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Applied Exercise Physiology
Exam 4
359
Physiology
Undergraduate 4
11/26/2018

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Cards

Term
What are the two options for heat conservation in cold environments?
Definition
- increase heat production
- prevent heat dissipation
Term
What are the two types of cold environments?
Definition
water and air
Term
Cold Water
Definition
-lose body heat much faster (even if same temperature as the air)
- we will lose 6 degrees C of heat/hour in cold water
Term
Cold air environment factors
Definition
- moisture
- movement/wind chill
- duration of exposure
Term
What is the equation for heat loss?
Definition
kcals/m^2/hr
Term
What is m^2 in the hat loss equation?
Definition
our body's surface area/height
Term
What are the two types of insulation?
Definition
physiological and artificial
Term
Physiological insulation
Definition
- our shell
- determined by subcutaneous fat level and amount of vasoconstriction
Term
What does physiological insulation provide for the body?
Definition
provides a barrier between the core ad the environment
Term
Artificial insulation
Definition
clothing, blankets, etc.
Term
What makes up total insulation?
Definition
physiological shell + clothing + air trapped between the layers of clothing and the body
Term
What is our body's first response to cold?
Definition
vasoconstriction
Term
What does vasoconstriction do for our body?
Definition
it will decrease the gradient between the skin temperature and the environment and increase the insulation
Term
By how much will vasoconstriction reduce heat loss?
Definition
one sixth to one third
Term
What are the physiological responses to cold exposure?
Definition
- cutaneous vasoconstriction
- paradoxical increase in heart rate
- hyperpnea
- increased sympathetic activation
- increased electrical activity to skeletal muscle (shivering) --> NST, tVO_2
Term
Paradoxical increase in heart rate
Definition
- inexplicable
- increases blood pressure (both systolic and diastolic)
- increase peripheral resistance
- increase in catecholemines
Term
Hyperpnea
Definition
increase in pulmonic respiration/ventilation in rate and depth
Term
Increase in sympathetic activation
Definition
- norepinapherine from free nerve endings
- increased epinepherine from adrenal medulla
- activated in hypothalamus
- increases metabolic rate (increased thyroid hormones)
- increase in ACTH (adrenal corticotropic hormone)
- increased carb and fat metabolism
Term
Increased electrical activity to skeletal muscles
Definition
- shivering
- more delayed than the others
- varies from person to person
- amount of shivering is relative to the amount of insulation that a person has
- benefit is 3-4x increase in metabolic rate
Term
Non-shivering thermogenesis
Definition
- chemical heat production
- liver is an example
Term
tVO_2
Definition
- thermoregulatory oxygen consumption
- during exercise = oxygen cost from thermoneutral to cold environments
Term
Hunting effect
Definition
wave of vasodilation that occurs in response to extreme cooling (could preserve peripheral tissue)
Term
There will be a restriction of ______ blood flow even if vasoconstriction hasn't occur.
Definition
peripheral
Term
What happens to blood when it is closer to the surface and what can it cause?
Definition
it becomes more viscous which can cause turbulent flow (can cause restriction of flow)
Term
Vasoconstriction occurs in all anatomical parts of the body except the ________.
Definition
head
Term
Vasoconstriction will cause a _______ in heart rate.
Definition
decrease
Term
What happens when there is a decrease in heart rate?
Definition
there will be an increase in venous return and eventually metabolic rate
Term
The initial increase in metabolic rate happens concurrently with what type of heat conservation?
Definition
non-shivering thermogenesis
Term
What does vasoconstriction equal?
Definition
conservation
Term
What is the sympathetic mediation in heat conservation?
Definition
norepinepherine binding to alpha receptors
Term
Counter-current heat exchange
Definition
core to periphery and then reverse
Term
What is the main goal of shivering?
Definition
to produce heat
Term
What is heat production dependent on?
Definition
- skin receptors/temperature
- integrity of posterior hypothalamus
Term
What needs to be intact for shivering to occur?
Definition
Field of Forrell in the hypothalamus
Term
What will happen if shivering is allowed to happen long enough?
Definition
- skeletal muscle will increase and attempt to reach core temperature
Term
Shivering causes heat production at a ______ metabolic rate.
Definition
low
Term
Why do humans have less non-shivering thermogenesis than other animals?
Definition
because we have less brown fat
Term
What makes brown fat brown?
Definition
mitchondria
Term
Brown fat
Definition
- beta-receptor mediated
- particularly norepinepherine
- increase metabolic rate
- will produce heat
Term
Certain _____ can take white fat and have a browning effect.
Definition
hormones
Term
Brown fat in infants responds to _______.
Definition
epinepherine
Term
How can we maintain core temperature?
Definition
heat generation must exceed heat loss
Term
What effect does movement have on heat loss?
