Term
| What are the three bronchodilator drugs? |
|
Definition
Methylxanthines
Anticholinergics
Beta2 Agonists |
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Term
| What are the Anti inflammatory drugs? |
|
Definition
IgE Blockers
Cromolyn
Leukotriene Modifiers
Glucocorticoids |
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Term
| What is the preferred method of delivery and why? |
|
Definition
| inhalation pros-rapid onset of action, less systemic effects and because oral drugs are subject to first pass effect. |
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Term
| With MDI's only about ___% of the drug reaches the lungs. |
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Definition
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Term
| With DPI's only about ____% reaches the lungs |
|
Definition
|
|
Term
| Use of a spacer with a MDI increases the amount of medication that reaches the lung to ___%. |
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Definition
|
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Term
| What are the major SE of Beta2-adrenergic agonists? |
|
Definition
| tachycardia, angina, tremor |
|
|
Term
| What is the peak for Albuterol effects? how long lasting? |
|
Definition
| effects almost immedeately (take 5' before exercise) and peak at 30-60 min, lasts for 3-5 hrs |
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Term
| What is the peak for Salmeterol? How long does it last? SE? |
|
Definition
| Slower onset for long acting inhaled B2A's, persist for 12 hrs, great for at night, onset 10-30'. SE-Tachyphylaxis (sudden resistance to the drug) |
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|
Term
| What are the pros/cons of oral steroids for anti inflammatory? SE? |
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Definition
| More side effects esp: tremor, can cause tachycardia, angina, dysrhythmias |
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|
Term
| Anticholinergics have an _____ effect when used with B2agonists and can be inhaled in MDI/DPI. |
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Definition
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Term
| SE from anticholinergics include: |
|
Definition
|
|
Term
| What two conditions are anticholinergics indicated for? |
|
Definition
|
|
Term
| What is the MOA of Methylxanthines? |
|
Definition
| Relax smooth muscle causing bronchodilation, also stimulates CNS, cardiac excitation, vasodilation and diuresis |
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|
Term
| What is a common methyxanthine? |
|
Definition
|
|
Term
| What is a common methyxanthine? |
|
Definition
|
|
Term
| What are adverse SE of chronic steroid use? |
|
Definition
| Adrenal supression, osteoporosis, bruising, edema, peptic ulcer disease, hyperglycemia, growth supression in kids |
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Term
| Guidlines for Mild Intermittent Asthma: |
|
Definition
|
|
Term
| Guidelines for Mild Persistent Asthma: |
|
Definition
| +Low Dose inhaled steroids |
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|
Term
| Guidelines for Mod Persistent Asthma: |
|
Definition
| Low to medium dose inhaled steroids, LA inhaled B2a |
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|
Term
| Guidelines for Severe Persistent Asthma: |
|
Definition
| High dose inhaled steroids, LA inhaled B2a, oral steroids PRN |
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|
Term
| Guidelines for ACUTE Exacerbation of Asthma: |
|
Definition
| Ih B2a, IV/Oral Steroid, Supplemental O2 >95%, SQ epi, Hx |
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|
Term
| For COPD anticholinergics are ___ effective and steroids ___ effective than with asthma |
|
Definition
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