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composed of myosin molecules thicker one in each layer (in the middle) |
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formed by the joined ends of thin filaments zig-zag line |
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composed of actin, troponin, and tropomyosin thinner 2 of each in a layer |
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a small globular protein each thin filament contains wo strands of this molecule that are twisted together each molecule contains a binding site for a myosin head on a thick filament |
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thick filaments are bundles of this each molecule is composed of a long shaft, one end of which terminates in two globular heads (like a golf club) each myosin head has two important binding sites, one for ATP and one for thin filaments |
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1. myosin binding sites on the actin molecules are covered in resting fibers 2. the action potential increases Ca2+ from the SR 3. Ca2+ binds troponin. Tropomyosin moves, revealing myosin binding sites 4. cross-bridge forms when myosin head binds actin 5. Power stroke= myosin head pivots moving actin. ADP and P dissociate from the myosin head 6. Myosin head releases actin when a fresh ATP binds 7. Mysoin head binds next actin. The ATP is cleaved to ADP + P; the cycle repeats |
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