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Bacterial Pneumonia Clinic
Bacterial Pneumonia Clinic
67
Medical
Professional
03/10/2009

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Term
inflammation fo the lung parenchyma caused by an infection (bacteria, virusesm, fungi)
Definition
pneumonia
Term
An abnormal infiltrate is required on ______ ______. This is required for diagnosis of pneumonia
Definition
chest radiograph
Term
symptoms of pneumonia
Definition
cough
dyspnea
fever
tachypnea
hemoptysis
pleuritic chest pain
myalgia
gi symptoms
rales rhonchi weezing
egophony

sensitivity of clinical criteria is no greater than 50 percent.
Term
Types of pneumonia
Definition
community acquired pneumonia (non health care)
nosocomial mneumonia (health care)
aspiration pneumonia (usually anerobes or a mix)
Term
Pneumonia is the _____ leading cause of death in the USA
Definition
7th
Term
Rates of dath have increased by ___ percent in the last 20 years.
Definition
60 percent
Term
Annually greater than 5 million cases of pneumonia inthe us result in
Definition
more than one million hospitalization 80 thousand deaths.
Term
What is the most common cause of death in teh united states? What is the most common infectious disease cause of hospitalization and death?
Definition
1) heart disease
2) penumonia
Term
typical penumonia
Definition
caused by pneumococcus and staphylococcus
Term
atypical pneumonia
Definition
caused by
legionella
mycoplasma
chlamyophilia
Term
atypical pneumonia
Definition
caused by
legionella
mycoplasma
chlamyophilia

mycobacterial
anaerobes
viral
fungal(coccidioides)
parasitic
Term
What percent of community aquired pneumonias have unknown etiology
Definition
40-50 p ercent
Term
The most common cause of pneumoniae?
Definition
streptococcus
Term
a typical pneumonias
Definition
chlamidyophilic pneumonia
legionella
mycoplasma pneumonia
Term
other causes of pneumonia
Definition
h. influenzae
moraxella catarhallis
staph aureus
gram negative rods
mycobacter
anaerobes
Term
mycoplasma
Definition
no cell walls
Term
mycobacter
Definition
gram + slightly
acid fast bacillus staining
Term
pathogenesis of pneumonia
Definition
lung parencyma are usually sterile
pneumonia develops if host defenses are absent or overwhlmed
Term
Microaspiration of oropharyngeal secretion colonized with pathogens
Definition
the most common route of getting pneumonia
Term
gross aspiration of gastric contents with_______ or__________. This can be caused by damage to _________.
Definition
enteric gram - rods
anaerobes
CNS
Term
_______ is a viable very transmisable route of spreading pneumonia especially m. tuberculosis, legionella
Definition
Term
Staph aureus during endocarditis is an example of heamtogenous spread.
Definition
if you have a heart valve, bacteria lodges elsewhere.
Term
Congiguous spread from another site example
Definition
Liver abscess, penetrating trauma.
Term
Infection within alveoli
Definition
bacteria enter the cell
bacterial defenses allow it to survive
multiply
tissue injury
vascular permeability
increases
akveolar macrophages recruited to teh area of inflmation
large groups of alveolifileld with inflamatory exudates appear as pacities or consolidation on chest radiographs.
Term
Risk factors for pneumonia
Definition
age
dentition
smoking
heavy alcohol intake
contact with children
copd
congestive hear gailure
diabetes mellitus
malnutrition
malignancy
Term
risk factors for getting drug resistant spneumoniae
Definition
greater than 65 less than 5
recent antibiotics or hospitalization
alcoholism
immune suppression
cardiopulmonary
exposure to child
Term
risk factors for enteric gram negative rods (klebsiella)
Definition
nursing home resident
comorbid cardiopulmonary disease
recent antibiotics
Term
risk factors for p aurigunosa
Definition
structural lung diseases
steroid use
recent antibiotics
malnutrition
Term
staph aureus risk factors
Definition
recent influenza
co morbid cardiopulmonary diseases
Term
asplenia you are at risk for
Definition
h. influenza
s. pneumonia
Term
cystic fibrosis you are at risk for
Definition
pseudonomas
burkholderia cepacia
Term
influenza outbreak you are at risk for
Definition
staph aureus
strep pneumonia
Term
Treatment of severe CAP
Definition
treatment involves a combination of iv antibiotics 1-2 weeks

