Term
|
Definition
-gram-positive cocci
-catalase-negative
-Beta-hemolytic
-M proteins interfere with phagocytosis
-Streptolysin S + O
-Erythrogenic exotoxins (scarlet fever rash)
-Nonantigenic antiphagocytic hyaluronic capsule
-causes: pharyngitis, Scarlet fever, Rheumatic fever
-S to Bacitracin |
|
|
Term
| Rheumatic Fever 1) predisposed by 2)hallmark lesion/result 3)MOA |
|
Definition
1. Group A strep throat infection
2. dmged heart mm with MITRAL STENOSIS
3. Anti-strep Ab cross-react with sarcolemmal mm + kidney tissues ->inflam |
|
|
Term
| What shape is H. influenzae in CSF? |
|
Definition
| gram-negative coccobacilli; typically bacilli |
|
|
Term
| HiB primarily causes what three diseases in unvaccinated children? |
|
Definition
1. Septicemia
2. Meningitis
3. Epiglottitis |
|
|
Term
| H influenzae pathogenicity hails from what three factors? |
|
Definition
1. Polysaccaride capsule: inhibits phagocytosis
2. IgA protease: Increased colonization
3. Endotoxin: triggers macros |
|
|
Term
| C. diptheriae uses what two types of cultures? |
|
Definition
Tellurite- (gray to black colonies)
Loffler's- metachromatic VOLUTIN granules |
|
|
Term
|
Definition
1. Targets upper resp, heart, nerve cells
2. Shuts down host protein synthesis by ADP ribosylating EF-2
3. produced only by beta-corynephage strains |
|
|
Term
|
Definition
|
|
Term
|
Definition
-ulcerating, necrotizing gingivitis
-caused by fusobacterium nucleatum
-known as TRENCH MOUTH |
|
|
Term
| Leading cause of bacterial meningitis in infants and elderly |
|
Definition
|
|
Term
|
Definition
-gram positive
-alpha hemolytic
-diplococci
-optochin sensitive
-fermentates inulin
-antiphagocytic capsule
-diseases: pneumonia; septicemia + otitis media in infants |
|
|
Term
| Mycoplasma pneumoniae pathogenicity is due to what three things? |
|
Definition
1. P1 protein attaching the bacteria to mucosal cells
2. Elaboration of H2O2 -> hacking cough
3. Ag of membrane fusing with host-> autoimmune rxn |
|
|
Term
| Primary causative agent for atypical pneumonia? |
|
Definition
Mycoplasma pneumoniae
Presents as: gradual fever, headache, malaise, nonproductive cough; infiltrative pattern |
|
|
Term
|
Definition
-Dieterle's silver stain +
-gram-negative bacilli
-catalase positive
-facultative, intracellular |
|
|
Term
| L. pneumonphila pathogenicity is due to? |
|
Definition
1. Does not activate the alternate C' pathway
2.Elaborates CYTOTOXIN- interferes with O2-dependent phagocytosis
3. Beta-lactamases
4. Endotoxin |
|
|
Term
| TX of Legionnaire's and Pontiac fever is? |
|
Definition
|
|
