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BE320 - Exam 1
Sherwood Ch. 13, 11, 10
247
Physiology
Undergraduate 3
12/04/2011

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Term
2,3-biophosphoglycerate (BPG)
Definition
erythrocyte constituent produced during red blood cell metabolism, can bind reversibly with Hb and reduce its affinity for O2
Term
B lymphocytes
Definition
produce antibodies and are responsible for antibody-mediated (humoral) immunity
Term
Bohr effect
Definition
influence of CO2 and acid on the release of O2, allosteric binding of them reduce affinity for oxygen
Term
Boyle's Law
Definition
at any constant temperature, the pressure exerted by a gas varies inversely with the volume of the gas
Term
Haldane effect
Definition
removing O2 from Hb increases the ability of Hb to pick up CO2 and CO2-generated H+
Term
Hering-Breuer reflex
Definition
triggered to prevent overinflation of the lungs when tidal volume is over 1L
Term
Korotkoff sounds
Definition
distinct from the heart sounds associated with valve closure heard when listening to the heart with a stethoscope
Term
O2-Hb dissociation curve
Definition
relationship between Hb and O2 association shown by an S-shaped graph
Term
T lymphocytes
Definition
do not produce antibodies, they directly destroy their target cells by releasing chemicals that punch holes in the victim cell (cell-mediated immunity)
Term
Type I alveolar cells
Definition
make up the alveolar walls; flattened
Term
Type II alveolar cells
Definition
secrete pulmonary surfactant
Term
accessory inspiratory muscles
Definition
in the neck, raise the sternum and elevates the first two ribs, enlarging the upper portion of the thoracic cavity
Term
active hyperemia
Definition
local O2 concentration decreases yielding local arteriolar dilation by relaxation of arteriolar smooth muscle
Term
albumin
Definition
most abundant plasma protein, nonspecifically bind many substances that are poorly soluble in plasma; plasma protein
Term
alpha globulins
Definition
used to highly specific bind poorly water-soluble substances for transport, factor involved in the blood-clotting process, inactive, circulating proteins; plasma protein
Term
alveolar dead space
Definition
any ventilated alveoli that do not participate in gas exchange with blood because they are inadequately perfused
Term
alveolar interdependence
Definition
neighboring alveoli, by recoiling in resistance to being stretched, exert expanding forces on collapsing alveolus and thereby keep it open
Term
alveolar surface tension
Definition
displayed by the thin liquid film that lines each alveolus
Term
alveolar ventilation
Definition
volume of air exchanged between the atmosphere and alveoli per minute [VA=(TV-DSV)*RR] (avg = 4200 mL/min)
Term
alveoli
Definition
termimals of the brochi and bronchioles; tiny air sacs where gases are exchanged
Term
anatomic dead space
Definition
air that doesn't get down to the site of gas exchange (avg = 150mL)
Term
anemia
Definition
below-normal O2-carrying capacity of blood and is characterized by low hematocrit
Term
anemic hypoxia
Definition
reduced O2 carying capacity of the blood
Term
angiogenesis
Definition
process of generating new vessel growth
Term
aortic arch barorecptors
Definition
involved in moment-to-moment regulation of blood pressure, mechanorecptor, sensitive to MAP and pulse pressure; located in major arterial trunk before it gives off branches
Term
aortic bodies
Definition
part of peripheral chemoreceptors found in the arch of the aorta
Term
aplastic anemia
Definition
caused by failure of the bone marrow to produce enough RBCs
Term
apneustic center
Definition
prevents the inspiratory neurons from being switched off
Term
apnnueusis
Definition
prolonged inspiratory gasps abruptly interrupted by very brief expirations
Term
arteries
Definition
carry blood from the heart to the organs, branch or diverge into a "tree" of progressively smaller vessels
Term
arterioles
Definition
branches of an artery at the organ level
Term
asthma
Definition
airway obstruction is due to thickening of airway walls, plugging of the airways by mucus, and airway hyperesponsiveness (profound constriction of smaller air pathways from spasm of smooth muscles)
Term
atmospheric (barometric) pressure
Definition
pressure exerted by the weight of the air in the atmosphere on objects on Earth's surface (760mmHg); diminishes with increasing altitude