-beta lactam
-fluoroquinolne
-macrolide
Term
what covers methicillin resistant s. aureus?
Definition
vancomycin
Term
supportive care
Definition
ventilation
supplemental oxygen
blood pressure support
cardiovascular monitoring
Term
complications of pneumonia
Definition
bacteremia and sepsis
pleural effusion
empysema
lung abscesses
Term
parapneumonic effusion occurs is ___ percent of pneumonia. Usually resolve with antibiotic treatment What percent of s. pyogenes? S pneumonia?
Definition
40 percent.
90 percent in strep pyogenes
10 percent in s.pneumonia
Term
THoracentessis may be needed
Definition
small amount for diagnosis on parapneumonic effusion

large amoutn for treatment.
Term
Empynema
Definition
colelction of pus in the collected space.
Term
How do you diagnose an empynema?
Definition
you need to see a visible yellow pus with a high WBC count of greater than 50000.
Term
How do you heal an empynema?
Definition
drain it.
antibiotics.
Term
Pulmonary abscesses cause by
Definition
complication of pneumonia due to
anaerobic/mixed flora or bactremia.
right middle lobe or lower lobe
Term
in young healthy patient, mild case of pneumonia. more common cause
Definition
mycoplasma
chlamydophila
Term
Why do we call something atypical
Definition
not normally cultured
cannot be treated with penicillin
a typical cxr findings
cxr can't be used to distinguish the ytype of pneumonia
Term
treatment of mild cap (walking penumonia)
Definition
floriquinine
macrolides
tetracyclines
Term
How do we diagnosespneumonia pathogen
Definition
sputum gram staina nd culture
pleural fluid culture
blood cultures
pneumococcal and legionella urine
consider HIV testingafb stain if you consider mycobacter
antibidy titer
Term
gram stain
Definition
crystal violent
idodine
decolor with alochol
counterstain
Term
sputum gram stain
Definition
sputum gram stain revelaing a single prdominant organizim can help establish the etiolgoy and guide therapy.

should be deep cough

should be obtaiend prior to antibiotic treatment

less than ten epithelial cells greater than 25 pmns per low power field

cant use if greater htan 10 epithelial cells
Term
sputum gram stain
Definition
sputum gram stain revelaing a single prdominant organizim can help establish the etiolgoy and guide therapy.

should be deep cough

should be obtaiend prior to antibiotic treatment

less than ten epithelial cells greater than 25 pmns per low power field

cant use if greater htan 10 epithelial cells
Term
Which bugs can you do a urine antigen test?
Definition
pneumococcal
legionella
Term
s. pneumonia gram stan
staph aureus
Definition
gram positive lacet chapped
cocci in groups
Term
blood and sputum cultures are recommended for all patients with pneumonia (true/false)
Definition
false
recommeded only in cases of failed antibiotics
immunosupression chronic liver or lung disease
asplenia
recent travel
pleural effusion
Term
chest x ray is recommended for all patients with sspected pneumonia
Definition
true posterior and lateral view
Term
radiography lags clinical improvment by
Definition
two to four weeks.
Term
possible false negative xray
Definition
netropenia
dehydrated
pneumocystic jirovesi
Term
CT has better resolution than xray (true/false)
Definition
true
Term
In ER how many blood vials are drawn
Definition
4 1aerobic 1 anaerobic frome ach of two viens sent to micro
Term
microdilution can test for susceptibility to various antibiotics
Definition
you can see which drugs it is resistant to
Term
when should you administer antibiotic therapy?
Definition
within 4-8 hours of diagnosis.
Term
What is the basic treatment question when managing a case of CAP
Definition
should i start with foriquinone or a macrolide along with Beta lactam or not?
Term
What is a PORT score?
Definition
It predicts mortality and need for hospitalization int he case of pneumonia
Term
Outpatient CAP patient
Definition
ML or FQ or doxycycline
Term
non-ICU patient CAP what do you treat?
Definition
FQ or ML plus 3rd gen cephalosporin
Term
ICU patient with CAP treatment
Definition
anti psudomonal cephalosporin pplus FQ or ML
Term
mycin-
Definition
macrolide
azithromycin
clarithromycin
Term
oxacin
Definition
FQ
moxifloxican
levofloxican
Term
2 pneumococcal vaccines
Definition
90 types ofpneumonia
two vaccines
polysaccharide 23 valent
reduces risk by 50-60 percent
85-90 percent of invasive serotypes covered

doesn't work against non bacteria
but reduces mortality by 40 percent

23 valent polysaccharide
recommended over 65
cardiomyopathy


7 valent is for kids reduces rosk to kids by 90 percent
2,4,6

alcoholism
immunocompromsed
long term facility
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