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menedlian genetics: classic F2 generation BbxBb |
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one locus affects two or more traits |
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alleles at one locus affect the expression of alleles at a different locus. |
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Two or more loci are on the same chromosome. |
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Example of pleiotrophy in cats can cause? |
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deafness & White pigments |
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control development of pigments and electric signals |
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Calculate allele frequencies(A,a) by proportion P H Q (100,90,10) |
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A=100/200+45/200=.725 a=10/200+45/200=.275 |
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3 equations used to calculate allele frequencies used before: Recall it them! p=? q=? ?=? |
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KK-128 Kk-70 genotype frequencies? kk-18 |
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128/216=.59 70/216=.33 18/216=.08 |
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What happens to p& q in random mating |
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Random mating, what is P, H, Q f(A)=p=.55 f(a)=q=.45 using equations: pxp= 2pq= qxq= |
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P=.3025 H=.495 Q=.2025 sum of All=1 |
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know the difference between number and proportions: AA=100 Aa=75 aa=25 calculate number of alleles: calculate proportion of alleles: |
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#:A=275 a=125 T=300
pro: P=.5 H=.375 Q=.125 T=1 |
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possible confusion when calculating H |
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use small q and p don't use big Q and P H= 2pq |
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what does the Hardy-Weinberg Equilibrium principle state? |
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states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences (Wikipedia) |
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What are some evolutionary influences? |
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Migration mutation and selection |
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understanding of this statement. |
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“Allele frequencies and genotypic frequencies remain constant and genotypic frequencies are determined by allele frequencies” when the H-W eqilibrium is used. |
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