-B1 selective

-low lipid sol (no CNS effect)

-12-14hr duration

-PO

-B1 selective

-PO

-active metabolite= acetylated

-some MSA

-#1 for HTN

-B1 selective

-IV

-anti-arrhythmic (despite lack MSA)

-B1 & B2

-PO

-24hr duration

-B1 &B2

-high lipid sol

>90% plasma binding (drug interaction)

-active metabolite = OH propanolol (P450)

-PO, IV

- high MSA (mouth numb)

-anti-arrhythmic

-B1 & B2

-#1 for chronic glaucoma treatment

-B1 & B2

-PO

-anti arrhythmic

-not used for HTN, angina, hyperthyroidism

labetalol

(carvedilol)

-B1, B2 & a1

-some lipid sol

-PO

-does NOT cause cold fingers