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Applied Exercise Physiology Exam 3
University of Iowa
288
Physiology
Undergraduate 4
10/24/2018

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Cards

Term
What are the functions of the respiratory system?
Definition
- gas exchange
- regulation of pH of extracellular fluid
- smell receptors
- filters air
- eliminates heat and excess water
Term
What is the most important respiratory system function?
Definition
removing CO2
Term
What does formed CO2 do when bound with H2O?
Definition
create an acid (this is a threat to our pH)
Term
Respiration
Definition
the overall process of controlled oxidation of metabolites for the production of useful energy
Term
What does respiration consist of?
Definition
- pulmonary ventilation
- external respiration
- internal respiration
- cellular respiration
Term
Pulmonary Ventilation (VsubE)
Definition
movement of air in and out of the lungs
Term
External Respiration
Definition
- happens at the alveolar level
- this is the gas exchange between venous blood and the air in the alveoli
Term
Internal Respiration
Definition
gas exchange between blood and peripheral tissues
Term
Cellular Respiration
Definition
- occurs inside of tissues
- allows cells to do cell things
Term
Is the respiratory system a closed system or open system?
Definition
open
Term
What is the respiratory system composed of?
Definition
- nose
- pharynx
- larynx
- trachea
- bronchi
- lungs
Term
What are the two structural divisions of the respiratory system?
Definition
- upper
- lower
Term
What does the upper respiratory system consist of?
Definition
- nose
- pharynx
Term
What does the lower respiratory system consist of?
Definition
- larynx
- trachea
- bronchi
- lungs
Term
What is the conduction portion of the respiratory system?
Definition
a series of tubes that help bring air to the lungs
Term
What are the four main functions of the conduction portion of the respiratory system?
Definition
- filter air that enters
- warm the air
- moisturize the air
- conduct if from point A to B
Term
In the conduction portion of the respiratory system, what is point A and what is point B?
Definition
point A: ambient environment
point B: terminal respiratory units
Term
What are the two portions of the conduction tubes?
Definition
- extrapulmonary
- intrapulmonary
Term
Extrapulmonary
Definition
outside of the lungs
Term
Intrapulmonary
Definition
inside of the lungs
Term
What is the structure of the primary bronchus?
Definition
- two branches off of the trachea (R & L)
- incomplete cartilaginous rings
- between rings there is pseudostratified epithelium that is ciliated
Term
What is the structure of the terminal branches of the bronchus?
Definition
- cuboidal epithelium that is un-ciliated
- less pronounced cartilage in plate form
- more smooth muscle
Term
What are the resistance muscles in the respiratory system?
Definition
the bronchioles
Term
What do the bronchioles control?
Definition
the shape of the tubes (this controls air flow and what branches get ventilated)
Term
What does respiratory system sympathetic control look like?
Definition
- bronchodilation
- more concentrated beta receptors
- catecholemines (NT)
Term
What does respiratory system parasympathetic conrol look like?
Definition
- bronchoconstriction
- alpha receptors
- ACh (NT)
Term
What makes up a final bronchiole segment?
Definition
lobule (about 10 total in each lung)
Term
What are the four structures in each final bronchiole segment?
Definition
- lymphatic vessel
- arteriole
- venule
- branch of a terminal bronchiole
Term
What is the terminal bronchiole branch?
Definition
respiratry bronchiole which is part of the terminal respiratory unit
Term
What is the cascade of the respiratory bronchiole?
Definition
alveolar ducts --> alveolus and sacs
Term
What is the alveolus and what is its function?
Definition
- cup shaped out-pouching
- lined by thin squamous epithelium
- supported by thin, elastic basement membrane
- functions in keeping optimal conditions for gas exchange in the lungs
Term
Type I Alveolar
Definition
- dominant
- ideal surface area for gas exchange
- simple squamous epithelium
Term
Type II Alveolar
Definition
- septal, cuboidal cells
- micro-villi
- intermittent
- secrete alveolar fluid (contains surfactant)
Term
Surfactant
Definition
detergent like compound that will decrease the surface tension in the lungs (keeps alveoli from collapsing)
Term
Dust Cells
Definition
- alveolar macrophages
- keep exchange area clean (what we miss with air filtration)
- can be overwhelmed
Term
How much do the lungs weigh?
