone antagonist
Term
Drospirenone
 Definition
K-sparing aldosterone antagonist
Term
Desmopressin acetate
 Definition
Anti-diuretic
Term
Ca retention
 Definition
  • Acetazolamide
  • Thiazides
Term
Ca Loss
 Definition
  • Furosemide
  • Mannitol
Term
K-sparing Diuretics
 Definition
  • Triamterene
  • Amiloride
  • Spironolactone
Term
K-Wasteing diuretics
 Definition
  • Acetazolamide
  • Mannitol
  • Loops
  • Thiazides
Term
Sulfonamide deravitives
 Definition
  • Acetazolamide
  • Loops (not ethacrynic acid)
  • Thiazides
Term
A patient is allergic to sulfa drugs, but needs a diuretic, what can be given
 Definition
  • Mannitol (IV)
  • Ethacrynic acid (PO)
  • K-Sparing
Term
Treat Nephrolithiasis
 Definition
  • Loops
  • Thiazides
Term
Cause Nephrolithiasis
 Definition
  • Acetazolamide
  • Triamterene
Term
Cause acidosis
 Definition
  • Acetazolamide
Term
Cause Alkalosis
 Definition
  • Loops
  • Thiazides
Term
Causes pulmonary edema
 Definition
Mannitol
Term
Causes gout
 Definition
  • Loops
  • Thiazides
  • Niacin
Term
Causes hyperglycemia
 Definition
  • Loops
  • Thiazides
Term

Raises Cholesterol

 Definition
  • Lopps
  • Thiazides (not indapamide)
Term
Treat pulmonary edema
 Definition
  • Loops*
  • Thiazides
Term
Treat glaucoma
 Definition
  • Acetazolamide
  • Mannitol
Term
Treat Diabetes Insipidis
 Definition

Central: Desmopressin

Peripheral: Thiazides
Term
Methyldopa
 Definition

Adrenergic Neuron Blocker

(A2 agonist)
Term
Clonidine
 Definition

Adrenergic Neuron Blocker

(A2 agonist)
Term
Reserpine
 Definition
Adrenergic Neuron Blocker
Term
Prazosin
 Definition
α1 Adrenergic Receptor Blocker
Term
Doxazosin
 Definition
α1 Adrenergic Receptor Blocker
Term
Terazosin
 Definition
α1 Adrenergic Receptor Blocker
Term
Labetalol
 Definition
α1/β Blocker
Term
Nebivolol
 Definition

α1/β Blocker

and NO-releasing β1 blocker
Term
Hydralazine
 Definition
Direct Arteriolar Dilator
Term
Minoxidil
 Definition
Direct Arteriolar Dilator
Term
Verapamil
 Definition

Calcium Channel Blocker

(Heart)
Term
Diltiazem
 Definition

Calcium Channel Blocker

(Heart)
Term
Nifedipine
 Definition
Calcium Channel Blocker
Term
Felodopine
 Definition
Calcium Channel Blocker
Term
Amlodipine
 Definition
Calcium Channel Blocker
Term
Captopril
 Definition
ACE Inhibitor
Term
Enalapril
 Definition
ACE Inhibitor
Term
Lisinopril
 Definition
ACE Inhibitor
Term
Fosinopril
 Definition
ACE Inhibitor
Term
Quinapril
 Definition
ACE Inhibitor
Term
Ramipril
 Definition
ACE Inhibitor
Term
Losartan
 Definition
Angiotensin II Receptor Blocker
Term
Valsartan
 Definition
Angiotensin II Receptor Blocker
Term
Candesartan
 Definition
Angiotensin II Receptor Blocker
Term
Aliskiren
 Definition
Renin inhibitor
Term
Atenolol
 Definition
Selective β-blocker
Term
Acebutalol
 Definition
Selective β-blocker
Term
Metoprolol
 Definition
Selective β-blocker
Term
Nadolol
 Definition
Non-Selective β-blocker
Term
Propranalol
 Definition
Non-Selective β-blocker
Term
Pindolol
 Definition

Non-Selective β-blocker

with ISA
Term
Timolol
 Definition
Non-Selective β-blocker
Term
Safe for pregnancy
 Definition
  • Diuretics
  • Methyldopa
  • Beta blockers
  • CCB
Term
Postural hypertension
 Definition
  • Neuronal inhibitors
  • α1 blockers
  • Nitrates
Term

↓ triglycerides

↑ HDL

 

 Definition

α1 antagonists

 
Term

↑ Triglycerides

↓HDL

 Definition
β blockers
Term

Mask sign of hypoglycemia

focus on sweating

 Definition
β blockers
Term
Autoimmune side effects
 Definition
Methyldopa
Term
Ezetimibe (Zetia)
 Definition
Cholesterol absorption inhibitor
Term
Cholestyramine (Questran)
 Definition
Bile Acid Binding Resin
Term
Colestipol (Colestid)
 Definition
Bile Acid Binding Resin
Term
Colesevelam (Welchol)
 Definition
Bile Acid Binding Resin
Term
Lovastatin
 Definition
HMG-COA Reductase Inhibitor
Term
Pravastatin
 Definition
HMG-COA Reductase Inhibitor
Term
Simvastatin
 Definition
HMG-COA Reductase Inhibitor
Term
Atorvastatin
 Definition
HMG-COA Reductase Inhibitor
Term
Rosuvastatin (Crestor)
 Definition
HMG-COA Reductase Inhibitor
Term
Gemfibrozil (Lopid)
 Definition
Fibric Acid Analogue (Fibrates)
Term
Fenofibrate (Tricor)
 Definition
Fibric Acid Analogue (Fibrates)
Term
Effect of ezetimibe
 Definition
↓LDL ↑HDL
Term
Effect of HMG-COA Reductase Inhibitors
 Definition

↓LDL ↑HDL

increases LDL receptors in liver: less circulating LDL
Term
Effect of Niacin on Cholesterol
 Definition
↓VLDL ↓LDL ↑HDL
Term
Effect of fibrates
 Definition
↓VLDL ↓LDL ↑HDL
Term
Effect of Lovaza
 Definition

↓VLDL (no change in LDL)

(safe when combo with statins)
Term
Effect of bile acid bindingresins
 Definition
↓LDL
Term
Decreased absorption of dietary & Biliary Cholesterol across brush border
 Definition
Ezetimibe
Term

Exchange Cl for Bile acid

can't be absorbed

 Definition
Bile acid binding resin
Term
Bloating & Constipation
 Definition
Bile acid resins
Term
Inhibit intracellular lipolysis
 Definition
Niacin
Term

Peptic ulcers

gastric acid secretion

 Definition
Niacin
Term

Lipoproten Lipase

PPAR

 Definition
Fibrate
Term

effa

oxidation

 Definition
omega 3
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