Term
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Definition
Tamoxifen
trt of brst cancer estrogen blocker
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Term
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Definition
Anastrozole
trt of brst cancer, 1st line trt postmenapasal
selective non-steroidal aromatase inhibitor = dec estrogen
postmenapausal like SE
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Term
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Definition
Spironolactone
diuretic K sparing, trt of hypokalemia, trt of hyperaldosteronism untreatable w surgery
moa blocks aldosterone at N/k pumps
adv hyperkalemia, WEAKNESS, PARESTHESIA, MENTAL CONFUSION, DRY MOUTH, MUSCLE CRAMPS, hirsutism, gynecomastia, impotence, amenorrhea, |
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Term
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Definition
triamterene w/ hydrochlororthiazide
diuretic,
moa triamterene inhib reabsorbtion of Na triamterene is K sparing,
do not take w/ other K sparing diuretics
adv MUSCLE CRAMPS, WEAKNESS, RASH, dry mouth, orthostatic hypotension, |
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Term
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Definition
Metolazone
diuretic
used for edema, HTN
ADV MUSCLE CRAMPS, WEAKNESS, gout |
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Term
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Definition
Furosemide
diuretic K wasting
ADV HEARING LOSS, WEAKNESS, MUSCLE CRAMPS, ANEMIA,
contraindicated w sulfa allergy, gout, hypokalemia |
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Term
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Definition
HCTZ
diuretic
contraindicated in sulfa allergy
adv MUSCLE CRAMPS, WEAKNESS, anemia, orthostatic hypotension, transient blurred vision with all diuretics
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Term
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Definition
Bumetanide
Diuretic, K wasting
auditory toxicity inc w/ aminoglycosides and cisplatin
ADV MUSCLE CRAMPS, WEAKNESS, IMPAIRED HEARING, HYPOKALEMIA, azotemia
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Term
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Definition
Torsemide
diuretic,
contraindicated in sulfa allergy |
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Term
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Definition
Quetiapine
antipsychotic
contra-pts w demetiarelated psychosis,
ADV sedation, somnolence, dizzy, constipation, postural hypotension, dry mouth, dyspepsia |
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Term
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Definition
Ziprasidone
Antipsychotic
contra-in pts with demetia related psychosis, QT prolongation, MI,
ADV NMS (neurleptic malg syndrome) EPS, |
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Term
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Definition
Risperidone
antipsychotic
contr-in pt w dementia
ADV hyperprolactinemia, priapism, EPS, TACHYCARDIA, RASH, |
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Term
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Definition
Olanzapine
contra-in pts with dementia
ADV weight gain, TD, |
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Term
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Definition
Aripiprazole
antipsychotic
contr-pts w dementia
ADV NMS, TD, |
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Term
lithonate, Lithotabs, Lithobid |
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Definition
Lithium
DDI use w carbamazepine may cause neurotoxicity
NSAIDs, ACEI, & HCTZ = inc []
toxicity s/s DIARRHEA, VOMITING, DROWSINESS, BLURRED VISION, TINNITUS AND LOTS OF PEE
narrow therapeutic index drug, monitor lithium dec Na reabsorption which may lead to Na depletion and lithium toxicity, adequate Na and water intake needed |
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Term
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Definition
benztropine
antiparkinsons
moa blocks hist recpt in parasymp nervous syst
anticholinergic like affects
ADV dry mouth, blurred vision, constip, N, paralytic ileus w phenothiazines, dont use w BPH = no pee |
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Term
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Definition
carbidopa w/ Levodopa
antiparkinsons levoddopa =inc DA in brain carbidopa = decreased SE and more DA in brain by inhibiting enzyme that makes more DA outside of brain
DDI MAOI = hypertensive crisis
contr-w narrow angle glaucoma, melanomas, MAOI w/in 14 D.
ADV DYSTONIC or involuntaary movements |
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Term
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Definition
Pramipexole
antiparkinsons/ RLS
dopamine rec agonist
ADV hallucinations, orthost hypo, dizzy, dyskinesia, |
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Term
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Definition
ropinirole
antiparkinsons
dopaine agonist
ADV inhibits lactation, caution operating vehicls as pt may suddenly fall asleep, |
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