Term
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Definition
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–HIV - Retrovirus
–Herpes Simplex Virus (HSV) - Herpesvirus
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Term
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Definition
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–Influenza - Orthomyxovirus
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Term
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Definition
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Hepatitis B (HBV)
Hepatitis C virus (HCV) |
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Term
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Definition
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–HIV - Retrovirus
–Epstein Barr Virus (EBV) - Herpesvirus
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Term
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Definition
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–Herpes Simplex Virus (HSV)-Herpesvirus
–Varicella Zoster (VZV)- Herpesvirus
–Rubella
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Term
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Definition
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–Herpes Simplex Virus (HSV) - Herpesvirus
–Human Papilloma virus (HPV)
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Term
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Definition
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•
–Cytomegalovirus (CMV)- Herpesvirus
–Herpes Simplex Virus (HSV) - Herpesvirus
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Term
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Definition
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•Binding to receptor
•Attachment and entry
•Uncoating
•Some RNA viruses are directly translated into protein some go through a RNA (negative strand) or DNA (retroviruses) intermediate
•DNA “provirus” enters nucleus is are transcribed into mRNA protein
•Genome replication
•Assembly
•Maturation
•Egress (and release)
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Term
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Definition
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refers to the ability of a pathogen to establish an infection
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Term
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Definition
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Localization of a virus or disease to specific cells or tissues, generally determined by cellular receptors
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Term
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Definition
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pathogens ability to evade and overwhelm the host defense mechanisms and cause disease
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Term
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Definition
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is the degree of pathogenicity of an organism: the relative ability of a pathogen to cause disease.
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Term
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Definition
viruses enter the bloodstream disseminate
within host: virus can be free or cell-associated |
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Term
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Definition
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the route by which an infectious agent enters the body
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Term
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Definition
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Concentration of viral particles per ml
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Term
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Definition
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The amount of virus in the blood, a measure of severity of infection
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Term
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Definition
Genome: RNA
Polarity: ss
Lipid Envelope: No
Examples/Diseases: Polio, HepatitisA, Colds |
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Term
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Definition
Genome: RNA
Polarity: ss
Lipid Envelope: Yes
Examples/Diseases: HIV/AIDS |
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Term
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Definition
Genome: RNA
Polarity: ss
Lipid Envelope:Yes
Examples/Diseases: Infuenza |
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Term
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Definition
Genome: DNA
Polarity: ds
Lipid Envelope:NO
Examples/Diseases:HPV/Warts |
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Term
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Definition
Genome: DNA
Polarity: ds
Lipid Envelope:Yes
Examples/Diseases: HVS, VZV, EBV, CMV/Mononucleosis, Cancer |
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Term
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Definition
Genome: RNA
Polarity: ss
Lipid Envelope:Yes
Examples/Diseases:Hapatitis C |
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Term
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Definition
Genome: DNA
Polarity: ds
Lipid Envelope:Yes
Examples/Diseases: Hepatitis B |
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Term
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Definition
Criteria:
Morphology:
DNA or RNA genome
single-stranded (ss) or double-stranded (ds) RNA or DNA
linear or circular, fragmented or nonfragmented
Lipid envelope or the lack of it
Mechanisms of gene expression and virus replication
positive- or negative-strand RNA |
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Term
| Viral Replication only in cytoplasm: |
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Definition
| most RNA viruses except retrovirus and Orthomyxovirus (Influenza |
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Term
| Viral Replication only in Nucleus |
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Definition
Most DNA viruses
ssRNA(-) virus Orthomyxovirus |
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Term
| Viral Replication in both compartments |
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Definition
ssRNA(+) using DNA intermediate retrovirus
dsDNA virus using an RNA intermediate Hepadnavirus |
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Term
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Definition
| Produced primarily by macrophages and lymphocytes in response to a pathogen or stimulation by other products of inflammation |
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Term
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Definition
-Produced and released by virally infected host cells
-Prevent further infection and spread
-Effective against wide range of viruses
-Type: I IFN-alpha and IFN-beta produced by macrophages
-Induced production of antiviral proteins by host cells
Type II: IFN-gama by T-lymphocytes
-Increases microbiocidal activity of macrophage |
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