Definition
800-1200 grams
Term
How much of the weight of the lungs is blood?
Definition
40%
Term
What is atmospheric pressure?
Definition
760 mmHg
Term
What nerve initiates breathing?
Definition
phrenic nerve
Term
What needs to be done in order for us to actively inspirate?
Definition
we need to add work
Term
What muscle allows us to actively inspirate?
Definition
diaphragm
accessory muscles are the intercostals
Term
At what level is inspiration initiated?
Definition
brain stem (pons and medulla)
Term
What are the two mechanisms of lung expansion?
Definition
diaphragm and external
Term
What happens when the diaphragm contracts?
Definition
it pushes the abdominal contents down and extends the length of the thoracic cavity
Term
While inspiration is active, expiration is ________.
Definition
passive
Term
What happens to expiration when we exercise?
Definition
it becomes active
Term
If the diaphragm and rib cage cannot allow maximum gas exchange during exercise, what will we utilize?
Definition
the internal intercostals and the abdominal muscles
Term
What neck muscles are recruited during forced expiration?
Definition
sternocleidomastoid and scalenes
Term
What is the intrapulmonic and intrapleural pressure at rest?
Definition
760 mmHg
756 mmHg
Term
What is the intrapulmonic and intrapleural pressure during inspiration?
Definition
758 mmHg
754 mmHg
Term
What is the intrapulmonic and intrapleural pressure during expiration?
Definition
763 mmHg
756 mmHg
Term
What are the two types of transpulmonary pressure?
Definition
pleural and intrapulmonic/alveolar pressure
Term
During expiration, the lungs are moving ________.
Definition
passively
Term
Pleural pressure
Definition
pressure between the two layers of the membranes of the lugs and rib cage
Term
Intrapulmonic/alveolar pressure
Definition
pressure inside of the lungs
Term
How much energy are we investing in breathing during rest vs exercise?
Definition
3-5% at rest, about 50x that with exercise
Term
Hyperpnea
Definition
an increase in the rate/depth of breathing
Term
Total Lung Capacity
Definition
- just over 7 L
- don't utilize it all
Term
Vital Capacity
Definition
- volume between maximal inspiration and maximal expiration
Term
Title Volume
Definition
- normal resting breath
- difference between inspiration and expiration
- typically 5 L
Term
Functional Residual Capacity
Definition
- residual volume after maximal exhalation
- more at rest than during exercise
Term
Residual Volume
Definition
- leftover air in lungs
- we cannot fully fill or drain lungs
Term
Frequency
Definition
breaths per minute (12)
Term
Minute Ventilation
Definition
tidal volume * frequency
Term
Capacity
Definition
sum of two or more volumes
Term
Ventilation/Perfusion Ratio
Definition
ventilation/cardiac output
Term
What does/ the ventilation/perfusion ratio represent
Definition
the efficiency of exchange of gas
Term
If there is a major change in flow, how long will it take for it to even out between sides?
Definition
2-3 heartbeats
Term
Systole difference between left and right ventricles?
Definition
120 vs 25
Term
Why is the pressure in the right ventricle so low?
Definition
because pulmonary circulation is a LOW PRESSURE SYSTEM
Term
What are the three factors that allow pulmonary circulation to be low pressure?
Definition
- large number of someone muscular arteries
- large pulmonic capillary beds
- low vascular tone
Term
What is the worst thing that can happen in pulmonary ventilation?
Definition
right sided hypertension (narrowing of vessels, requires heart transplant)
Term
At rest, how much of our body's blood is in the pulmonary system?
Definition
about 10%
Term
What is wasted ventilation?
Definition
blood that does not go through gas exchange
Term
What provides the most ideal conditions for gas diffusion in the body?
Definition
the respiratory membrane
Term
How does the blood flow around the alveolus?
Definition
in a sheet
Term
What are the four layers of the respiratory membrane?
Definition
- alveolar wall
- basement membrane of alveolus
- (interstitial space)
- basement membrane of capillary
- capillary wall
Term
What are the two components for optimal diffusion of O2 and CO2?
