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Basic Physiology
Homeostasis - Respiration
64
Biology
Undergraduate 2
02/07/2010

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Term
What do we need to digest food?
Definition
Body systems
Term
Why do we need body systems to digest food?
Definition
We need energy.
Term
What is homeostasis?
Definition
An internal condition maintained by internal responses that compensate for changes in the external environment.
Term
What kind of condition is homeostasis?
Definition
Dynamic.
Term
What kind of condition is homeostasis?
Definition
Dynamic.
Term
What kind of things are constantly being made to counteract environmental changes?
Definition
Internal adjustments (to restore balance -- stasis). Examples: Being cold, getting sick.
Term
What are internal responses?
Definition
Your body functions. They are the physiological processes of your body -- the physical and chemical parameters that an organism must maintain to allow proper functioning of its component cells, tissues, organs, and organ systems.
Term
Why do we need to achieve homeostasis?
Definition
Homestasis allows for maximum internal efficiency.
Term
What are some examples of homeostasis achieving maximum internal efficiency?
Definition
Enzymes function best in certain pH ranges; The balance between having too much and too little water in your cells.
Term
What kind of fluid are our cells surrounded by?
Definition
Interstitial (extracellular) fluid.
Term
What is in interstitial fluid?
Definition
Ions (involved in maintaining osmotic balance) and complex molecules (used as an energy source).
Term
What is interstitial fluid involved in?
Definition
The removal of wastes by the circulatory system in conjunction with the excretory system.
Term
What is plasma?
Definition
The liquid component of blood.
Term
Plasma is what percent water?
Definition
91% or 92%
Term
What is the first component of homeostasis?
Definition
The balance of the concentration of oxygen and carbon dioxide. Oxygen serves as the final acceptor for electrons removed in oxidative reactions. Co2 is the by-product of many reactions.
Term
What is the second component of homeostasis?
Definition
maintaining the pH of the internal environment?
Term
What is the third component of homeostasis?
Definition
Concentration of nutrients, waste products, salts, and other electrolytes.
Term
What is the fourth component of homeostasis?
Definition
The volume and pressure of interstitial (extracellular) fluids.
Term
How does your body maintain homeostasis?
Definition
It coordinates the activities of organ systems.
Term
What are the 11 organ systems?
Definition
Nervous, Endocrine, Muscular, Skeletal, Integumentary, Circulatory, Lymphatic, Respiratory, Digestive, Excretory, Reproductive.
Term
What are the two major control organ systems?
Definition
Nervous and Endocrine.
Term
What is an example of how body systems contribute to homeostasis?
Definition
Exercise: Muscles use more oxygen and produce more Co2.

1) Intrinsic controls cause dilation of the blood vessels.
2) This allows more blood into those active areas of the muscles to bring in more O2 and take away CO2.
3) Avtive hyperemia: increased blood flow through a tissue associated with increased metabolic activity.
Term
What is a vasodilator?
Definition
An intrinsic control; chemical mediators that result in the dilation of blood vessels. (Nitric Oxide).
Term
How does Nitric Oxide work as a vasodilator?
Definition
1) When blood oxygen levels fall, endothelial cells in blood vessel walls synthesize and release NO.
2) NO activates an enzyme that relaxes neighboring smooth muscle.
3) This dilates blood vessels and increases blood flow.
Term
What is the primary mechanism of homeostasis?
Definition
Negative feedback.
Term
What is negative feedback?
Definition
A stimulus triggers a response. This response cancels the effect of the original change. Example: Stop the synthesis of an enzyme by the accumulation of the products of the enzyme-mediated reaction.
Term
What are the five major factors in homeostasis?
Definition
Stimulus, Sensor, Integrator, Effector, and Response.
Term
How does Negative Feedback interrupt homeostasis?
Definition
The response (or last step of the system) counteracts the original change: IE the Stimulus no longer affects the sensors. Example: Temperature regulation.
Term
What is a sensor?
Definition
AKA a Sensory Receptor: Nerve endings that detect a change in factors such as pressure, temperature, pH, concentrations of molecules, etc. In response to this change, initiates sensory transduction.
Term
What happens in sensory transduction?
Definition
1)Stimulus (or change) is converted into an action potential (AP).
2) Action potential is transmitted along axons towards the central nervous system (CNS) where it is integrated.

