Term
| What is the risk of obtaining HIV by transfusion? |
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Definition
|
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Term
| In 1995, FDA recommended blood be screened for what AGN to detect HIV a week earlier? |
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Definition
|
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Term
True or False:
The risk of transfusing ABO incompatible blood is GREATER than the combined risks of ALL transfusions associated viral infections |
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Definition
|
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Term
| Which types of Hepatitis are the biggest threat when looking at blood transfusions? |
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Definition
|
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Term
| Viruses that persist where pose the greatest problems? |
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Definition
|
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Term
True or False:
There are only a few documented cases reported ever on viruses that persist in the blood |
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Definition
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Term
| ______ causes disease only when prior or concomitant infection with HBV |
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Definition
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Term
True or False:
There are NO reported cases of transfusion spread of HEV |
|
Definition
|
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Term
True or False:
HCV & HBV can be subclinical or overt with jaundice, fatigue, vomiting, and elevated liver enzymes |
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Definition
|
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Term
| Which is generally milder HBV or HCV? |
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Definition
|
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Term
| What can both HBV & HCV result in? |
|
Definition
Cirrhosis
Eventually Hepatocellular Carcinoma |
|
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Term
| ______ is the first serologic test to become positive 2-6 weeks after exposure to Hepatitis |
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Definition
|
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Term
| Before testing for HCV, you should use _____ ____ such as ALT |
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Definition
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Term
|
Definition
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Term
| Within a few year, over _____% of the hemophiliacs receiving clotting factor developed HIV |
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Definition
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Term
| HIV-__ is endemic in W. Africa, but rarely seen elsewhere |
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Definition
|
|
Term
True or False:
All blood components can transmit HIV-1 |
|
Definition
|
|
Term
| By the mid 1990s, over _____ cases of AIDS attributed to transfusion |
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Definition
|
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Term
| By the mid 1990s, _____ cases of AIDS attributed to hemophiliacs receiving clotting factors |
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Definition
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Term
| Now, the seronegative window for HIV is how many days? |
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Definition
|
|
Term
| What electrophoresis should you run to confirm HIV screening test? |
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Definition
|
|
Term
| "Look-Back" refers to what or whom? |
|
Definition
| ID of persons who received seronegative blood from a donor later found to be infected with HIV |
|
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Term
| ______ is associated with adult T-cell lymphoma |
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Definition
|
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Term
| Leukemia is what percentage of the people who have the HTLV-1 virus? |
|
Definition
|
|
Term
| Which Human T-cell Lymphotropic Virus is seen in Japan, sub-Saharan Africa, Caribbean, and Brazil? |
|
Definition
|
|
Term
| Which Human T-cell Lymphotropic Virus is seen in Nation Americans and IV drug users in the U.S.A.? |
|
Definition
|
|
Term
True or False:
BOTH HTLV-1 & HTLV-2 persist for life and are transmitted sexually or by parenteral exposure to blood |
|
Definition
|
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Term
| What type of Transfusion Transmitted Disease is common, usually benign, and the viral infection is seen in 50-70% of people? |
|
Definition
|
|
Term
| What illness is CMV like? |
|
Definition
|
|
Term
| CMV can be Very Serious in what type of patients? |
|
Definition
Premature infants
Immunosuppressed
-Especially Transplant Patients |
|
|
Term
| What type of patients MUST be protected from getting CMV? |
|
Definition
Low Birth Weight Infants
Inutero Transfusions
Seronegative bone marrow transplant patients |
|
|
Term
| What type of blood can you give to patients who must be protected from getting CMV? |
|
Definition
Seronegative blood
Leukodepleted RBCs |
|
|
Term
How often are the following passed through infected blood:
Epstein-Barr, parvovirus, Colorado Tick Fever |
|
Definition
|
|
Term
| What is the name of the Fatal disease caused by proteinaceous material called prion? |
|
Definition
| Creutzfeldt-Jakob Disease |
|
|
Term
| How often does Creutzfeldt-Jakob Disease occur in the U.S.A.? |
|
Definition
|
|
Term
| Fatal cases of Creutzfeldt-Jakob Disease have been transmitted through what? |
|
Definition
Growth hormone derived from human pituitary
Corneal transplants |
|
|
Term
True or False:
There has never been a reported case of Creutzfeldt-Jakob Disease from blood transfusions |
|
Definition
|
|
Term
| How many cases of West Nile Virus occurred from transfusions in 2002? |
|
Definition
|
|
Term
| What percent of transfusion fatalities are usually from donor venipuncture or unapparent baceremia? |
|
Definition
|
|
Term
| There is a ____% mortality rate in the recipient especially if the bacteria produce endotoxins |
|
Definition
|
|
Term
| What is the #1 cause of Transfusion Transmitted Diseases due to bacteria? |
|
Definition
|
|
Term
True or False:
There have been cases of autologous sepsis from bacteria growing during storage |
|
Definition
|
|
Term
True or False:
CMV is NOT a FDA required test for volunteer donors |
|
Definition
|
|
Term
| What is the most common parasitic infection from blood in the U.S.A? |
|
Definition
|
|
Term
| How common is Malaria from blood transfusion in the U.S.A? |
|
Definition
|
|
Term
| What is Babesia caused by? |
|
Definition
| Babesia microfti from infected deer tick |
|
|
Term
True or False:
Transfusion transmitted cases of Babesia are usually Very Mild but in Rare Cases can produce chills, headache, and hemolysis in immunocompromised patients |
|
Definition
|
|
Term
True or False:
There is NO Screening Test for Babesia |
|
Definition
|
|
Term
| Treponema pallidum cannot live for more than a few days at what temperature? |
|
Definition
|
|
Term
| Test for syphilis would not prevent because seroconversion occurs well after the phase of what? |
|
Definition
|
|
Term
| _____ is done to detect potentially high-risk behavior that makes transmission of organisms other than Treponema pallidum more likely |
|
Definition
|
|
Term
| What is the cause of Chagas? |
|
Definition
| Trypanosoma cruzi endemic in South & Central America |
|
|
Term
True or False:
There is no way atm to remove viruses from RBCs and Platelets in vitro |
|
Definition
|
|
Term
What are the following considered:
Pasteurization
Cold ehtanol precipitation
organic solvents & detergents |
|
Definition
| Ways to prevent infectious diseases |
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