Definition
convective currents can cause faster heat dissipation
Term
Light exercise in cold
Definition
core temperature cannot be maintained
Term
Moderate to heavy exercise in cold
Definition
may promote enough heat generation to protect core temperature
Term
What physiological changes during exercise in the cold occurs?
Definition
less vasoconstriction and lower heart rate
Term
What are the two terms related to chronic cold exposures?
Definition
habituation and genetic adaptions
Term
Habituation
Definition
refers to responses to cold that occur due to the nervous system and are not induced physiologically to any other system
Term
Genetic adaptation
Definition
certain groups of people are genetically tolerant of chronically cold environments (not acclimatization)
Term
What factors affect our responses to the cold?
Definition
- skin fold thickness
- gender
- fitness level
Term
Skin fold thickness
Definition
tissue insulative value
Term
What is skin fold thickness dependent on?
Definition
vasoconstriction
Term
Gender
Definition
- cooler skin temperatures on females than males
- females have a greater insulative shell
Term
Males rely on heat _________________ and females on heat ______________.
Definition
production, conservation
Term
During exercise, people with ______ skin temperatures will lose _____ heat.
Definition
lower, less (lower gradient)
Term
What is the effect of the area/mass ratio during exercise?
Definition
more surface area means more diffusible area which means more heat will be lose (F have lower ratio)
Term
Fitness level
Definition
athletes have a core temperature that decreases to a lower point before shivering beings
Term
The insulative value is dependent on what factors?
Definition
- microenvironment
- thickness
- layers
- moisture
Term
Microenvironment
Definition
air in the area of the skin
Term
What is the CLO value?
Definition
rating of the insulative value of clothing
Term
Layers
Definition
add to heat conservation because of the air in the layers
Term
Thickness
Definition
a greater thickness allows for more artificial insulation
Term
Moisture
Definition
gained during exercise and too much insulation can cause this
Term
What happens when our insulation hold moisture (from sweat, rain, etc.)?
Definition
we dissipate heat 30% faster
Term
What are the most important things to insulate?
Definition
Head, hands, and feet
Term
Frostbite
Definition
caused by vasoconstriction and cooling of the tissue
Term
Second degree frostbite
Definition
increased likelihood of getting frostbite again, if it is deep enough then the tissues need to be amputated
Term
Wind chill
Definition
moving air does not change the temperature of the air, only removes heat from the body faster
Term
What happens if our clothing is not wind resistant?
Definition
the windchill will effect our insulative value
Term
What happens to cardiorespiratory endurance in cold environments?
Definition
- VO_2 maximum is reduced
- there is compromised unloading of O_2
- earlier fatigue onset
Term
Why is VO_2 maximum reduced when in cold environments?
Definition
because there is a reduction of maximal heart rate and cardiac output
Term
What happens to the oxyhemoglobin curve when in cold environments?
Definition
- O_2 unloading is compromised (tissues won't be oxygenated
- there will be a decrease in A_VO_2 difference
Term
Why is there an earlier fatigue onset when in cold environments?
Definition
- there will be extra energy needed to maintain the body's temperature (tVO_2)
- there is a compromised O_2 delivery due to blood cooling
- blood cooling increases viscosity
Term
What do cold environments do to our strength and power?
Definition
- decreased peak torque and force production
- biochemical alterations
Term
How are peak torque and force production affected by cold environments?
Definition
- slower cross-bridging occurs (BBBB)
- sarcoplasmic gel will increase in viscosity (movement of Ca will slow)
- enzyme activity slows
- won't effect deeper muscles
Term
What happens to muscular endurance in cold environments?
Definition
- enhanced by slight cooling (helps with heat dissipation)
- compromised by severe cold (27 degrees C, neural conduction compromised below this)
Term
What is barometric pressure?
Definition
air columns pushing down on us (lower pressure means there's a bigger column of air)
Term
In lower barometric pressures, oxygen ________ drops, but oxygen __________ will stay the same.
Definition
concentration, partial pressure
Term
The air will get ______ and _____ with elevation.
Definition
colder (1 degree C for every 150 meters), drier (decrease in water vapor pressure
Term
What happens to solar radiation with an increase in elevation?
Definition
- there is an increase (because there is a decrease in moisture)
- snow also increases the reflection of the UV rays
Term
Why is cloud cover significant in altitude?
Definition
- being higher than the clouds
- air-pollution (either way)
Term
What are all cardiorespiratory responses due to altitude change relative to?
Definition
a decrease in PO_2
Term
What will changes in the ambient air be reflected in?
Definition
the arterial system
Term
What is the pressure of blood at sea level vs. 4,300 m?
Definition
760 vs 460 mmHg
Term
What is the diffusion gradient at sea level vs. 4,300 m?