Example: Sensory cells (rods and cones) in the retina convert the physical energy of light signals into electrical impulses (APs) that travel to the brain.
Term
What are baroreceptors?
Definition
Neurons or nerve endings in the walls of the atria of the heart, the aortic arch, and the carotid sinuses that detect the amount of stretch in vessel walls. They are sensitive to changes in blood pressure.
Term
What do baroreceptors do?
Definition
1)They send signals (APs) to the brain stem.
2) The brain stem sends signals via autonomic nervous system to elicit changes.
3) Example of signals: Baroreceptors decrease their rate of firing (APs) when blood pressure drop.s
4) This stimulates mechanisms (such as changes in heart rate, vasodilation, or vasoconstriction) so that the body can adjust and adapt to the change in pressure.
Term
Signals from the baroreceptors can do what to the rate and force of the heartbeat?
Definition
They can adjust it. High blood pressure = slower and less forceful heart beat.
Term
Chemoreceptors are found where?
Definition
In the aorta and carotid arteries.
Term
What do chemoreceptors do?
Definition
1) They detect O2 content in the blood.
2) If O2 content falls below normal, chemoreceptors send signals (APs) to the brainstem.
3) The brainstem integrates this information with the information from the baroreceptors.
4) The brainstem sends the signal to increase the rate and force of the heartbeat.
Term
What is an osmoreceptor?
Definition
Involved with the water and electrolyte homeostasis.
Term
What is a thermoreceptor?
Definition
Sensor in the skin and hypothalamus that detect changes in the temperature of the body and brain.
2) The hypothalamus is the integrator: it compares the change to the set point (normal -- which is 37 degrees C).
Term
What happens with Vasoconstriction?
Definition
1) Blood vessels in the skin constrict (get smaller).
2) Blood flow is reduced.
3) This means that less heat is conducted from the blood through the skin to the environment.
4) HEAT LOSS IS REDUCED.
Term
When might vasodilation occur in the body?
Definition
When you feel hot + when you exercise a lot. Increase heat loss.
Term
What organ triggers effectors that dilate or constrict blood vessels in the skin?
Definition
Hypothalamus.
Term
What happens in a fever?
Definition
Your hypothalamus purposely sets the temperature set point (stasis) higher. Bacteria or viruses don't survive as well at higher temperatures. Also, some immunological reactions may work better at higher temperatures.
Term
What are other examples of temperature regulation?
Definition
Sweating, Shivering, Behavior.
Term
pH Homeostasis
Definition
Learn it -- Powerpoint chart!
Term
Summarize Negative Feedback
Definition
1) A factor affects body's internal environment.
2) This elicits a change.
3) The change is detected by receptors.
4) The receptors send out nerve or hormonal messages.
5) The messages are received by effectors.
6) The effectors trigger a counteractive response.
7) The internal environment returns to the norm/set point.
Term
What is a positive feedback Mechanism?
Definition
A change in an internal or external environmental condition that INTENSIFIES the condition. This DOES NOT RESULT IN HOMEOSTASIS.

Example: Childbirth. The fetus pushes against the cervix to cause the cervix to stretch. Mechanoreceptors sense the stretch and send a signal to the hypothalamus which releases oxytocin. Oxytocin triggers stronger contractions which repeat the feedback loop.
Term
Structure and Function of Body Systems.
Definition
Organ Systems > Organs. Organs > Tissues. Tissues > Cells.
Term
What are the four basic tissues?
Definition
1) Epithelial
2) Connective
3) Muscle
4) Nervous
Term
What does Epithelial tissue do?
Definition
1) Lines body structures and cavities. Forms protective, secretory and absorptive covering.
Term
What does Connective tissue do?
Definition
Support.
Term
What does Muscle tissue do?
Definition
Movement.
Term
What does Nervous tissue do?
Definition
Transmit information.
Term
What are the three shapes of epithelial cells?
Definition
Squamous, Cuboidal, Columnar.
Term
Where are Squamous epithelium cells located and what is its function?
Definition
1) Walls of blood vessels, air sacs, and lungs.
2) Diffusion
Term
Where are cuboidal epithelial cells found and what is their function?
Definition
1) Glands and tubular parts of nephrons, or kidneys.
2) Secretion, absorption.
Term
Where are Columnar epithelial cells located, and what is their function?
Definition
1) Lining of the gut and respiratory tract.
2) Secretion, absorption.
Term
What is the difference between Epithelium and Endothelium?
Definition
Endothelium is the thin layer of cells that line the interior surface of blood vessels.
Term
What are the 6 types of connective tissue?
Definition
1)Cartilage
2)Blood
3) Fat (adipose tissue)
4) Bone
5) Loose connective tissue
6) Fibrous connective tissue.
Term
What are the three types of Muscle?
Definition
Skeletal, Cardiac, Smooth. They all look different.
Term
A nerve is made up of what?
Definition
Nucleus, Dendrites, Cell body, Axo, and Axon terminals. Axon terminals are sensors.
Term
What kind of receptors does the skin have?
Definition
Mechanoreceptors -- pacinian corpuscle. Detects touch and vibrations.
Term
In some negative feedback mechanisms in animals, integrating neurons in the brain are directly stimulated by signals from the _______.
Definition
Hypothalamus.
Term
The body only acts if it senses a change in the body away from _______.
Definition
a set point.
Term
What are four functions of the epithelial cell?
Definition
Filtration, Gas exchange, body cavity lining, external barrier.
Term
Why are specialized cells and tissues important to multicellular animals?
Definition
Specialization greatly increases the efficiency of important metabolic functions.
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