Term
|
Definition
p.o. macrolide (azithromycin or clarithromycin)
NB: "buy AT 30, CELL at 50."
buy
A=aminoglycosides,
T=tetracyclines
30=30S.
C=chloramphenicol,
E=erythromycin (macrolides),
L=Lincosamides (clindamycin)
L = cLindamycin
at 50 |
|
|
Term
| CAP outpatient with structural lung disease (COPD, asthma) |
|
Definition
| p.o. "respiratory" FQ = levofloxacin or moxifloxacin (a "respiratory FQ" is a FQ good activity against strep pneumo) |
|
|
Term
| pneumonia (inpatient) (CAP that does not respond to outpatient tx with clari, or CAP in an untreated patient admitted to the hospital) |
|
Definition
i.v. ceftriaxone or i.v. cefotaxime
(i.e. a 3rd gen cephalosporin = Gram '-' coverage > G '+'))
PLUS i.v. or p.o azithromycin (macrolide) or
i.v. moxifloxacin(4th gen FQ) or levofloxacin (2nd gen FQ)
NB: "buy AT 30, CELL at 50."
buy
A=aminoglycosides,
T=tetracyclines
30=30S.
C=chloramphenicol,
E=erythromycin (macrolides),
L=linezolid?,
L = cLindamycin
at 50
|
|
|
Term
| inpatient pneumonia in a patient with PCN allergy |
|
Definition
| i.v. moxifloxacin or levofloxacin (fq's) |
|
|
Term
| hospital-acquired (nosocomial) pneumonia |
|
Definition
| i.v. piperacillin - tazobactam, or i.v. cefepime |
|
|
Term
| Strep pneumo (inpatient, identified by culture) e.g., meningitis, pneumonia |
|
Definition
| i.v. pen G send home on p.o. amoxicillin |
|
|
Term
| Pen G resistant strep (low level of PCN resistance) |
|
Definition
i.v. cefotaxime, or i.v. ceftriaxone
(both 3rd gen cephalosporins) |
|
|
Term
| MDR strep pneumo (including high-level PCN-resistant) MDR strep pneumo includes isolates previously known as PRSP (penicillin-resistant Streptococcus pneumoniae), and are strains resistant to two or more of the following antibiotics: penicillin, 2nd generation cephalosporins, e.g., cefuroxime, macrolides, tetracyclines and trimethoprim/sulfamethoxazole. |
|
Definition
i.v. vancomycin,
or
i.v. moxifloxacin or high-dose i.v. levofloxacin (fluoroquinolones) |
|
|
Term
|
Definition
i.v. azithromycin(macrolide),
or
i.v. levofloxacin or moxifloxacin(fq)
macrolide (azithromycin or clarithromycin)
NB: "buy AT 30, CELL at 50."
buy
A=aminoglycosides,
T=tetracyclines
30=30S.
C=chloramphenicol,
E=erythromycin (macrolides),
L=Lincosamides (clindamycin)
L = cLindamycin
at 50
|
|
|
Term
|
Definition
trimethoprim-sulfamethoxazole(larger than normal doses)
NB: this has the same MOA as pyrimethamine-sulfafiazine acting on the same pathway enzymes dihyropteroate synthetase and dihydrofolate reductase |
|
|
Term
|
Definition
i.v. or p.o. clindamycin
macrolide (azithromycin or clarithromycin)
NB: "buy AT 30, CELL at 50."
buy
A=aminoglycosides,
T=tetracyclines
30=30S.
C=chloramphenicol,
E=erythromycin (macrolides),
L=Lincosamides (clindamycin)
L = cLindamycin
at 50
|
|
|
Term
| outpatient URI in patient with PCN allergy |
|
Definition
| p.o. macrolide (clarithromycin, or azithromycin) |
|
|
Term
| beta-hemolytic strep (e.g., pharyngitis, tonsillitis) |
|
Definition
| i.v. pen G (inpatient) p.o. amoxicillin (outpatient) |
|
|
Term
| beta-hemolytic strep in patient with PCN allergy |
|
Definition
| p.o. clindamycin (textbooks) p.o. FQ = levo or moxi (real world) |
|
|
Term
prophylaxis for
beta-hemolytic strep |
|
Definition
| i.m. procaine pen G, or i.m. benzathine pen G |
|
|
Term
| infected diabetic foot ulcer |
|
Definition
| i.v. piperacillin-tazobactam |
|
|
Term
| primary/secondary syphilis |
|
Definition
| i.m. benzathine penicillin |
|
|
Term
|
Definition
|
|
Term
|
Definition
| single dose p.o. cefixime, or i.m. ceftriaxone(in the ER, about 50% ofpatients will receive p.o. cefixime and 50% will receive i.m. ceftriaxone - it hurts!) |
|
|
Term
Community acquired meningitis
(empiric therapy when the bug is unknown), patient is one month to 50 y.o. |
|
Definition
i.v. ceftriaxone or i.v. cefotaxime
PLUS
i.v. vancomycin |
|
|
Term
community acquired meningitis empr ther
for
younger than one month or older than 50 |
|
Definition
i.v. ceftriaxone or i.v. cefotaxime + vanc
PLUS
i.v. ampicillin to cover Listeria |
