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Bacterial infections of CNS
Test 2 Sem 2
27
Medical
Graduate
02/06/2011

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Cards

Term
bacterial meningitis primarily effects what age group of people?
Definition
adults
Term
What organism causes the most cases of bacterial meningitis in the US?
Definition
S. pneumoniae
Term
What organism primarily causes meningitis in complement deficiency pts?
Definition
Neisseria meningitidis
Term
What organism primarily causes meningitis in immunocompromised and elderly?
Definition
Listeria monocytogenes
Term
What are the most common clinical features of bacterial meningitis? (4)
Definition
1) headache
2) fever
3) nuchal rigidity
4) neurologic findings
Term
What is kernig sign?
Definition
when hip is flexed at 90 degrees, extension of the knee meets resistance at 135 degrees
Term
brudzinski sign is what?
Definition
passive neck flexion causes knee and hip flexion
Term
What is the most important diagnostic test for bacterial meningitis?
Definition
cerebrospinal fluid exam for WBC, proteins, and glucose levels
Term
When should you CT scan a patient before LP? (5)
Definition
1) brain stem herniation
2) dilated, fixed pupils
3) Cheyne-Stokes respirations
4) decrebrate posturing
5) hemiplegia and coma
Term
What is the opening pressure for LPs?
Definition
180mm H2O
Term
What is the CSF protein, glucose, and WBC counts in the majority of patients?
Definition
CSF protein >40mg/dl
Glucose <40mg/dl
CSF WBC >100 mm
Term
What is the most important therapeutic measure for bacterial meningitis?
Definition
prompt initiation of IV antibiotics after LP
Term
What are the most frequent neurological complications of meningitis?
Definition
seizures and altered mentation
Term
What is the most common cause of posttraumatic bacterial meningitis?
Definition
S. pneumoniae
Term
What is very accurate in diagnosing fistulas found in bacterial meningitis?
Definition
MRI cisternography
Term
What are the most common organisms found in bacterial abscesses?
Definition
aerobic, microaerophilic, and anaerobic streptococci
Term
What do you use to treat bacterial abscesses?
Definition
ceftriaxone and metronidazole can use dexamethasone for cerebral edema
Term
What are the most common neurologic problems seen with bacterial abscesses?
Definition
focal seizures
Term
What is the most common bacteria involved with spinal epidural abscesses?
Definition
S. aureus
Term
What is the most common symptom of spinal epidural abscesses?
Definition
back pain over affected area
Term
neurosurgery is important with spinal epidural abscesses to what?
Definition
remove pus and granulation tissue-decompression laminectomy
Term
antibiotic tx for spinal epidural abscesse?
Definition
coverage for gram-negative bacilli (gentamicin/3rd gen cephalosporin) and one active against S. aureus (nafcillin)
Term
Subdural empyema are most commonly a complication of what?
Definition
sinusitis
Term
How do you treat subdural empyemas?
Definition
removal of pus through craniotomy, ceftriaxone and metronidazole
Term
Cavernous sinus thrombophlebitis usually results from what organism from what areas?
Definition
S. aureus from paranasal or facial skin infections
Term
lateral sinus thrombophlebitis is almost always a complication of what?
Definition
mastoiditis
Term
What mental changes are seen in 80% of meningitis patients, especially the elderly
Definition
confusion, stupor, and coma
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