Term
autoregulation
Definition
local arteriolar mechanisms that keep tissue blood flow fairly constant despite rather wide deviations in mean arterial driving pressure
Term
baroreceptor reflex
Definition
change in mean arterial pressure triggers autonomically mediated reaction that influences heart and blood vessels to adjust cardiac output and total peripheral resistance in an attempt to restore blood pressure to normal
Term
barorecptors
Definition
monitor mean arterial pressure within the circulatory system
Term
basophils
Definition
least numerous and similar structurally and functionally to mast cells
Term
beta globulins
Definition
used to highly specific poorly water-soluble substances for transport, factor involved in blood-clotting; plasma protein
Term
bicarbonate
Definition
HCO3-, primary form of CO2 transport in the blood
Term
bicarbonate (HCO3-)
Definition
60% of CO2 of blood is in this form
Term
blood coagulation (clotting)
Definition
transformation of blood from a liquid into a solid gel
Term
blood pressure
Definition
force exerted by the blood against a vessel wall, depends on the volume of blood contained within the vesseland the compliance of the vessel walls
Term
bone marrow
Definition
erythrocyte factory, soft highly cellular tissue that fills the internal cavities of bones
Term
breathing (ventilation)
Definition
air is alternately moved in and out of the lungs; mechanical act
Term
brochoconstriction
Definition
decrease in the radius of bronchioles
Term
bronchi
Definition
divisions of the trachea; left and right feed into the two lungs; branch out into smaller pathways
Term
bronchioles
Definition
smaller branches of the bronchi
Term
bronchodilation
Definition
increase in brochiolar radius
Term
bulk flow
Definition
various constituents of the fluid are moving together in bulk, or as a unit
Term
capillaries
Definition
smallest of the vessels, across which all exchanges are made with surrounding cells
Term
capillary blood pressure (Pc)
Definition
fluid or hydrostatic pressure exerted on the inside of the capillary walls by blood; tends to force fluid out of the capillaries into the interstitial fluid
Term
carbamino hemoglobin (HbCO2)
Definition
name used when CO2 is combined with Hb, binds to globin portion, does not compete with O2, carries 30% of CO2 in blood
Term
carbonic acid
Definition
H2CO3, first step of CO2 to HCO3-
Term
carbonic anhydrase
Definition
enzyme in red blood cells that converts CO2 to HCO3-
Term
carbonic anhydrase
Definition
enzyme in RBCs critical to transport CO2
Term
carboxyhemoglobin (HbCO)
Definition
name used when Hb is combined with CO, competes with O2
Term
cardiovascular control center
Definition
region in the medulla of brain stem that adjusts sympathetic output to the arterioles
Term
cardiovascular control center
Definition
integrating center that receives info on MAP, located in medulla within the brain stem, uses autonomic nervous system to alter balance of sym and parasympathetic activity to effector organs
Term
carotid bodies
Definition
part of peripheral chemorecptors located at the fork of the common carotid arteries on both right and left sides, more important peripheral bodies
Term
carotid sinus barorecptors
Definition
involved in moment-to-moment regulation of blood pressure, mechanorecptor, sensitive to MAP and pulse pressure; located near vessels leading to brain
Term
central chemoreceptors
Definition
located in the medulla near the respiratory cnet; sensitive to changes in CO2-induced H+ conc. in ECF of brain; increase CO2 --> stimulation of ventilation
Term
chloride (Cl-) shift
Definition
chrloride ions diffuse into the red blood cells down electrical gradient created by HCO3- exodus
Term
chronic bronchitis
Definition
long-term inflammatory condition of the lower respiratory airways, prolonged thickening of the airway linings, coupled with overproduction of thick mucus
Term
chronic obstructive pulmonary disease (COPD)
Definition
group of lung diseases characterized by increased airway resistance resulting from narrowing of the lumen of the lower airways
Term
circulatory hypoxia
Definition
too little oxygenated blood is delivered to the tissues
Term
clot retraction
Definition
contraction of the platelets trapped within the clot shrinks the fibrin mesh by exuding fluid
