Lanoxin, Lanoxicaps, Digitek

Digoxin

for afib, an inotropic agent

gives inc in the force and velocity of systolic contractions, dec Hr, and dec conduction in AV node

diuretics may cause arrhythmias,

DDI's inc levels from:  erythromycin, propafenone, quinidine, amiodarone

Aggrenox

Dipyridamole and Aspirin

to dec risk of stroke

dec platelet aggregation

Coumadin, Jantoven

warfarin

factors 2,7,9,10 K-dependent

preg category X

Nitrostat, Nitroquick

Nitroglycerin

for angina

Imdur

Isosorbide Mononitrate

for prophylactic trt of angina

moa dec o2 demand through relaxation of vascular sm (dec afterload, and inc blood flow in heart)

Reglan

Metoclopramide

for gastroparesis (take 30 min AC), N/V,

moa inhib of DA receptors (antiemetic effects)

inc GI motility, has risk of tardive dyskinesia

Zofran

Ondansetron

for: N/V,

5ht3 rec blocker

no sig DDI's

Phenergan

Promethazine

for:  allergic rhinitis, motion sickness, NV, sedation

H1 rec blocker (antihist)

Compazine

Prochlorperazine

for psychosis, NV, anxiety

moa - blocks DA rec, takes 1hr to effect

Lomotil

Diphenoxylate with Atropine

for diarrhea

diphenoxylate binds opiod rec in GI = dec peristalsis

atropine antimuscrinic added mostly to dec abuse

may dec effectiveness of haloperidol and inc risk of TD

zyloprim

Allopurinol

for gout

trt and prevention

colchicine

gen only

for prophylaxis and pain of gout

inhibits migration of granulocytes into the inflammed area

may cause thrombocytopenia, anemia, agranulocytosis

common NV

Carafate

Sucralafate

trt of ulcer, covers ulcer site and protects from acid

may dec actions of many drugs -  give sucralafate 2hrs after meds

Cialis

Tadalafil

for ED  10mg prior to sex

cyp 3a4 inh (ketoconazle, ritonavir) inc []

tadalafil has no effect w/o sexual arousal 

see dr. if erection >4hr

Levitra

Vardenafil

for ED 1 hr prior to sex

also cyp3a4 met + cyp3a5 (inc [] w/ ketoconazole, ritonavir, erythromycin, grapefruit juice)

 no effect w/o stimulation

Viagra

Sildenafil

ED take 4hr-30min  prior to sex

no effect in absence of stimulation

cyp3a4 cleared (inc [] w/ ketoconazole, cimetidine, erythromycin)

do not use these ED meds inpts on nitrates or high CVD risk

boniva

Ibandronate

trt of OP (osteoporosis) in post menapausal women

bisphosphanate

Fosamax

Alendronate

osteoporosis

bisphosphonate

Actonel

Risedronate

osteoporosis

bisphosphonate

Evista

Raloxifene

osteoporosis

selective estrogen receptor modulator SERM, produces estrogen like effect

DVT risk dont use if pt immobile, preg X, dont use w hx of DVT,