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the movement of drug from the dosage formulation to the blood |
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the movement of drugs from an area of lower concentration to an area of higher concentration; requires cellular energy |
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drugs that activate receptors to accelerate or slow normal cellular function |
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drugs that bind with receptors but do not activate them |
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the relative amount of an administered dose that reaches the general circulation and the rate at which this occurs |
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the study of factors associated with drug products and physiological processes, and the resulting systemic concentration of drugs |
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the comparison of bioavability between two dosage forms |
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a term sometimes used to refer to all the ADME processes together |
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the time the drug processes are above the MEC |
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the processs of metabolsim and excretion |
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the transfer of drugs and their metabolites from the liver to the bile in the gall bladder, then into the intestine, and then back into circulation |
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a complex protein that catalyzes chemical reactions |
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the increase in hepatic enzyme activity that results in greater metabolism of drugs |
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the decrease in hepatic enzyme activity that resuylts in reduced metabolism of drugs |
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the substantial degradation of an orally administered drg caused by enzyme metabolism in the liver before the drug reaches the systemic circulation |
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the time a drug will stay in the stomach before it is mptied into the small intestine |
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the blood filtering process of the nephron |
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capable of associating with or absorbing water |
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water repelling; cannot associate with water |
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when differnet molecules associate or attach to each other |
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