Term
clotting cascade
Definition
series of sequential reactions until thrombin catalyzes the final conversion of fibrinogen into fibrin
Term
collateral ventilation
Definition
airflow between adjacent alveoli through the pores of Kohn
Term
compliance
Definition
how much effort is required to stretch or distend the lungs
Term
compliance (disensibility)
Definition
how easily they can be stretched
Term
diaphragm
Definition
floor of thoracic cavity; large, dome-shaped sheet of skeletal muscle that completely separates the thoraciccavity from the abdominal cavity
Term
diastolic pressure
Definition
minimum pressure within the arteries when the blood is draining off into the rest of the vessels
Term
dorsal respiratory group
Definition
consists mostly of inspiratory neurons who innervate the inspiratory muscles which stimulate the muscles, important interconnections with the ventral group
Term
dyspnea
Definition
mental anguish associated with unsatiated desire for more adequate ventilation
Term
edema
Definition
swelling of the tissue because of excess interstitial fluid
Term
elastic recoil
Definition
how readily the lungs rebound after having been stretched
Term
emboli
Definition
free floating clot
Term
emphysema
Definition
collapse of the smaller airways and breakdown of alveolar walls, irreversible, results from excessive release of destructive enzymes
Term
endothelial cells
Definition
specialized epithelial cells that line the lumen of all blood vessels, release chemical mediators that play a key role in locally regulating arteriolar caliber
Term
endothelin
Definition
another endothelial vasoactive substance causes arteriolar smooth muscle contraction; one of the most potent vasoconstrictions
Term
eosinophils
Definition
increase in ciculating eosinophils (eosinophilia) is associated with allergic conditions and with internal parasite infestations
Term
erthyrocytes (red blood cells RBCs)
Definition
flat, disc-shaped cell indented in the middle on both sides
Term
erythropoeitin
Definition
hormone secrete by kidney into the blood, stimulates erythropoiesis
Term
erythropoiesis
Definition
process of generating new red blood cells
Term
expiration
Definition
one breath out
Term
expiratory muscles
Definition
muscles of the abdominal wall and internal intercostal muscles
Term
expiratory muscles
Definition
muscles of the abdominal wall and internal intercostal muscles
Term
expiratory reserve volume (ERV)
Definition
volume that can be actively expired (avg = 1000mL)
Term
external intercostal muscles
Definition
top most intercostal muscles, run downward and forward between adjacent ribs, enlarge the thoracic cavity in both the lateral and anterposterior dimensions (elevate the ribs)
Term
external respiration
Definition
exchange of O2 and CO2 between the external environment and the cells of the body
Term
extrinsic pathway
Definition
requires contact with tissue factors external to the blood, initiates clotting of blood that has escaped into the tissues
Term
factor X
Definition
converts prothrombin to thrombin, normally present in blood in an inactive form
Term
factor XIII (fibrin-stabilizing factor)
Definition
catalyze the cross-linkage process in clotting
Term
fibrin
Definition
an insoluble, threadlike molecule
Term
fibrinogen
Definition
large, soluble plasma protein produced by the liver and normally always present in the plasma
Term
fibrogen
Definition
key factor in blood clotting; plasma protein
Term
flow rate
Definition
blood through a vessel is directly proportional to the pressure gradient and inversely proportional to vascular resistance
Term
forced (active) expiration
Definition
muscles must contract to further reduce the volume of the thoracic cavity and lungs
Term
forced expiratory volume in one second (FEV1)
Definition
volume expired during the first second of expiration in a VC determination, usually about 80% of VC
Term
functional residual capacity (FRC)
Definition
volume of air in the lungs at the end of normal passive expiration (FRC=ERV+RV) (avg = 2200mL)
Term
gamma globulin
Definition
immunoglobulins crucial to the body's defense mechanism; plasma protein
Term
globin
Definition
protein made up of four highly folded polypeptide chains
Term
glycolytic enzymes
Definition
one of the few molecules in the RBCs necessary to generate energy
Term
granulocyte colony-stimulating factor
