Term
|
Definition
Gram - like, thin and doesn't stain well
Spirochete
Flagella |
|
|
Term
|
Definition
| Hyaluronidase (hydrolyzes EMC of CT to spread) |
|
|
Term
| Trep Pallium Transmission |
|
Definition
| Close contact, across mucous |
|
|
Term
|
Definition
| Human Mucosal surface (only pathogenic and never normal flora) |
|
|
Term
|
Definition
| Throat culture on selective medium |
|
|
Term
|
Definition
Primary syphilis: painless, crusty pustule, clears after several weeks
Secondary syphilis: lesions throughout body, palms/feet
Tertiary syphilis: immune complexes form causes tissue damage
Neurosyphilis: can infect CSF and CNS
Congenital syphilic: cross placental barrier |
|
|
Term
|
Definition
| Penicillin (only primary and secondary) |
|
|
Term
| Borrelia Burgdorferi Apperance |
|
Definition
Gram - like, but no LPS, Krebs or ETC
Spirochete
Flagella
Linear genome
Iron Abstient |
|
|
Term
| Borrelia Burgdorgeri Virulence |
|
Definition
OspA: sticks to midgut of tick
OspC: targets bacteria to salivary glands
OspE: inhibits complement
Expression of surface proteins is temp-regulated (to detect human vs tick) |
|
|
Term
| Borrelia Burgdorferi Reservoir |
|
Definition
| Animals (rodents, ticks, deer) (saliva) |
|
|
Term
| Borrelia Burgdorferi Diseases |
|
Definition
Stage 1: Skin infection from tick bite, red spot = "bulls-eye rash"
Stage 2: systemic infection, arthritis if joint infected
Stage 3: chronic, autoimmunity, inflamm, aspetic menigitis
Lyme disease |
|
|
Term
|
Definition
Don't get bit
Antibiotics (only stage I and II) |
|
|
