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Benign Skin Lesions
By Dr. Bardin
68
Medical
Professional
04/18/2012

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Term
Name some benign skin lesions of the pidermis?
Definition
seborrheic keratosis, dermatosis papulosa nigra, cysts
Term
T/F Seborrheic keratosis is a premalignant lesion.
Definition
false
Term
What percent of black adults have dermatosis papulosa nigra?
Definition
35%
Term
Dermatosis papulosa nigra is a variant of what type of benign skin lesion?
Definition
seborrheic keratoses
Term
Morgan Freeman's skin lesion=
Definition
dermatosis papulosa nigra
Term
What are the different types of cysts?
Definition
epidermal, pilar, digital mucous
Term
Where are epidermal and pilar cysts typically seen?
Definition
head, neck, and trunk in solitary or multiple lesions
Term
What do epidermal/pilar cysts look like?
Definition
round, slightly elevated nodulocystic lesions with a central puncta; may have associated discharge or become inflammed
Term
What are the differences between epidermal and pilar cysts?
Definition
epidermal= mostly on face and trunk, true epidermal lining with granular cell layer and contents are thick and cheesy
pilar= firm cysts almost exclusively on scalp, epidermal lining that lacks a granular cell layer, contents are oily and keratinous, may have calcifications, often dominant inherited
Term
What are milia?
Definition
tiny epidermal cysts that occur most commonly on the facial area
Term
What is a digital mucous cyst?
Definition
translucent cyst on a terminal digit; has no epidermal lining and may connect to the DIP joint
Term
Name some benign skin lesions of epidermal appendages?
Definition
sebaceous hyperplasia, trichoepithelioma, syringoma
Term
What is the appearance of sebaceous hyperplasia?
Definition
mutliple flat-topped papules with central umbilication that are yellow in color. Usually on the face of middle-aged adults
Term
What age group is affected by trichoepitheliomas most commonly?
Definition
young adults
Term
What is a trichoepithelioma?
Definition
tumor of hair follicle origin or differentiation
Term
How are trichoepitheliomas inherited?
Definition
dominantly
Term
What is a syringoma?
Definition
tumor of eccrine sweat duct
Term
In what patient population are syringomas most common?
Definition
asian women during puberty
Term
Where do syringomas occur?
Definition
face and eyelids
Term
What do syringomas look like?
Definition
semi-translucent papules
Term
From what structures do cutaneous leiomyomas arise from?
Definition
arrector pili muscles or venous musculature
Term
Patients with cutaneous leiomyoma complain of...
Definition
painful lesion
Term
What's the difference and similarities between nevus cells and melanocytes?
Definition
both originate from the neural crest and produce melanin pigment; melanocytes occur singularly and have dendrites; nevus cells occur in nests and have no dendrites
Term
Describe a junctional nevus.
Definition
flat and pigmented
Term
Describe a compound nevus.
Definition
raised and pigmented
Term
Describe a intradermal nevus.
Definition
raised and non-pigmented
Term
Is a nevocellular nevi a premalignant lesion?
Definition
no
Term
When should you biopsy a nevocellular nevi?
Definition
changes color/shape/size, bleeding or ulceration, development of satellite lesions
Term
What is the definition of a nevus?
Definition
nondendritic pigment cell; OR an increase or decrease in normal cellular constituents in a normal location
Term
What does a linear epidermal nevus look like?
Definition
verrucous, dirty-gray papules which coalesce in to a serpiginous plaque
Term
What determines where linear epidermal nevus occur?
Definition
they follow the lines of blaschko from embryological development
Term
What is the medical term for "liver spots"?
Definition
solar lentigo
Term
What are becker's nevus made up of?
Definition
epidermal melanocytes
Term
What cells make up solar lentigo?
Definition
epidermal melanocytes
Term
What cells make up cafe au lait spots?
Definition
epidermal melanocytes
Term
What is the medical term for freckle?
Definition
ephelides
Term
What causes freckles?
Definition
epidermal melanocytes
Term
What is Richard Gere's skin lesion?
Definition
Becker's nevus
Term
What is the tyndall effect?
Definition
the way light is scattered by dermal melanocytes to give the lesion a blue color
Term
Which lesions exhibit the tyndall effect?
Definition
blue nevus, mongolian spot, nevus of ota, nevus of ito
Term
A blue lesion on the eye due to a collection of dermal melanocytes is called a...
Definition
nevus of ota
Term
What is the medical term for port wine stain?
Definition
nevus flammeus
Term
What causes a nevus flammeus?
Definition
dilatation of capillaries
Term
What is the prognosis of nevus flammeus?
Definition
does NOT resolve, may become nodular over time
Term
What infantile or strawberry hemangioma?
Definition
a benign tumor of endothelial cells causing a proliferation of capillaries
Term
What is the prognosis of infantile hemangioma?
Definition
75-95% regress by 5-7 years of age
Term
What is a cavernous hemangioma? (appearance, prognosis, etc.)
Definition
a congenital lesion involving larger vessels and deeper structures that is usually blue in color and a compressible mass
Term
What are the components of sturge weber syndrome?
Definition
V1 port wine stain, seizures, glaucoma
Term
What are the features of Klippel Trenaunay syndrome?
Definition
limb hypertrophy + capillary, lymphatic or venous malformation
Term
What are the features of Kassabach Merritt?
Definition
consumptive coagulopathy + hemangioma
Term
What is Maffuci's syndrome?
Definition
dyschondroplasia (fragile bones) and enchondromas
Term
What is Blue rubber Bleb syndrome?
Definition
vascular proliferations of skin and GI tract with GI bleeding
Term
Name some acquired benign skin lesions of blood vessels.
Definition
cherry angioma and venous lake, nevus vasculosis ("spider hemangioma"), pyogenic granuloma
Term
What causes pyogenic granuloma?
Definition
trauma
Term
Whatis the medical term for "spider hemangioma"?
Definition
nevus vasculosis
Term
In what patient population are cherry angiomas/venous lakes most common?
Definition
adults
Term
What is the apperance of cherry angiomas? venous lakes?
Definition
cherry angiomas are multiple small red papules; venous lakes are soft blue papules
Term
What is a nevus vasculosis?
Definition
dilated arteriole connecting with a network of dilated superficial capillaries
Term
"cluster of grapes" or "frog spawn" is a common name for what condition?
Definition
lymphangioma; localized dilated lymph vessels
Term
Name some benign skin lesions made up of dermal connective tissue?
Definition
acrochordon, dermatofibroma, keloid
Term
What is another name for acrochordon?
Definition
fibroepithelial polyp (or skin tag)
Term
Describe fibroepithelial polyps?
Definition
small fleshy pedunculated papules in clusters in intertriginous areas
Term
What is the "dimpling sign"?
Definition
dimpling upon squeezing of a dermatofibroma
Term
What causes dermatofibromas?
Definition
usually secondary to trauma
Term
What ethnic groups are at highest risk for keloids?
Definition
african and mediterranean ancestry
Term
T/F Keloids can form spontaneously, i.e. without any previous trauma.
Definition
true
Term
What benign skin lesion exhibits the "button-hole" sign?
Definition
neurofibroma of von recklinghausen's disease
Term
What is another name for neurofibromatosis type I?
Definition
von recklinghausen's disease
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