Definition
stimulates increased replication and release of granulocytes, especially nuetrophils
Term
heme groups
Definition
nonprotein group, binds to one polypeptide of globin; each iron binds reversibly with a molecule of O2
Term
hemoglobulin
Definition
molecule that binds oxygen to carry it in the blood
Term
hemolysis
Definition
rupture of RBCs
Term
hemolytic anemia
Definition
caused by rupture of too many ciculating erythrocytes
Term
hemophilia
Definition
common cause of excessive bleeding; caused by deficiency of one of the factors in the clotting cascade
Term
hemorrhagic anemia
Definition
caused by losing a lot of blood, either acute, such as a bleeding wound, or chronic such as excessive menstrual flow
Term
hemostasis
Definition
arrest of bleeding from a broken blood vessel, stopping a hemorrhage
Term
histotoxic hypoxia
Definition
cells cannot use the O2 available to them; cyanide poisoning
Term
hypernea
Definition
increased ventilation that matches an increased metabolic demand
Term
hyperpoxia
Definition
above-normal aterial PO2 causes oxygen toxicity which can lead to cell damage in the brain and retina
Term
hyperventilation
Definition
occurs when a person "overbreathes", rate of ventilation exceeds body's metabolic needs for CO2 removal
Term
hypocapnia
Definition
below-normal arterial PCO2 levels; brought about by hyperventilation
Term
hypoxia
Definition
insufficient O2 at cell level
Term
hypoxic hypoxia
Definition
low arterial blood PO2 accompanied by inadequate Hb saturation
Term
infectious mononucleosis
Definition
number of lyphocytes in the blood increase but also many of the lymphocytes are atypical in structure; caused by a virus; pronounced fatigue, mild sore throat, and low grade fever
Term
initial lymphatics
Definition
small, blind-ended lymph vessels; permeate almost every tissue of the body
Term
inspiration
Definition
one breath in
Term
inspiratory capacity (IC)
Definition
maximum volume air that can be inspired at end of a normal quiet expiration (IC=IRV+TV) (avg = 3500)
Term
inspiratory muscles
Definition
muscles that contract to accomplish an inspiration during quiet breathing; diaphragm and intercostal muscles
Term
inspiratory reserve volume (IRV)
Definition
volume that can be maximally inspired over and above the typical resting tidal volume (avg = 3000mL)
Term
intercostal muscls
Definition
lie between the ribs
Term
intercostal nerves
Definition
activate intercostal muscles
Term
internal (cellular) respiration
Definition
the intracellular metabolic processes carried out within mitochondria, which O2 and produce CO2 while derivingni energy from nutrient molecules
Term
internal intercostal muscles (role in expiration)
Definition
pulls the ribs downward and inward
Term
intersitial fluid hydrostatic pressure (Pif)
Definition
fluid pressure exerted on the outside of the capillary wall by interstitial fluid, forces fluid into the capillaries
Term
interstitial fluid-colloid osmotic pressure (PIif)
Definition
force that does not normally contribute significantly to bulk flow; promotes fluid out of the capillaries
Term
intra-alveolar (intrapulmonary) pressure
Definition
pressure within the alveoli
Term
intrapleural (intrathoracic) pressure
Definition
pressure within the pleural sac, pressure exerted outside the lungs within the thoracic cavity
(756mmHg)
Term
intrapleural fluid
Definition
lubricates the pleural surfaces as they slide past each other during respiratory movements
Term
intrapleural fluid's cohesiveness
Definition
due to water molecules in intrapleural fluid, helps hold the pleural surfaces together, facilitates movement of lungs against the interior surface of chest wall, stickiness expands lungs with the thoracic wall
Term
intrinsic pathway
Definition
precipitates clotting within damaged vessels as well as clotting blood samples in test tubes; sets off with factor XII (Hageman factor)
Term
larnyx
Definition
voice box, located at entrance of the trachea; anterior protrusions form the Adam's apple
Term
law of mass action
Definition
if conc. of one substance involved in a reversible reaction is increased, the reaction is drive toward the opposite side
Term
leukemia
Definition
cancerous condition that involves uncontrolled proliferation of WBCs; inadequate defense capabilities against foreign invasion (cell are abnormal or immature)
Term
