Term
| majority of toxicities occurs where? |
|
Definition
|
|
Term
| most poisonings are cuased by 1 or more than 1 drug |
|
Definition
|
|
Term
| what are teh 2 mian medicaiton error |
|
Definition
accidently took med twice
wrong med was taken |
|
|
Term
|
Definition
|
|
Term
| some sypmtoms of a toxic patient?-3 |
|
Definition
hypotension
altered mental status(AMS)
GI |
|
|
Term
| Treatment for a toxic patient acronym-2 |
|
Definition
|
|
Term
|
Definition
A- airway
b-breathing
c-circulation
d- decontam
e-elimination
f-focused therapy
g0 get help |
|
|
Term
acronym for bradycardia?
meaning? |
|
Definition
PACED
P-propanol
A-antiarrythmics
c-clonidine
E-eTOH
D-digoxin |
|
|
Term
acronym for tachycardia?
meaning? |
|
Definition
FAST
F-free cocaine
a- antihistamine
s-sympathomiimetc
t-theophylline |
|
|
Term
acronym for hypothermia
meanings |
|
Definition
COOLS
carbon monoxide
opioids
oral insulin
liquor
sedatives |
|
|
Term
acronym for hyperthermia
meaning |
|
Definition
NASA
n-nicotine
a-AWDS - alcohol withdrawal
s-salicylates
a-anticholinergics |
|
|
Term
|
Definition
CRASH
c-clinidne
r-rodenticides
a-antihypertens
s-sedative
h-heroin |
|
|
Term
|
Definition
CTSCAN
c-cocaine
t-thyoid
s-sympathomimetc
c-caffeine
a-amphetamine
n-nicotine |
|
|
Term
acronym for toxicites causing coma
wht ones to know?-5 |
|
Definition
LETHARGIC
ethanol, glycol, TCA, rohypnol, cyanide |
|
|
Term
acronym for what cuases seizures (4 letters)
what need to know-2 |
|
Definition
OTIS
sympathomimetics, salicylates |
|
|
Term
acronym for what cuases seizures (more than 4 letters)
what need to know? |
|
Definition
CAMPBELL
propanolol, BDZ/ethanol withdrawl, ehtylene glycol |
|
|
Term
| which med most assoc with seizures? |
|
Definition
|
|
Term
equation for anion gap:
normal range |
|
Definition
|
|
Term
| elevated anion gap ancronym and meds |
|
Definition
MUDPILES
m-metofrmin
u-uremia
d-DKA
p-propopfol
i-iron/ibuprofen
l-lactate
e-etoh
s-salicylates |
|
|
Term
equation for osmolal gap
1)
2)
wha is normal range? |
|
Definition
1)2Na + glc/18 + BUN/2.8 OH/correction factor
2)measured-calculated
-14-10 |
|
|
Term
| acronym for elevated osmolal gap |
|
Definition
MEDIE
M-methanol
e-ehtylene glycol
d-diuretics
i-isoproyl
e-ethanol |
|
|
Term
|
Definition
cost
lack of cut-offs
false tests |
|
|
Term
|
Definition
urine drug screen
serum blood |
|
|
Term
| serum conc of these drugs may be useful for managment-3 |
|
Definition
| APA, saliclyate, alcohols |
|
|
Term
| if unknown what pt ingested alwys run what test |
|
Definition
|
|
Term
| qualitative drug screening should be when |
|
Definition
|
|
Term
| quantitavte dru screens (blood) should be done when? |
|
Definition
| for drugs that guide therapy like in other flashcard |
|
|
Term
| toxidrome for cholinergics |
|
Definition
DUMBELLS
d-duarrhea
u-urination
m-miosis
b-bradycardia
e-emeisis
l-lacrimation
l-lethargy
s-salivation |
|
|
Term
| low dose anticholinergic= |
|
Definition
|
|
Term
| medium dose of anticholinergic=-2 |
|
Definition
|
|
Term
| high dose of anticholinergics cause-2 |
|
Definition
|
|
Term
| toxidrome symtpoms of anticholinergics-4 |
|
Definition
|
|
Term
| toxidrome for smypathomimetics-3 |
|
Definition
| hyperthermia, tachycardia, seizures |
|
|
Term
| opiod toxidrome symtpoms-3 |
|
Definition
miosis
bradycardia
hypotension |
|
|
Term
|
Definition
CNS depression
resp depression
hypothermia |
|
|
Term
| sedative withdrawal may appear like what toxidrome? |
|
Definition
| sympathomimetic (can die formt his) |
|
|
Term
| opioid withdrawal symptoms-2 |
|
Definition
|
|
Term
| look at slide 30 right before test for quick toxidorme review |
|
Definition
|
|
Term
|
Definition
| prevetn reabsorption of subtance after its ingested |
|
|
Term
|
Definition
emesis
acitavted charcoal
gastric lavage |
|
|
Term
what induces emeiss
the thing to note: |
|
Definition
syrup of ipecac
no longer reccomedned |
|
|
Term
| is gastric lavage indicated for most meds? |
|
Definition
|
|
Term
|
Definition
| surface area for adsorption of toxins |
|
|
Term
dose of activated charcoal-
most effective if given how mnay hrs after ingestion |
|
Definition
|
|
Term
mult dose acitvated charcoal (MDAC):
dose:
don';t give with |
|
Definition
25 gm q 2 hrs
cathartics like sorbitol |
|
|
Term
|
Definition
|
|
Term
| susbtances adsrobed by MDAC-4 |
|
Definition
ABCD
A-aspriin/theophylline, antimalarial, barbs, carbamez, dapsone |
|
|
Term
| 3 things not adsorbed by AC |
|
Definition
| lithium, alcohol, potassium |
|
|
Term
| AC is contraindicated when? |
|
Definition
| ariway reflexes protected or not intact |
|
|
Term
| sorbitol can be given as sweetner with only? |
|
Definition
|
|
Term
whole bowel irrigaiton dose:
when to use?-3 |
|
Definition
1 L/hr
lithium, ER/SR agents, others not adsroed by charcoal |
|
|
Term
| what is the step of tox managment AFTER drug has been absrobed? |
|
Definition
|
|
Term
| how do you enhance eliminaiton-2 |
|
Definition
alkinilization
hemodialysis |
|
|
Term
| look thruout lect for the quesiotn sldies |
|
Definition
|
|
Term
| CCB/BBs toxiciity symtpoms-3 |
|
Definition
| bradycardia ,conduction block, myocardium depression |
|
|
Term
| what is first line therapy for BB/CCB overdose and dosing ofr it |
|
Definition
|
|
Term
|
Definition
|
|
Term
what are 2 toher therapies for CCB/BB overdose ?