Definition
- large surface area
- short diffusible distance
Term
How long will blood typically spend in the capillaries at one time?
Definition
3/4 of a second
Term
What happens when we exercise to the respiratory membrane?
Definition
we cannot increase the distance of diffusion, but can increase the surface area
Term
Partial pressure
Definition
the pressure exerted by a gas as if it were the only molecule present
Term
Dalton's Law
Definition
the sum of partial pressures
Term
What does 760 mmHg equal in atm's?
Definition
1
Term
What are the gases and their percentages that make up ambient air?
Definition
- N (79%)
- O (20.93-21%
- CO2 (.03%)
Term
When we increase in altitude, what happens to the pressure of the air?
Definition
it is lower
Term
What happens to air when we breathe it in?
Definition
the partial pressure changes because the air warms up and moistens
Term
Where does venous blood travel and what determines its speed?
Definition
- from capillary beds to heart
- directly proportional to the width of the gradient
Term
The solubility of gas into fluid is ________ at a constant temperature.
Definition
constant
Term
What are the byproducts of gas exchange?
Definition
- H2O
- CO2
- heat
- free energy
Term
What ratios are altered during gas exchange?
Definition
NAD/NADH and FAD/FADH
Term
Alveolar ventilation
Definition
amount of air that gets to the alveoli
Term
Physiological dead space
Definition
150 mL of air that does not participate in gas exchange or go to the alveoli
Term
Ventilation/perfusion ratio
Definition
how well we can match our breathing to our blood flow to the alveolar capillaries
Term
What is the purpose of breathing?
Definition
to maintain the composition of the alveolar gas
Term
Fick's Law
Definition
The net diffusion rate of a gas across a fluid membrane is proportional to the difference in partial pressure, proportional to the area of the membrane and inversely proportional to the thickness of the membrane.
Term
What are the three things that the rate of diffusion is directly proportional to?
Definition
- diffusible surface area
- width of the gradient
- diffusion constant of the gas
Term
What is the thing that the rate of diffusion is indirectly proportional to?
Definition
the diffusible ditance/thickness of the membrane
Term
Which is greater, the diffusion constant for CO2 or O2?
Definition
CO2
Term
What happens to the gradient for exchange with exercise?
Definition
it increases
Term
What happens to the partial pressure of oxygen with exercise?
Definition
it decreases
Term
What happens to cardiac output with exercise?
Definition
it increases
Term
Why does cardiac output increase with exercise?
Definition
- increased diffusible surface area
- low diffusible distance
Term
Without ________, we would be limited because O2 does not dissolve well in H2O.
Definition
hemoglobin
Term
What is hemoglobin and what does it do?
Definition
It is the primary protein of red blood cells and it allows us to carry O2 70X more efficiently than without it.
Term
What is the oxygen saturation percentage?
Definition
ratio of oxygen bound to hemoglobin:amount that has the potential to be bound
Term
Is the binding of oxygen to hemoglobin reversible?
Definition
yes
Term
If there is a higher concentration of O2, what is favored?
Definition
binding with hemoglobin
Term
What is the oxyhemoglobin dissociation curve affected by?
Definition
pH and temperature
Term
What are the three methods of CO2 transportation in the blood?
Definition
Bicarbonate (60-70%)
Dissolved (7-10%)
Carbaminohemoglobin
Term
What is the bicarbonate mechanism of CO2 transportation?
Definition
- carbonic anhydrase (RBC enzyme)
- chloride shift
- process reverses itself at the lungs
Term
Which gradient, O2 or CO2, is wider and takes longer at the level of the alveolus?
Definition
O2
Term
During exercise the gradient ______.
Definition
widens
Term
Transport of O2 is effected by the amount of ____ it has to go through
Definition
water
Term
It is more important to get O2 into the ______ than the ________.
Definition
cell, mitochondria
Term
Why must O2 exchange happen fairly rapidly?
Definition
because it has limited time in the capillaries at the level of the muscles
Term
Having a thicker membrane will ______ the time it takes and _____ diffusion.
Definition
increase, limit
Term
At rest the mL of oxygen in 100 mL of blood in the arteries is _____ and in the veins it is ______.
Definition
20, 15-16
Term
During exercisethe mL of oxygen in 100 mL of blood in the arteries is _____ and in the veins it is ______.
