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Asthma
Test review
38
Medical
Undergraduate 3
02/28/2012

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Cards

Term
What happens during an acute asthma attack?
Definition
 The smooth muscles surrounding the small airways constrict
Term
The smooth muscle may increase to ______ times their size.
Definition
3X
Term

If chronic inflammation develops over time, the anatomic alterations become _______________.

Definition
 Irreversible, resulting in loss of airway caliber
Term

What are the major pathologic or structural changes observed during an asthmatic episode?

Definition
Smooth muscle constriction of the bronchial airways (bronchospasm), bronchial wall inflammation, excessive production of thick, whitish bronchial secretions, mucus plugging, hyperinflation of alveoli (air trapping), In severe cases, atelectasis caused by mucus plugging
Term

Asthma is found in what percentage of adults?

Definition
3-5% Children? 7-10%
Term

What percentage of individuals develops asthma before the age of ten?

Definition
50%
Term

What are the two major types of asthma?

Definition
Extrinsic and intrinsic
Term

According to GINA, what are the 2 categories of risk factors for asthma?

Definition
(1)the risk factors with which one is born that cause the development of asthma (e.g.,genetic factors or sex), and (2)the risk factors that trigger asthma symptoms (e.g., domestic mites, furred animals, cockroach allergen, fungi, molds, infections, tobacco smoke)
Term

What is extrinsic asthma?

Definition
When an asthmatic episode can be clearly linked to exposure to a specific allergen (antigen), the pt is said to have extrinsic asthma
Term

An excessive amount of what antibody is present in individuals with extrinsic asthma?

Definition
 Immunoglobulin E (IgE)
Term

Is there a genetic link to extrinsic asthma?

Definition
Yes
Term

Which type of asthma often disappears after puberty?

Definition
Extrinsic
Term

The early asthmatic response begins within minutes of exposure to an inhaled antigen and resolves in approximately 1 hour.  What is the late asthmatic response?

Definition
Begins several hours after exposure to an inhaled antigen but lasts much longer. The late asthmatic response may or may not follow an early asthmatic response.
Term

What is an early asthmatic response followed by a late asthmatic response called?

Definition
Biphasic response
Term

What is occupational asthma? .

Definition
Asthma caused by exposure to an agent encountered in the work environment
Term

Occupational asthma is seen primarily in what patient population?

Definition
adults
Term

What is intrinsic asthma?

Definition
When an asthmatic episode cannot be directly linked to a specific antigen or extrinsic inciting factor, it is referred to as intrinsic asthma
Term

Are their IgE levels elevated? (Intrinsic asthma pts)

Definition
No
Term

Is there a genetic link to intrinsic asthma?

Definition
No
Term

At what age does intrinsic asthma usually develop?

Definition
 After age 40
Term
What are other bold printed risk factors for intrinsic asthma?
Definition

Obesity; Sex (male sex is a risk factor for asthma in children, up to age 14 the prevalence of asthma is nearly twice as great in boys than girls. By adulthood, the prevalence is greater in women than in men); Infections; Exercise-induced asthma; Outdoor & indoor air pollution; Drugs, food additives, and food preservatives; Gastroesophageal reflux; Sleep (nocturnal asthma); Emotional stress; Perimenstrual asthma (catamenial asthma)

Term

As much as _______% of the asthmatic population may be sensitive to aspirin and other NSAIDs.

Definition
20%
Term

Can GERD lead to asthma symptoms? What does GERD stand for?

Definition
Yes; Gastroesophageal reflux
Term

Patients with asthma often have more difficulty during what times of the day?

Definition
Late night or early morning
Term
Can there be a psychological component?
Definition
Yes
Term

Manifestations of asthma may worsen in females ___ before menstruation begins.

Definition
2-3 days
Term

How is asthma diagnosed in children? Adults?

Definition
Based primarily on the assessment of the child’s symptoms and physical findings-and good clinical judgement. A complete hx and physical examination-along w/demonstration of reversible and variable airflow obstruction
Term

Why is occupational asthma often missed in diagnosis?

Definition
 B/c it usually has a slow and insidious onset
Term

List the GINA guidelines to help in the clinical diagnosis of asthma?

Definition
There are many signs and symptoms that should increase the suspicion of asthma. This includes wheezing and a hx of any of the following: cough, recurrent wheeze, recurrent difficult breathing, recurrent chest tightness
Term

The 4 common tests used for diagnosis and monitoring of asthma include:

Definition
spirometry, PEF, measurements of airway responsiveness and the presence of allergies.
Term

What are the 4 categories of symptoms described by GINA?

Definition

-Intermittent-occur less than once a wk and possible brief exacerbations. Also may include nocturnal symptoms not more than twice a mo

-Mild persistent-symptoms occur more than once a week, but less than once a day and exacerbations may affect activity and sleep. Nocturnal symptoms also occur twice a mo

-Moderate persistent-symptoms occur daily and exacerbations effect activity and sleep. Nocturnal symptoms occur more than once a week and individual uses an inhaled short acting beta2 agonist

-Severe persistent-symptoms occur daily along with frequent nocturnal symptoms, there are also limitations on physical activity

Term

Recognize chest assessment findings.

Definition
Expiratory prolongation, decreased tactile and vocal fremitus, hyperresonant percussion note, diminished breath sounds, diminished heart sounds, wheezing and rhonchi
Term

What are the 5 major components of asthma care described by GINA?

Definition

Component 1: Develop Patient/Doctor Partnership

Component 2: Identify and reduce exposure to risk factors

Component 3: Assess, treat, and monitor asthma

Component 4: Manage asthma exacerbations

Component 5: Special considerations in managing asthma

Term

Define asthma exacerbation.

Definition
Also called an asthma attack, or asthma episode. A progressive increase in shortness of breath, cough, wheezing, or chest tightness or a combination of these symptoms.
Term

Can asthma exacerbations be life threatening?

Definition
Yes
Term

What are special considerations to take into account when managing asthma?

Definition
Pregnancy, surgery, rhinitis, sinusitism, and nasal polyps, occupational asthma, respiratory infection, gastroesophageal reflux, aspirin-induced asthma, anaphalaxis
Term

What respiratory care treatment protocols are used with Asthma?

Definition
O2 therapy, bronchopulmonary hygiene therapy, aerosolized medication, mechanical ventilation
Term

Define status asthmaticus.

Definition
 A severe asthmatic episode that does not respond to conventional pharmacologic therapy.
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