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Definition
(hey Qutie) HAV1 M&M: H1, alpha1, V1, M1, M3; Gq stimulates PLC which converts lipids to PIP2 which is converted into IP3 (releases intracellular Ca) and DAG (stimulates PKC) |
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MAD 2's: M2, alpha2, D2; Gi inhibits adenylyl cyclase, which decreases cAMP and PKA |
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Better Be Division 1 (plus H2 V2); B1, B2, D1, H2, V2; Gs stimulates conversion of ATP to cAMP which increases PKA |
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Term
Muscarinic actions thru G proteins |
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Definition
M2= heart; inhibitory action so works thru Gi M1 (CNS and enteric) and M3 (glands, bladder, gut, ciliary) make you Queasy, work thru Gq |
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Term
Sensory fibers: C, A delta |
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Definition
pain and temp (smallest diameter); all skin, epidermis, some viscera; C is slower pain (unmyelinated) |
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hairless skin; fine touch, adapt quickly (onset/offset) |
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deep skin, ligaments, joints; Pa and Vibration; rapidly adapting so detects onset/offset |
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cup-shaped, encapsulated; hair follicles; static touch (shapes, edges, textures), adapt slowly |
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Sensory nerves ascend thru here ipsilaterallly after synapsing in DRG |
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Definition
inhibits assembly of ACh into NT vesicles in presynaptic terminal |
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Definition
prevents reuptake of choline (none to make ACh) |
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Definition
inhibits conversion of Tyrosine to DOPA (DOPA goes to DA) |
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Definition
inhibits NT vesicle assembly for NE |
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Definition
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Definition
NE itself (feedback inhibition via alpha 2 recs), M2 (inhibitory for heart), ACh (?), AngII (stim), amphetamines (stim) |
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Definition
inhibiting reuptake (like cocaine) |
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