Definition
20, 5
Term
Absolute terms
Definition
mL of oxygen in 100 mL of blood
Term
What has a higher affinity for oxygen, myoglobin or hemoglobin?
Definition
myoglobin
Term
What happens to oxygen during exercise in relation to myoglobin and hemoglobin?
Definition
myoglobin will pull oxygen away from hemoglobin
Term
P_a vs P_A
Definition
P_a is the arterial side, P_A is the alveolar side
Term
What drives breathing?
Definition
P_aCO2
Term
When CO2 is in equilbrium, the pressure in the arterial side is _____ to the alveolar side,
Definition
equal
Term
If pressure drops below 60 mmHg, what will happen to CO2?
Definition
it can be overridden by an O2 controller
Term
If the O2 controller overrides CO2, what will happen?
Definition
we will breathe more and increase the partial pressure of the alveolar gas
Term
What are the two separate, but overlapping, patterns of respiratory control?
Definition
metabolic ad behavioral
Term
Metabolic control
Definition
involuntary drive to breathe (autonomic)
Term
Behavioral control
Definition
voluntary breathing (somatic and autonomic)
Term
What is the importance of metabolic breathing?
Definition
controls pH
Term
What are the four medullary respiratory centers?
Definition
nucleus tractus solitarius, nucleus retroambiguous, apneustic centerm and pneumotaxix center
Term
Nucleus Tractus Solitarius
Definition
activated primarily by inspiration
Term
Nucleus Retroambiguous
Definition
activated by both inspiration and expiration (diaphragm, intercostals, and abdominal muscles)
Term
Apneustic Center
Definition
causes elongation of the inspiratory process
Term
Pneumotaxix center
Definition
involved between the switch between inspiration and expiration
Term
Which breath is constant and which is phasic/intermittent?
Definition
inspiratory is constant, expiratory are phasic
Term
What are the two types of chemoreceptors of the respiratory system?
Definition
cental and peripheral
Term
Central Chemoreceptors
Definition
of the CNS (brain/spinal cord), primarily responsible for responding to changes in the partial pressure of CO2 (75%)
Term
Peripheral Chemoreceptors
Definition
carotid bodies and aortic arch, responsible for changes in the partial pressure of CO2 (25%) and oxygen
Term
What do chemoreceptors do?
Definition
they send feedback to the breathing control centers and will adjust breating in order to return blood gas levels back to homeostatic levels
Term
Hypercapnia
Definition
- central
- partial pressure of CO2 goes up
Term
Hypoxia
Definition
- peripheral
- partial pressure of O2 drops
- can cause alkaline environment
Term
Asphyxia
Definition
combination of hypercapnia and hypoxia
Term
Mechanoreceptors
Definition
respond to the forces that occur with movement, play a role in the rhythm of breathing
Term
What happens when breathing in?
Definition
water is saturated and displaces oxygen
Term
Endotherm
Definition
"warm blooded", our metabolic hear is our main way of maintaining internal temperature
Term
Homeotherm
Definition
maintenance of a constant core temperature
Term
Regulating organisms
Definition
capable of maintaining constant internal environments regardless of changes in external environments
Term
Core temperature is measured where?
Definition
rectum
Term
Peripheral/shell temperature
Definition
usually skin, will be lower than core temperature
Term
In relation to core temperature, what is the difference between it and metabolically active tissue?
Definition
metabolically active tissue can have a higher temperature
Term
Ambient temperature
Definition
conditions of the ambient environment
Term
When muscle temperature goes up during exercise, what must our bodies do?
Definition
change the blood flow pattern to take heat from muscle and bring it to the periphery
Term
What are the two parts of the human thermostat?
Definition
pre-optic anterior hypothalamus and posterior hypothalamus
Term
Pre-optic anterior hypothalamus
Definition
main governor of heat dissipation mechanisms
Term
Posterior hypothalamus
Definition
plays a role in cold environment, governs heat conservation
Term
What are the three components of a negative feedback system?
Definition
sensors, controllers, and effectors
Term
Sensors
Definition
help detect deviations from normality
Term
Controllers
Definition
take sensory info and compare it to our set point and then initiates corrective actions
Term
What is the integrator of the controllers of a negative feedback system?