local metabolic changes that influence arteriolar radius
Definition
decreased O2, increased CO2, increased acid, increased K+, increased osmolarity, adenosine release, prostaglandin release
Term
lungs
Definition
two, divided into several lobes, each supplied by a bronchus; tissue consists of series of highly branched airways, the alveoli, the pulmonary blood vessels, and large quantities of elastic connective tissue
Term
lymph
Definition
interstitial fluid that enters a lymphatic vessel
Term
lymph nodes
Definition
located en route within the lymphatic system, contain bacteria-killing phagocytes
Term
lymph vessels
Definition
initial lymphatics converging, eventually empty into venous systems near where blood enters the right atrium
Term
lymphatic system
Definition
reabsorbs the extra fluid filtered into the interstitial fluid, accessory route by which fluid can be returned from the interstitial fluid to the blood
Term
lymphocytes
Definition
provide immune defense against targets for which they are specifically programmed; live for about 100 to 300 days
Term
lymphoid tissues
Definition
lymph nodes and tonsils; contain lymphocytes that produce lymphocytes
Term
macrophages
Definition
mature and enlarge monocytes, life span of months to years unless destroyed
Term
mast cells
Definition
never circulate in the blood but instead are dispersed in connective tissue throughout the body
Term
mean arterial pressure
Definition
average pressure driving blood forward into the tissues throughout the cardiac cycle; MAP = diastolic + 1/3 pulse pressure
Term
medullary respiratory center
Definition
consists of two neuronal clusters (dorsal and ventral respiratory groups)
Term
megakaryocytes
Definition
sheddings of these extrodinary large, bone marrow-bound cells create platelets
Term
metarteriole
Definition
thoroughfare channel which runs between an arteriole and venule; option for capillaries to come from or drain to
Term
microcirculation
Definition
arterioles, capillaries, and venules; only visible on a microscope; all located within organ
Term
monocytes
Definition
become professional phagocytes, circulate for only a day or two before settling down in various tissues
Term
mononuclear agranulocytes
Definition
monocytes and lymphocytes; single, large, nonsegmented nucleus and few granules
Term
muscles of the abdominal wall (role in expiration)
Definition
increase the intra-abdominal pressure which exerts an upward force on the diaphragm
Term
nasal passages (nose)
Definition
air way of respiratory system beginning
Term
neutrophilia
Definition
circulating neutrophils
Term
neutrophils
Definition
phagocytic specialists; release a web of extracellular fibers that contain bacteria-killing chemicals
Term
newborn respiratory distress syndrome
Definition
not enough pulmonary surfactant produced to reduce aleveolar surface tension; poorly compliant lungs; alveolar collapse
Term
nitric oxide (NO)
Definition
causes local arteriolar vasodilation by inducing relaxation of arteriolar smooth muscle
Term
nutritional anemia
Definition
caused by dietary deficiency of a factor needed for erythrocytes
Term
oxyhemoglobin
Definition
name used when hemoglobin is combined with O2
Term
percent hemoglobin (%Hb) saturation
Definition
a measure of the extent to which the Hb present is combined with O2
Term
peripheral chemoreceptors
Definition
lie at the fork of the common carotid arteries and in arch of aorta; respond to specific changes in chemical content of the arterial blood
Term
pernicious anemia
Definition
inability to absorb enough ingested vitamin B12 from the digestive tract
Term
pharynx
Definition
throat, serves as a common passageway for both the respiratory and digestive systems
Term
phrenic nerve
Definition
innervates the diaphragm
Term
plasma proteins
Definition
dispersed as colloid, don't exit through narrow pores, establish osmotic gradient between blood and interstitial fluid, primary force preventing excessive loss of plasma from capillaries; maintain plasma volume
Term
plasma-colloid osmotic pressure (PIp)
Definition
force caused by colloidal dispersion of plasma proteins; encourages fluid movement into the capillaries
Term
plasmin
Definition
slowly dissolved by a fibrinolytic enzyme
Term
plasminogen
Definition
inactive precursor of plasmin
Term
platelet plug
Definition
platelets quickly adhere to the collagen at the site of defect