|
|
Term
| bacterial meningitis where the bug has been identified (H. flu, strep pneumo, or Neisseria spp. identified by culture |
|
Definition
i.v. cefotaxime or
i.v. ceftriaxone |
|
|
Term
febrile neutropenia
(empiric therapy) |
|
Definition
i.v. pip-tazo or i.v. cefepime
PLUS
i.v. vanc to cover gram (+) bugs |
|
|
Term
| cellulitis (MSSA) inpatient |
|
Definition
i.v. oxacillin or i.v. nafcillin ($$$)
i.v. cefazoling (cheap) |
|
|
Term
| cellulitis (MSSA) outpatient |
|
Definition
p.o. dicloxacillin or
p.o. cephalexin |
|
|
Term
| cellulitis (MSSA) outpatiens with PCN allergy |
|
Definition
p.o. clindamycin or
p.o. doxycycline |
|
|
Term
|
Definition
p.o. clindamycin or
p.o. trim-sulfa or
p.o doxycycline |
|
|
Term
|
Definition
|
|
Term
| MRSA (hospital) in a patient who cannot tolerate vancomycin |
|
Definition
i.v. daptomycin or
i.v. or p.o. linezolid |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| Any SSTI caused by a "letter" strep |
|
Definition
i.v. pen G (inpatient)
p.o amoxicillin (outpatient) |
|
|
Term
|
Definition
p.o. amoxicillin or p.o. amoxacillin +clavulanate(augmentin) or p.o. cefdinir
clavulanate is a beta lactamase inhibitor (nothing kills like a beta lactam) |
|
|
Term
|
Definition
i.v. pip-tazo or
i.v. cefepime or
i.v. ceftazidime |
|
|
Term
| serious gram (-) infection in patients allergic to PCN's |
|
Definition
|
|
Term
| serious gram (-) infections (as empiric therapy) |
|
Definition
| antipseudomonal beta lactam PLUS an aminoglycoside |
|
|
Term
| surgical prophylaxis (not intra-abdominal) |
|
Definition
i.v. cefazolin (1st gen Cef G+>G-)
|
|
|
Term
| gut decontamination prior to GI surgery |
|
Definition
| p.o. neomycin (not abs from GI tract) |
|
|
Term
| perioperative prophylaxis for GI surgery |
|
Definition
| i.v. cefoxitin or i.v. cefotetan |
|
|
Term
| anaerobic infections (penetrating GI trauma, appendicitis, and lung abscesses |
|
Definition
|
|
Term
|
Definition
| i.v. cefoxitin or i.v. cefotetan PLUS i.v. doxycycline |
|
|
Term
|
Definition
| single dose i.m. ceftriaxone PLUS po metronidazole (2 weeks) PLUS po doxycycline (2 weeks) |
|
|
Term
| anaerobic infections in PCN allergic patients |
|
Definition
|
|
Term
|
Definition
| i.v. ampicillin, if amp res use i.v. vanc if vanc res use i.v. or p.o. linezolid |
|
|
Term
| ampicillin-resistant enterococcus |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| i.v. vancomycin (empiric therapy which should be adjusted based on culture results) |
|
|
Term
| C. dificile (pseudomembranous colitis) |
|
Definition
| p.o. metronidazole, if disease is severe use i.v. vancomycin |
|
|
Term
|
Definition
| p.o. doxycycline or P.o. macrolide |
|
|
Term
|
Definition
p.o. doxycycline(tetracycline)
or
p.o. macrolide(erythromycin or azithromycine) |
|
|
Term
|
Definition
| p.o. doxycycline (tetracycline) |
|
|
Term
|
Definition
| p.o. doxycycline (tetracycline) |
|
|
Term
|
Definition
|
|
Term
| diarrhea (Salmonella, Shigella, E. coli or campylobacter) |
|
Definition
p.o. ciprofloxacin
2nd gen fluoroquinolone |
|
|
Term
|
Definition
|
|
Term
| complicated UTI including UTI from a nursing home (empiric therapy) |
|
Definition
| i.v. cefotaxime or i.v. ceftriaxone or p.o. cefpodoxime |
|
|
Term
|
Definition
i.v. ceftriaxone or
i.v. cefotaxime
send home on p.o. cefpodoxime |
|
|
Term
|
Definition
|
|
Term
TB (positive sputum)
(mneumonic RIPE) |
|
Definition
all p.o.
rifampin
plus
isoniazid
pyrazinamide
ethambutol |
|
|
Term
|
Definition
all P.O.
rifabutin
plus
isoniazid
plus
pyrazinamide
plus
ethambutol |
|
|
Term
| Treatment of latent TB infection in patient with positive PPD but negative CXR and negative sputum |
|
Definition
p.o isoniazid or
p.o. rifampin |
|
|
Term
brucellosis
(often from eating unpasteurized cheese) |
|
Definition
p.o. doxycycline
PLUS
i.v. gentamicin |
|
|
Term
Mycobacterium avium
(AIDS patient) |
|
Definition
p.o. or i.v. macrolide
PLUS
ethambutol |
|
|
Term
|
Definition
p.o. minocycline or
topical clindamycin or
topical erythromycin |
|
|
Term
|
Definition
|
|