Definition
the hypothalamus
Term
Effector
Definition
brig about the corrective actions
Term
Specialized nerves/peripheral sensors
Definition
give us information about our skin temperature (influenced by ambient temperature)
Term
Vasomotion
Definition
redirection of blood flow from one location to another
Term
What are the different mechanisms of temperature regulation controllers?
Definition
vasomotion, hormonal activity, sudomotor activity, involuntary & voluntary motor activity, and behavioral adjustments
Term
Hormonal activity
Definition
we activate our sympathetic nervous system (catecholemines) which will influence our metabolic rate
Term
Sudomotor activity
Definition
sweating
Term
Involuntary and voluntary motor activity
Definition
Voluntary: exercise
Involuntary: shivering
Term
Behavioral adjustments
Definition
increasing or decreasing insulation (clothing)
Term
How do we regulate temperature without movement?
Definition
non-shivering thermogenesis
Term
What are examples of structures that are sensors?
Definition
- peripheral sensors in skin
- deep body sensors in the brain
- nerve endings in hypothalamus
Term
What dose the hypothalamus control?
Definition
heat dissipation and conservation
Term
What are examples of effectors in thermoregulation?
Definition
- blood vessels
- muscles
- sweat glands
- thyroid glands
Term
What is a heat soruce?
Definition
something higher in temperature than our bodies
Term
What is a heat sink?
Definition
something that causes heat dissipation
Term
Law of conservation of energy
Definition
for a system to be in balance in all avenue of heat, then gain must equal loss
Term
What is blood's role in thermoregulation?
Definition
it can store a lot of heat and we can shunt it from place to place
Term
Most tissues in the body are ________ conductors of heat.
Definition
poor
Term
Counter-current heat exchange
Definition
core to periphery and then reverse
Term
How do we conserve heat in a colder environment?
Definition
our arterial blood passes heat to our venous blood as they pass each other
Term
Flow in heat transfer
Definition
limited to the muscle, the gradient will be thinner so the blood is hotter
Term
Storage capacity in heat transfer
Definition
heat storage, temperature when it reaches the area
Term
Delta temperature in heat transfer
Definition
gradient, wider gradient = cooler
Term
The gradient and the storage capacity are ________ proportional.
Definition
directly
Term
What is the Nelson formula for?
Definition
the equation for thermal balance and efficiency of heat transfer
Term
Nelson formula equation
Definition
M + (R + K + C) - E + W + S = 0
Term
M
Definition
metabolic rate
Term
R
Definition
radiation
Term
K
Definition
conduction
Term
C
Definition
convection
Term
E
Definition
evaporation
Term
W
Definition
work
Term
S
Definition
storage
Term
Methods of dry heat exchange
Definition
radiation, conduction, convection
Term
Metabolic heat
Definition
- produced
- always positive (heat source)
- the body's way of creating heat
- quantified by kiloCals consumed
Term
What determines kiloCals consumed?
Definition
- oxygen consumption
- respiratory exchange ratio
- caloric cost of this ratio
Term
Radiation
Definition
exchange of electromagnetic waves from one object to another (cannot see the wavelength), can disrupt with clothing, texture, sitting, etc
Term
Why is dry heat exchange different?
Definition
no sweat is used to dissipate heat
Term
What percentage of heat dissipation at rest is radiation?
Definition
65-75%
Term
Conduction
Definition
transfer of heat between two surfaces in direct contact
Term
What percentage of heat dissipation is conduction?
Definition
2-5%
Term
If something accepts heat readily it is a(n) _______, if it resists heat it is a(n) ________.
Definition
conductor, insulator
Term
What is one example of natural insulation, and one example of artificial insulation?
Definition
adipose tissue, clothing
Term
Convention
Definition
heat transfer through a gas or liquid
Term
During convection, will heat transfer faster in water or air?