Term
platelets (thrombocytes)
Definition
cellular element present in blood, average 250 million in each cubic mm; small cell fragments
Term
pleural cavity
Definition
interior of the pleural sac
Term
pleural sac
Definition
separates each lung from the thoracic wall and other surrounding structures
Term
pleurisy
Definition
inflammation of the pleural sac, painful breathing because of "friction rub"
Term
pluripotent stem cells
Definition
undifferenciated cells in red marrow capable of forming rbcs, leukocytes, and platelets
Term
pneumotaxic center
Definition
sends impluses to the DRG that help "switch off" the inspiratory neurons; dominates over apneustic
Term
pneumothorax
Definition
abnormal condition of air enter the pleural cavity
Term
polycythemia
Definition
too many circulating RBCs and an elevated hematocrit
Term
polymorphonuclear granulocytes
Definition
neutrophils, eosinophils, and basophils; segmented nuclei, abundance of membrane-enclosed granules
Term
pores
Definition
narrow, water-filled gaps lie at the junctions between the cells in capillaries
Term
pores of Kohn
Definition
exist in the walls between adjacent alveoli to permit airflow between them
Term
pre-Botzinger complex
Definition
generate respiratory rhythm; located near the upper end of the medullary respiratory center
Term
precapillary sphincters
Definition
wisps of spiraling smooth muscle cells surrounding metarterioles
Term
pressure gradient
Definition
ifference in pressure that is created by separating a region of higher pressure from a region of lower
Term
pressure reservoir
Definition
provides the driving force for blood when the heart is relaxing
Term
primary polycythemia
Definition
caused by a tumorlike condition of the bone marrow in which erythropoiesis proceeds at an excessive, uncontrolled rate instead of being subject to the normal erythropoietin regulatory mechanism
Term
pulmonary (minute) ventilation
Definition
volume of air breathed in and out in one minute (avg = 6000 mL/min)
Term
pulmonary fibrosis
Definition
scar-forming fibrous connective tissue as a result of chronically breathing in asbestos fiber or similar irritants
Term
pulmonary stretch receptors
Definition
activated by stretching of lungs at large tidal volumes; APs travel from these to inhibit inspiratory neurons
Term
pulmonary surfactant
Definition
complex mixture of lipids and proteins secreted by the Type II alveolar cells; lowers alveolar surface tension
Term
pulse pressure
Definition
difference between systolic and diastolic pressures
Term
reabsorption
Definition
net inward movement of fluid from the interstitial fluid into the capillaries takes place through the pores
Term
reactive hyperemia
Definition
after occlusion is removed, resulting transiently much higher blood flow to the previously tissue
Term
red blood cell count
Definition
5 million cells per cubic millimeter
Term
red bone marrow
Definition
capable of blood cell production, typical of children
Term
reduced hemoglobin (deoxyhemoglobin)
Definition
name used when hemoglobin is not bound with O2
Term
renal anemia
Definition
may result from kidney disease; inadequate erythropoietin secretion by diseased kidneys leads to insufficient RBC production
Term
residual volume
Definition
minimum volume of air remaining in the lungs even after maximal expiration (avg = 1200mL)
Term
resistance
Definition
measure of hindrance or opposition to the blood flow through a vessel
Term
respiratory airways
Definition
tubes that carry air between the atmosphere and air sacs; nasal passages, pharynx, trachea, larynx, bronchi
Term
respiratory quotient
Definition
ratio of CO2 produce to O2 consumed
Term
respiratory rate
Definition
breaths per min (avg = 12)
Term
respiratory system
Definition
respiratory airways, lungs, structures of the thorax involved in producing movement of air
Term
reticulocytes
Definition
immature erthythrocytes
Term
ribs
Definition
curved, 12 pairs, join at sternum; provide bony protection for lungs and heart
Term
secondary polycythemia
Definition
appropriate erythropoietin-induced adaptive mechanism to improve the bloods O2-carrying capacity in response to a prolonged reduction in O2 delivery to the tissues
Term
septicemic shock
Definition
widespread clotting occasionally triggered by release of tissue thromboplastin into the blood from large amounts of traumatized tissue
