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Asepsis & Infection
Fundamentals Ch. 34
16
Nursing
Undergraduate 1
11/27/2010

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Term
Penicillin
Definition
1. Inhibits cell wall synthesis.
2. Kills bacteria= Bactericidal.
3. Broad-Spectrum.
* Side Effects: N/V/D; Anxiety; Abd Pain; Allergic Reactions; Less Common Convulsions.
Term
Cephalosporin
Definition
1. Inhibits cell wall synthesis.
2. Kills bacteria= Bactericidal.
3. Broad-Spectrum.
* Side Effects: Anorexia; N/V/D; Rash; Abd Cramps; Fever; Pruritus; HA; Vertigo; Weakness.
Term
Cefixime (Suprax)
Definition
1. Only oral 3rd. Generation.
2. Suprax has structural changes to allow for better oral absorption.
Term
Quinolones
Definition
1. Kills bacteria-Bactericidal.
2. Antacids decrease absorption.
3. Used 4 tx of UTI.
*Side Effects: HA; Dizziness; Fatigue; Depression; Restlessness; N/V/D; Constipation; Rash; Puritis; Photosensitivity; Flushing; Fever; Chills; Blurred Vision.
Term
Azithromycin
Classification: Macrolides
Definition
Frequently used 4 pt allergic to penicillin.
Term
Classification: Macrolides
Meds: Erythromycin; Azithromycin; & Clarithromycin
Definition
1. Inhibit growth of bacteria= Bacteriostatic.
2. Tx Strep; Mild-Moderate UTI; Syphilis; Lyme's; Gonorrhea; Chalmydia
Term
Macrolides
Definition
Side Effects: N/V/D; Hepatotoxicity; Jaundice; Anorexia.
Term
Tetracycline
Definition
1. Decrease effectiveness of BC.
2. Decrease oral absorption by dairy products; antacids; and iron salts.
3. Stops new bacterial growth.
4. Avoid tetracycline 4 children under 8; prego & nursing mothers (May cause discoloration of teeth.
Term
Aminoglycosides
Definition
1. Serious Nephro Toxicities.
2. Renal failure can occur c increased peaks.
3. Ototoxicity c increased troughs (effects 8th cranial).
4. Check blood level often
Used for severe infections only.
Term
Sulfonamides
Definition
1. Inhibits bacterial growth.
2. Prevents synthesis of folic acid.
3. Can cause kidney stones.
4. Human cells not effecte; used performed folic acid.
Term
Amphotericin B (Fungazone)
Definition
1. Highly toxic; binds to tissue rather than blood; increased tissue damage.
*Side Effects: renal damage; fever; HA; N/V; anemia; F&E balance; Nephrotoxicity; Hypokalemia
*Used for serious fungal infections.
Term
Azole
Definition
1. Do not give w/in 2 hrs of antacids = hepatotoxicity.
2. Used 4 athletes foot
*Side Effects: N/V/D; dizziness; nervousness; HA; rash; puritis; thrombocytopenia; allergic reaction; CNS effects.
Term
Fluorinated Pyrimidine
Definition
Side Effects: N/V/D; anemia; thrombocytopenia; hepatotoxicity; bruising.
Term
Antivirals
Definition
1. Inhibit viral reproduction.
2. Protection is immediate.
3. Dosage must be accurate.
Term
"Avirs"
Indinavir (Crixivan); Ritonavir (Norvir); Squinavir (Invirase)
Definition
Protease Inhibitors.
Side Effects: Kidney stones; abd pain; N/V/D; HA; Weakness; and altered taste.
Term
Sites for HAI infections
Definition
Urinary Tract; Surgical or Traumatic Wounds; Respiratory Tract; Bloodstream
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