Definition
water
Term
Things that affect the convective current
Definition
- how much flow
- viscosity
- density
- thermal conductivity
- delta temperature
Term
How much flow
Definition
example: a fan will be different from low to high
Term
Viscosity
Definition
will effect how fast something moves past the skin's surface (no universal effect)
Term
Density
Definition
- directly proportional
Term
Thermal conductivity
Definition
some substances just hold more heat energy
Term
Delta temperature
Definition
the difference between two substances (directly proportional)
Term
Different types of convection
Definition
natural and forced
Term
Natural convection
Definition
hot air rises
Term
Forced convection
Definition
adding some type of energy to achieve this goal
Term
Evaporation
Definition
when water is converted into a gas from liquid form
Term
Latent heat of vaporization
Definition
the amount of heat needed to make sweat evaporate
Term
The effectiveness of evaporation for heat removal from the body is ______ related to how much water on that skin that can be converted to a gas
Definition
directly
Term
What causes the cooling of our bodies?
Definition
the EVAPORATION of sweat
Term
Who is better at sweating?
Definition
women
Term
What are the three types of sweat?
Definition
Insensible, thermal, and non-thermal
Term
Insensible sweat
Definition
amount of fluid on the skin surface that is evaporating at rest
Term
Thermal sweat
Definition
sweat that we put out with the intention of dissipation
Term
Non-thermal sweating
Definition
sweat that occurs due to anxiety or nervousness
Term
Besides sweating, what is another way that we lose water?
Definition
exhalation
Term
In a reference person, how much water do humans lose at rest?
Definition
30 g/hour
Term
During exercise, how much water do we lose per hour?
Definition
1-2 L
Term
What effects the rate of evaporation?
Definition
- humidity
- air movement
- water on the surface of the skin
- latent heat of vaporization
Term
Humidity
Definition
if the air is more saturated with water then we evaporate sweat less efficiently
Term
Air movement
Definition
speed of the movement
Term
Water on the surface of the skin
Definition
too much sweat on the surface will inhibit evaporation efficiency
Term
Variations of latent heat of vaporization
Definition
electrolyte concentration (more dilute sweat evaporates faster)
Term
The Nelson formula in hot and cold environments
Definition
- may be less than 0 in cold environments
- may be more than 0 in hot environments
Term
There are more mechanisms for combating _______ than _______.
Definition
cold, heat
Term
What are mechanisms of cooling in mammals?
Definition
sweating, panting, and vasodilation
Term
During exercise, what is the most dominant form of heat dissipation?
Definition
evaporation
Term
What are the two different classifications of hot environments?
Definition
- hot/dry
- warm/human
Term
Hot/dry environment
Definition
- desert regions
- low overall humidity
- wide variation between day and night temperatures
- ambient air is at a higher temperature than the skin
- will not lose heat by convection, radiation, or conduction
- will only lose heat by evaporation (but it is very effective)
Term
Warm/humid environment
Definition
- tropical rain forest
- not excessive in temperature
- high levels of humidity (up to 75%)
- may not allow evaporation or radiation
- exercise in humidity will be dangerous
Term
What are the four mechanisms of heat loss?
Definition
- vasomotion (dilation of cutaneous vessels)
- store heat in the body
- body size
- sweat
Term
Cutaneous vasodilation
Definition
brings heat from the core to the shell
Term
During cutaneous vasodilation thermal conductance increases _______ fold
Definition
5-6
Term
Sympathetic mediation of skin blood flow
Definition
due to cholinergic activity at the level of the skin, the dual vasomotion mechanism will DILATE the vessels
Term
What is all autonomic reaction regulated at?
Definition
the hypothalamus
Term
Vasodilation mechanisms
Definition
- pressor/depressor center
- change in lumen size to change vessel size
Term
Core to shell concept
Definition
vasomotoin allows us to dissipate heat from the core to the shell
Term
Physiological problems with the core to shell concept
Definition
- finite blood volume
- skeletal muscles during exercise needs a lot of blood, heart works faster
- more vascular beds means lower blood pressure so cardiac output increases
- will lose venous return and stroke volume with dilation
Term
Heat storage
Definition
- related to hydration (dehydration = more heat storage)
- causes core temperature to rise
- heat that we can't dissipate
Term
Thermal inertia
Definition
larger body sizes handle a greater heat load with less of an increase in temperature (smaller objects get hotter in the sun)
Term
When will insensible sweating not occur?