Term
serum
Definition
plasma minus fibrinogen and other clotting precursors that have been removed during the clotting process
Term
shear stress
Definition
blood flowing over the surface of the vessel lining creates a longitudinal force on the endothelial cells
Term
sickle cell disease
Definition
best-known example among various hereditary abnormalities of erythrocytes that make these cells very fragile
Term
sphygmomanometer
Definition
externally applied inflatable attached to a pressure guage
Term
spirogram
Definition
recording of rise and fall of air-filled drum in a spirometer which indicates volume changes
Term
spirometer
Definition
consists of an air-filled drum floating in a water-filled chamber
Term
spleen
Definition
limited ability to store healthy erthyrocytes, serves as resevoir site for platelets, and contains abundance of lymphocytes
Term
sternum
Definition
joining point of ribs in the front (anteriorly)
Term
sudden infant death syndrome (SIDS)
Definition
sleep apnea in infants, evidence suggests baby "forgets to breath"; respiratory control factors are immature, poorly developed carotid bodies
Term
systolic pressure
Definition
maximum pressure exerted in the arteries when blood is ejected into them
Term
thoracic (chest) cavity
Definition
consists of lungs, heart and associated vessels, esophagus, thymus, and some nerves
Term
thoracic vertebrae
Definition
joining point of ribs in the back (posteriorly)
Term
thorax
Definition
outer chest wall; formed by 12 pairs of ribs,sternum, and thoracic vertebrae
Term
thrombin
Definition
catalyzes conversion from fibrinogen to fibrin at the site of injury
Term
thrombocytopenia purpura
Definition
platelet deficiency indicator with visible as small, purplish blotches
Term
thrombopoietin
Definition
produced by liver, increases the number of megakaryocytes in the bone marrow and stimulates each to make more platelets
Term
thrombus
Definition
abnormal intravascular clot attached to a vessel
Term
tidal volume (TV)
Definition
air entering or leaving lungs during a singal breath (avg = 500 mL)
Term
tissue plasminogen activator (tPA)
Definition
activates plasmin to dispose of fibrin
Term
tissue thromboplastin
Definition
released by traumatized tissue and directly activates factor X
Term
total lung capacity (TLC)
Definition
maximum volume of air that lungs can hold (TLC=VC+RV) (avg = 5700)
Term
total peripheral resistance
Definition
total resistance offered by all the systemic peripheral vessels together
Term
trachea (windpipe)
Definition
conducts air from pharynx to the lungs
Term
transmural pressure gradient
Definition
atomopheric > intrapleural, greater pressure pusihgin outward than inward across lunch wall, pushes out on lungs expanding them, fill thoracic cavity
Term
ultrafiltration
Definition
pressure inside the capillary exceeds pressure outside, fluid is pushed out through the pores
Term
vascular spasm
Definition
reaction when a blood vessel is cut or torn, slows blood flow through the defect and thus minimizes blood loss
Term
vascular tone
Definition
state of partial constriction which establishes a baseline of arteriolar resistance
Term
vasoconstriction
Definition
narrowing of a vessel
Term
vasodilation
Definition
enlargement in the circumference and radius of a vessel as a result of its smooth muscle layer relaxing; decreased resistance and increased flow through that vessel
Term
veins
Definition
formed when venules rejoin
Term
ventral respiratory group
Definition
composed of inspiratory and expiratory neurons; inactive during quiet breathing; overdrive mechanism, important for active expiration; excited by dorsal group when high demand
Term
venules
Definition
formed when capillaries rejoin
Term
viscosity
Definition
friction developed between the molecules of a fluid as they slide over each other during flow of the fluid
Term
vital capacity (VC)
Definition
maximum volume of air that can be moved during a single breath following maximal inspiration (VC=IRV+TV+ERV) (avg = 4500mL)
Term
vocal folds
Definition
two bands of elastic tissue that lie across the opening of the larynx; vibration of --> voice
Term
white blood cell count
Definition
7000 per cubic millimeter
Term
yellow bone marrow
Definition
incapable of erythropoiesis, replaces red bone marrow with maturation
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