Term
|
Definition
Direct M Ag
Use: postop ileus & urinary retention |
|
|
Term
|
Definition
Direct M Ag
Use: glauc, pupillary contraction, release of IOP |
|
|
Term
|
Definition
Direct M Ag
Use: stims sweat, tears, & saliva
Note: resistant to AChE |
|
|
Term
|
Definition
Direct M Ag
Mech: stims M in airway when inhaled
Use: challenge test for asthma dx |
|
|
Term
|
Definition
Indirect M Ag (Anticholinesterase)
Use: postop ileus & urinary retention; MG; postop reversal of NMJ block
Note: no CNS penetration (neo=no")" |
|
|
Term
|
Definition
Indirect M Ag (Anticholinesterase)
Use: MG (long-acting)
Note: no CNS penetration |
|
|
Term
|
Definition
Indirect M Ag (Anticholinesterase)
Use: MG dx (extremely short acting) |
|
|
Term
|
Definition
Indirect M Ag (Anticholinesterase)
Use: glauc & atropine OD (phys is for eyes")
Note: crosses BBB" |
|
|
Term
|
Definition
Indirect M Ag (Anticholinesterase)
Note: irreversibleUse: glauc |
|
|
Term
|
Definition
Irreversible non-comp AChE inhib -
others: malathion, sarin, soman
Antidote: atropine + pralidoxime (2-PAM) |
|
|
Term
|
Definition
AChE reactivator
Use: combo with atropine for O-P tox |
|
|
Term
|
Definition
M Antag
Use: mydriasis & cycloplegia
Tox: hot as a hare |
|
|
Term
|
Definition
M Antag
Use: mydriasis & cycloplegia |
|
|
Term
|
Definition
M Antag
Use: mydriasis & cycloplegia |
|
|
Term
|
Definition
| M AntagUse: Parkinson's dz |
|
|
Term
|
Definition
M Antag
Use: Motion sickness |
|
|
Term
|
Definition
|
|
Term
|
Definition
M Antag
Use: decr urinary urgency |
|
|
Term
|
Definition
M Antag
Use: decr urinary urgency |
|
|
Term
|
Definition
M Antag
Use: peptic ulcer tx |
|
|
Term
|
Definition
M Antag
Use: peptic ulcer tx |
|
|
Term
|
Definition
M Antag
Use: peptic ulcer tx |
|
|
Term
|
Definition
N Antag - non-depol Ganglionic blocker
Use: prevent vagal reflex response to changes in BP
Tox: orthostatic hypoTN, blurred vision, constip, sex dysfxn |
|
|
Term
|
Definition
N Antag - non-depol Ganglionic blocker
Tox: orthostatic hypoTN, blurred vision, constip, sex dysfxn |
|
|
Term
|
Definition
Direct sympathomimetic (α1, α2, β1, β2)
Use: anaphylaxis, open angle glauc, hypoTN
Note: low doses selective for β1 |
|
|
Term
|
Definition
Direct sympathomimetic (α1, α2 > β1)
Use: hypoTN |
|
|
Term
|
Definition
Direct sympathomimetic (β1, β2)
Use: AV block (rare) |
|
|
Term
|
Definition
Direct sympathomimetic (D1=D2 > β > α)
Use: shock (dil. renal bv), HF
Note: inotropic & chronotropic |
|
|
Term
|
Definition
Direct sympathomimetic (β1 > β2)
Use: shock, HF, cardiac stress test
Note: inotropic, not chronotropic |
|
|
Term
|
Definition
Direct sympathomimetic (α1 > α2)
Use: pupil dilation, vasoconstr, nasal decongestion |
|
|
Term
|
Definition
Direct sympathomimetic (β2 > β1) - Selective β2-Ag
Use: acute asthma |
|
|
Term
|
Definition
Direct sympathomimetic (β2 > β1) - Selective β2-Ag
Use: reduces premature uterine contractions |
|
|
Term
|
Definition
Direct sympathomimetic (β2)
Use: reduces premature uterine contractions |
|
|
Term
|
Definition
Indirect sympathomimetic
Mech: releases stored catecholamines
Use: narcolepsy, ADD |
|
|
Term
|
Definition
Indirect sympathomimetic
Mech: releases stored catecholamines
Use: nasal decongestion, urinary incontinence, hypoTN |
|
|
Term
|
Definition
Indirect sympathomimetic
Mech: catecholamines uptake inhibitor
Use: vasoconstr, local anesth |
|
|
Term
|
Definition
α2 Ag (symp antag)
Use: HTN (esp w/ renal dz - no decr. flow to kidney) |
|
|
Term
|
Definition
α2 Ag (symp antag)
Use: HTN (esp w/ renal dz - no decr. flow to kidney) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Nonselective α-blocker (irrev)
Use: pheo
Tox: ortho hypoTN, reflex tachy |
|
|
Term
|
Definition
Nonselective α-blocker (rev)
Use: pheo
Tox: ortho hypoTN, reflex tachy |
|
|
Term
|
Definition
α1-blocker - others: terazosin, doxazosin
Use: HTN, urinary retention in BPH
Tox: 1st-dose ortho hypoTN |
|
|
Term
|
Definition
α2-blocker
Use: depression
Tox: sedation, incr. Chl, incr. appetite |
|
|
Term
|
Definition
Nonselective β-blocker - others: timolol, nadolol, pindolol (partial - contra: angina)
Use: HTN, angina, MI (decr. mort), CHF, glauc (timolol - decr. aq. humor secr)
SE: impotence, exacerbation of asthma, CV effects, CNS effects (sedation)
Note: caution in DM |
|
|
Term
|
Definition
Selective β1-blocker - others: acebutolol (partial - contra: angina), esmolol (short-acting), atenolol, metoproplol
Use: HTN, angina, MI (decr. mort), CHF, glauc (timolol - decr. aq. humor secr)
SE: impotence, exacerbation of asthma, CV effects, CNS effects (sedation)
Note: caution in DM |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Anti-ACh
Mech: prevents ACh loading into vesicles |
|
|
Term
|
Definition
Anti-adrenergic
Mech: prevents loading of DA into vesicles |
|
|
Term
|
Definition
Anti-adrenergic
Mech: prevents vesicle release |
|
|
