Term
| short acting beta2 agonists (SABA) (5) |
|
Definition
| albuterol, terbutaline, metaproterenol, pirbuterol, levalbuterol |
|
|
Term
|
Definition
|
|
Term
| SABA administered as an autoinhaler MDI |
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Definition
|
|
Term
| onset of action: 2-3min; duration: 4-6h |
|
Definition
|
|
Term
| tx for status asthmaticus |
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Definition
|
|
Term
|
Definition
|
|
Term
| long acting beta2 agonists (LABA) (2) |
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Definition
|
|
Term
| of salmeterol and fometerol, which one has a more rapid onset of action? |
|
Definition
|
|
Term
| nonselective beta agonist |
|
Definition
|
|
Term
| MOA: inhibits adenosine, Ca++ release, PDE |
|
Definition
|
|
Term
|
Definition
| theophylline, aminophylline |
|
|
Term
| administration routes of theophylline vs. aminophylline |
|
Definition
| theophylline-oral; aminophylline-IV |
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|
Term
| indicated for COPD; inhibits late phase response |
|
Definition
|
|
Term
| AE: seizures and arrhythmias at therapeutic doses |
|
Definition
|
|
Term
|
Definition
| ipratroprium, tiotroprium |
|
|
Term
| pharmacology of ipratroprium vs. tiotroprium |
|
Definition
| ipratroprium: 20-30min onset; 4-6h duration // tiotroprium: slower onset, longer duration, 1x/day, DPI |
|
|
Term
| indicated for COPD; can be dosed once a day as a DPI |
|
Definition
|
|
Term
| 2 "asthma" drugs that are not yet indicated for asthma but approved for COPD |
|
Definition
| methylxanthines, tiotroprium |
|
|
Term
|
Definition
| inhibits early and late responses, increases expression of beta receptors; inhibits macrophage and eosinophil release of mediators |
|
|
Term
| administered as a nebulizer; indicated for children and elderly |
|
Definition
|
|
Term
| corticosteroid administered as a DPI and MDI |
|
Definition
|
|
Term
| corticosteroid that is good for children because of its small doses |
|
Definition
|
|
Term
| AE at high doses: oropharyngeal candidiasis, dysphonia, ocular cataracts, growth rate changes |
|
Definition
| non-systemic corticosteroids |
|
|
Term
| used to shorten duration and severity of an acute asthma exacerbation |
|
Definition
| systemic steroids (oral or IV) |
|
|
Term
| MOA: affects Cl- channels; inhibits mast cell release of mediators and early response |
|
Definition
|
|
Term
| MOA: inhibits neuronal reflex to irritants, exercise, and cold; inhibits late response |
|
Definition
|
|
Term
| indicated for exercise-induced asthma |
|
Definition
| sodium cromolyn, nedocromil |
|
|
Term
| MOA: LD4 receptor antagonist |
|
Definition
|
|
Term
| MOA: inhibits 5-lipoxygenase |
|
Definition
|
|
Term
| AE of leukotriene reducers |
|
Definition
| inhibits P450 enzyme -> many drug interactions |
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|
Term
| indicated for pts with high IgE levels; pts with peanut allergies |
|
Definition
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