when do you use the 3rd line? |
|
Definition
glucagon 3 mg
HIET (regular insulin) 1 unit/kg
do HIET as soon as other 2 dont work bc delayed onset |
|
|
Term
what are the toxic alcohols-2
which causes eyesight changes? renal falirure? |
|
Definition
methanol
ehtlyene glycol;
methanol; glycol |
|
|
Term
treatments and dosing for toxic alcohol over dose-2
which has ease of admin and lasck of aDEs? |
|
Definition
alcohol 100 mg
fomepizole 15 mg/kg;
fomepizole |
|
|
Term
biggest cyanide toxic cause?
signs?-2 |
|
Definition
nitroprusside
lactate >8, tachycadia |
|
|
Term
treatment for cyanide toxicity? -2
which can be given in all siutaitons |
|
Definition
1 amp of amyl nitrate
Nathiosulfate 12.5 gm IV
Nathiosulfate |
|
|
Term
| VitB12a can be givne for what toxicity but needs speerate line? |
|
Definition
|
|
Term
| if deciding to use antidote for BDZ overdose need to consider-2 |
|
Definition
pecipitation fo withdrwala
removal of protective effects of BDZ |
|
|
Term
| treatment and dose for BDZ overdose |
|
Definition
| flumazenil .2 mg IV max of 3 mg |
|
|
Term
|
Definition
| nalaxone 0.04 mg IV then double every min. max of 10 mg |
|
|
Term
| acute tox of digoxin symtpoms?-3 |
|
Definition
|
|
Term
| chronic tox of digoxin symtpms-3 |
|
Definition
GI symtpms
neurospychiatric
visual |
|
|
Term
| how mnay vials for chronic overdose of dignoxin of fab anti0digoxin antibodies |
|
Definition
|
|
Term
| how many vials for acute digoxin overdose of the fab fragments |
|
Definition
|
|
Term
|
Definition
|
|
Term
| typical presentaiton of APAP toxicity? |
|
Definition
|
|
Term
what is the med for APAP overdose?
what does it replenish? |
|
Definition
n-acytlcysteine
glutathione |
|
|
Term
what is IV dosing over 1 hr for APAP overdose
what is PO? |
|
Definition
|
|
Term
| N-acytl cystine reccomedned also if-3 |
|
Definition
APAP level not avail in 8 hrs
repeated ingestion and APA>20
unknown time of ingestion and measurable APAP |
|
|
Term
| the triad of symtpoms fo salicylte overdose |
|
Definition
hyperventilation
tinnitis
GI irritaiton |
|
|
Term
| treatment for salicylate overdose-2 |
|
Definition
MDAC 25 mg q2hrs
fluid resusications |
|
|
Term
| use hemodialysis for salicylate overdose-3 |
|
Definition
apsirin>100
acidosis
renal failure |
|
|
Term
| glycemic toxicity from antidiabetics is when BG< |
|
Definition
|
|
Term
| what do you use for hypoglecmia? |
|
Definition
|
|
Term
| if pt symtpomatic or BG <60, what do you use? |
|
Definition
|
|
Term
| if pt needs a lot of rescue dextrose doses for hypoglycemia, consider using? |
|
Definition
|
|
Term
|
Definition
| hypotension, arrythmia, anticholinergic, CNS |
|
|
Term
| 1st line for TCA toxicity? |
|
Definition
|
|
Term
| for cardiac instability with TCA toxicity, stpes for treatment-4 |
|
Definition
IV fluids
NaHCO3 1 meQ/kg
Ne if still hypotensive
glucagon 10 mg for slavage |
|
|
Term
for prevention of seizures with TCA toxicity use?
avoid? |
|
Definition
|
|
Term
| if TCA toxicity is refractros use |
|
Definition
| IV fat emulsion (is a lipid sink, the drugs will get held in fat) |
|
|
Term
| what is dosing for IV fat emulsion |
|
Definition
20% IVFE 100 mL over 1 min
then .25 ml/kg/min following bolus |
|
|
Term
| what is max dose for IV fat emulsion? |
|
Definition
|
|
Term
| wtihdrawal of opioid treatment? -2 |
|
Definition
slow taper of long acting opiod
symtpoms control like anteemtic, clonidine |
|
|
Term
| drugs not adsrobed by AC acronym and meaning |
|
Definition
LIPSHA
L- lithium
I-iron
P-potassium
S-solvents
H- hydrocarbons
A-alcohol |
|
|
Term
| how is whole bowel irrigaiton admin? |
|
Definition
|
|
