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Autonomic Nervous System
Medical Physiology, SOM 2014
16
Medical
Professional
09/29/2010

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Cards

Term
Cholinergic neurotransmitter
Definition
Ach
Pre-ganglionic sympathetic & parasympathetic
post-ganglionic parasympathetics
(exception: sweat glands, sympathetic!)
Term
Adrenergic neurotransmitter
Definition
norephinephrine
post-ganglionic sympathetic
Term
a1

location?
G Protein?
Mechanism?
Definition
Location: smooth muscle (eye, bladder)

G Protein: Gq

Mechanism: stimulates PLC, increase IP3 and Ca2+ leading to contraction
Term
a2 receptors

location?
G protein?
Mechanism?
Definition
Location: gastrointestinal tract

G protein: Gj

Mechanism: inhibits adenyl cyclase, decrease cAMP
Term
B1 receptors

location?
G protein?
Mechanism?
Definition
location: Heart

G protein: Gs

Mechanism: simulates Adenyl cyclase, increases cAMP
Term
Muscarinic receptors
Definition
inhibitory in heart
excitatory in smooth muscle and glands
Term
Male sex organs
Sympathetic and parasympathetic actions
Definition
Sympathetic: ejaculation (alpha receptor)

Parasympathetic: Erection (Muscarinic)
Term
Bladder Sympathetic activity
Definition
Filling (L1-L3)
1. Relaxes detruser muscle (B2)
2. Contracts internal sphinctor (a1)
Term
Bladder Parasympathetic Activity
Definition
Emptying (S2-S4)
1. contracts detrusor muscle (muscarinic)
2. Relaxes internal sphincter (m)
Term
Pupil Sympathetic activity
Definition
Dilates Pupil
Contracts Radial Fibers (a1)
Term
Pupil parasympathetic activity
Definition
Pupil constricts
contracts circular fibers (muscarinic)
Term
Horner's Syndrome
Definition
loss of sympathetic activity
pupil constricts, droopy upper eyelid, lack of sweating on forehead, facial flushing
Term
Freys Syndrome
Definition
during healing of a deep wound to the parotid gland the parasympathetic fibers join the great auricular nerve. Saliva production (taste) leads to flushing/sweating.
Term
Referred pain
Definition
sympathetic afferents carry visceral pain and enter the dorsal horn with sensory afferents of the skin. They converge on the ame nerve cells in the spinal cord with pain from the body surface so the pain feels like its from the skin instead of from the visceral organs.
Term
Frey's Syndrome
Definition
while a wound to the parotid gland is healing, parasympathetic fibers join the great auricular nerve so that whenever the person salivates (taste), their face flushes.
Term
"Crocodile Tears"
Definition
When the facial nerve is healing, parasympathetic fibers join the lacrimal gland so whenever the person salivates they cry.
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