Definition
If there is 100% humidity (not really feasible)
Term
What is the maximal thermal sweat that our bodies can manage?
Definition
4 L/hour (if replacing fluids constantly)
Term
What are the 4 mechanisms for dealing with heat loss?
Definition
- ability to dilate the cutaneous vessels
- ability to store heat in the body
- ability to take advantage of body size
- ability to sweat
Term
What happens during cutaneous vasodilation?
Definition
- core to shell
- thermal conductance increases 5-6 fold
- sympathetic mediation of skin blood flow
Term
What is the goal of vasomotion?
Definition
to increase our cutaneous blood flow
Term
What causes thermal conductance?
Definition
dilation of cutaneous vessels
Term
What does sympathetic mediation do on a heating/cooling level?
Definition
bring the skin temperature closer to the core temperature via vasomotion
Term
What does sympathetic mediation do on a autonomic level?
Definition
- dominant response is vasoconstriction (norepinepherine binding to alpha receptors)
Term
What is dual vasomostion mechanisms?
Definition
allows some dilation due to sympathetic
Term
If blood pressure drops, cardiac output will _______.
Definition
increase
Term
When will blood be needed the most in the skeletal muscles?
Definition
during exercise
Term
Why does heat storage exist?
Definition
because of an increase in work that causes temperature increase
Term
What determines how much heat is stored?
Definition
Hydration levels
Term
What will cause more heat storage, dehydration or being hydrated?
Definition
dehydration
Term
There is a _______ relationship between core temperature and dehydration.
Definition
linear
Term
What kind of sweating do eccrine sweat glands do?
Definition
thermal
Term
What is the autonomic innervation of eccrine sweat glands?
Definition
sympathetic (catecholemines and ACh)
Term
What structure difference makes appocrine sweat glands different from eccrine glands?
Definition
a hair follicle
Term
What are appocrine sweat glands associated with?
Definition
excreting oil, more odorous sweat
Term
Will appocrine glands be activated in the heat?
Definition
no
Term
Order of sweat leaving the body
Definition
water in capillaries --> sweat gland/coil --> duct --> pore --> skin surface
Term
How will we maintain plasma volume while sweating?
Definition
by taking water from intraceullular and interstitial spaces for the blood
Term
When ______ increases, the blood gets thicker.
Definition
hematocrit
Term
Acclimation
Definition
complex series of changes that occur in response to environmental changes from 7-14 days
Term
Acclimatization
Definition
slowly/naturally adapting to environmental changes
Term
Acclimatization in relation to heat
Definition
increased sweat rate with better distribution across the body
Term
How can we acclimatize ourselves faster?
Definition
exercising for 100 minutes 4-6 days in a row (more will not increase rate), acclimatized at intensity that you perform
Term
What are the physiological effects of exercising in the heat?
Definition
- increased blood flow
- increased ventilation
- sweating
- increase in body temperature
Term
What is the appropriate amount of body weight to lose from sweat when exercising?
Definition
8-11% (18-20% will kill us)
Term
How does a decrease in muscle blood flow affect activity?
Definition
decrease in oxygen and substrate delivery, also less efficient waste removal
Term
What is the main cause of fatigue?
Definition
heat cramps due to decreased blood flow
Term
What is stage 1 of heat exhaustion?
Definition
heat shock
Term
What can symptoms of heat illnesses be caused by?
Definition
the blowing off of too much CO2
Term
What happens at the level of the brain during heat stroke?
Definition
the hypothalamus loses ability to regulate temperature
Term
Why do people die from heat stroke?
Definition
a spike in temperature that stresses the myocardium
Term
What is hypovulemia?
Definition
decreased blood flow (blood viscosity can cause this)
Term
Partial pressure in lungs
Definition
H2O: 45 mmHg
O2: 105 mmHg
Term
What causes the oxyhemoglobin curve to shift left?
Definition
- decrease temperature
- decrease CO2
- increase pH
Term
What happens to hemoglobin's affinity to oxygen when the curve shifts to the left?
Definition
increases
Term
What causes the oxyhemoglobin curve to shift right?
Definition
- increase temperature
- increase CO2
- decrease pH
Term
What happens to hemoglobin's affinity to oxygen when the curve shifts to the right?
Definition
decreases
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