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BI 202 Chapter 13
Heart and Circulation
29
Biology
Undergraduate 1
03/29/2012

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Term
Functions of Circulatory System
Definition

Transportation of respiratory gases

Delivery of nutrients & hormones

Waste removal

Temperature regulation

Clotting

Immune Function

Term
Cardiovascular Systems help by...
Definition

Heart pumps blood through cardiovascular system using

arteries, arterioles, capillaries, venules, veins

Term
Lymphatic System helps by...
Definition

Picks up excess fluid that is filtered out of capillary beds & returns fluids to veins.

Lymph nodes are included in this process.

Term
Structure of the Heart
Definition

4 Chambers: RA, RV, LA, LV

Valves: Right AV, Left AV, Aortic semilunar valve, Pulmonary  semilunar valve

Term
Fibrous Skeleton
Definition

Seperates atria & ventricles by dense connective tissue

Forms rings that support heart valves

Term
Myocardial Unit
Definition
atrial cells attact to top & bottom of fibrous skeleton
Term
Blood Cycle
Definition
Pulmonary Vein -> Right Atrium ->Right AV valve-> Right Ventricle ->Pulmonary Semilunar Valve -> Pulmonary Arterie -> Lungs -> Pulmonary Vein -> Left Atria -> Left AV Valve -> Left Ventricle -> Aortic Semilunar Valve
Term
Chordae Tendineae
Definition

Connect to AV Valves

Prevent AV Valves from opening due to hight pressure developed by contraction

Term
Systole/Diastole
Definition

Contraction/Relaxation

both atria contract together, then both ventricles contract together

Term

End-Diastolic Volume

(EDV)

Definition
volume of blood in ventricles at end of diastole (when full of blood)
Term

End- Systolic Volume

(ESV)

Definition
amount of blood left in ventricles at end of systole (when blood ejected)
Term

Isovolumic Contraction

(systole)

Definition
When ventricles contract, av valves close. Ventricular pressure is too low to open semilunar valves. (all 4 valves are closed)
Term

Ventricular Ejection

(systole)

Definition
ventricular pressure exceeds aortic pressure and pushes semilunar valves open (closes AV valves)
Term

Isovolumetric Ventricular Relaxation/ Filling

(diastole)

Definition
Ventricles relax and ventricular pressure decreases. When ventricular pressure falls below atrial pressure, AV valves open and blood flows from atrium to ventricals
Term
Lubb
Definition
closing of av valves
Term
dubb
Definition
closing of semilunar and aortic
Term
Myocardial Cells
Definition

short and branched

interconnected by gap junctions

forming muscle mass of heart chamber

Term
Sinoatrial Node
Definition

functions as pacemaker

depolarizes spontaneously to threshold (pacemaker potential)

Term
Cardiac Excitiation caused by SA Node
Definition

1. SA node begins

2.Atrial excitation

3. Sends to the dome of the heart

4. Ventricular Excitation

Term

Pacemaker Potentials

SA Node

Definition
has slow spontaneous depolarization (no resting membrane potential)
Term
Action Potentials
Definition

1. Na+ goes in during pacemaker potential

2. Opening of Ca+ channels in plasma membrane, Ca+ goes in creating upstroke & contraction

3. Repolarization happens by opeing voltage-gated K+ channels.

4. Repeat

Term

Myocardial Action Potentials

(plateau phase)

Definition
  • Myocardial Cells have a RPM of -90 mV
  • Depolarization to threshold comes from SA node
  • Upstroke occurs as Na+ channels open
  • MP declinds to -15 mv (plateau phase)
  • Plateau results from Ca2+ & K+
  • Repolarization is opening of extra K+ channels
Term
Conducting APs through Tissues of Heart
Definition
  • AP spreads thru myocardium causing atriums to contract
  • When it gets to AV node, AP travels down the AV bundle
  • The Bundle of HIS goes thru skeletons
  • Gives a rise to Purkinje Fibers near the apex of the heart.
  • Once it hits Purkinje Fibers, AP travels thru gap junctions causing ventricles to contract
  • Heart squeezes the heart from the bottom and blood is pushed thru semilunar valves.
Term
Excitation-Contraction Coupling
Definition

 

  • depolarization causes voltage gated Ca2+ to open in the sarcolemma
  • Releases Ca2+ in SR
  • Ca2+ binds to troponin and stimulates contraction (like skeletal muscle)
  • During repolarization Ca2+ is pumped out of cell and back into SR
Term
Refactory Period
Definition

Myocardial AP has long refractory period.

Heart can not be stimulated to contract again until it has relaxed

Term

Electrocardiogram

ECG

atrial/ventrical contract

Definition

P-Q-R ------Atrial Contract (lubb)

R-S-T-----Ventricles Contract (dubb)

Term
Structure of Blood Vessels
Definition

3 layers

  • tunica externia-connective tissue
  • tunica media- mostly smooth muscle
  • tunica internia- endothelium, basement membrane, & elastin
Term
 Capillaries are made up of only...
Definition
endothelial cells
Term
Skeletal Muscle Pumps
Definition
blood is moved to hear by sorrounding skeletal muscles (pumps)
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