Definition
60 vs 15 mmHg
Term
What is the driving force to breathing changes?
Definition
- drop in alveolar gas because of drop in PO_2 levels (need to moisturize)
- peripheral chemo-receptors are more sensitive to oxygen changes and will take over
Term
Why does our rate, depth, and rhythm of breathing change at different altitudes?
Definition
in an attempt to bring alveolar PO_2 up again
Term
Hyperventilation
Definition
faster breathing rate
Term
Cheyne-Stokes breathing
Definition
- symptomatic rhythym of breathing
- three deep breaths in and then pause
- may happen right before someone dies
Term
When is Cheyne-Stokes breathing more dramatic?
Definition
- when someone isn't used to the altitude
- when it's cold
Term
Reduction in breathing movement
Definition
less contribution of the diaphragm
Term
Tidal volume changes
Definition
increasing tidal volume too much will cause us to blow off too much CO_2 (seen by too much H+ in the blood)
Term
Respiratory alkalosis
Definition
an decrease in H+ concentration of the blood (more basic)
Term
Increasing the pH will move the oxyhemoglobin dissociation curve to the _____.
Definition
left
Term
What happens when respiratory alkalosis occurs?
Definition
our kidneys will filter our bicarbonate to buffer the bases (equivalent of adding H+) and urine output will increase (leads to dehydration and cardiovascular changes)
Term
What are some cardiovascular changes that can occur?
Definition
- resting heart rate increases
- max heart rate decreases
- heart rate at any submaximal exercise intensity increases
Term
Why does the the resting heart rate increase at higher altitudes?
Definition
the O_2 volume is decreased so the blood must pump faster to get blood to where it needs to go
Term
Why does the maximum heart rate decrease at higher altitudes?
Definition
because of dramatic water losses and plasma volume decrease (up to 25%)
Term
What happens when our plasma volume decreases?
Definition
- change in circulating blood volume
- hematocrit will go up (increases blood viscosity, heart works harder)
Term
What happens when at submaximal exercise intensity?
Definition
- there will be less fluid in the tubes
- blood pressure will drop
- heart rate will increase
Term
When the oxyhemoglobin curve moves to the right due to alkalosis, what happens to oxygen?
Definition
- compromised loading at the level of the tissues - help with binding at already low PO_2 levels
Term
There will be a ________ in maximal oxygen consumption with exposure to higher altitudes.
Definition
decrease
Term
Why is there a decrease in max heart rate and stroke volume?
Definition
because of a decrease in venous and arterial PO_2 (tension)
Term
How much blood is flowing through the tissues?
Definition
- related to cardiac output and number of open capillary beds at the muscular level
- more muscle activity means more blood flow
Term
What is the tissue oxygen level/what is the gradient for exchange?
Definition
- lower oxygen in tissue means wider gradient
- based on how hard our muscles are working
Term
If we _______ our diffusible distance and _________ our diffusible surface area, what happens?
Definition
- decrease, increase
- helps to increase extraction of O_2 from the blood due to hemoglobin not being saturated enough
Term
What are changes in hematocrit based on?
Definition
loss of plasma
Term
What does a change in hematocrit do?
Definition
- increases the work it takes to move the blood
- increases the oxygen carrying capacity of the blood
Term
What does an increase in the uptake in iron of bone marrow allow?
Definition
- more hemoglobin uptake
- O_2 carrying capacity increases
- blood volume, heart rate, and cardiac output will return to normal
Term
What can help to decrease the acute physiological effects of altitude?
Definition
forced hydration (3-4 L daily)
Term
Body weight changes due to altitude
Definition
- dehydration, lack of desire to eat
- loss of muscle (protein wasting)
Term
Acclimation/acclimatization adaptations
Definition
- can improve ability to perform
- do not sufficiently return to performance of sea level
Term
Why does O_2 carrying capacity increase?
Definition
due to an increase in red blood cell production
Term
What does erythropoirtin (EPO) cause?
Definition
blood volume expansion (for about 3-4 months)
Term
When is erythropoirtin secreted in higher concentrations?
Definition
in the first 2-3 days following exposure to higher altitudes
Term
What does an increase in erythropoietin (EPO) cause in the body?
Definition
it triggers the formation of red blood cells
Term
When erythropoietin (EPO) triggers the formation of red blood cell, what happens?
Definition
blood volume expansion (3-4 months)
Term
What is polycythemia?
Definition
- an increase in RBC concentrations in the blood which causes an increase in hematocrit
- caused by an increase in EPO
Term
What happens in an acute adjustment of hematocrit?
Definition
the plasma volume increases
Term
If the O_2 carrying capacity increases, what can run more smoothly?
Definition
stroke volume and cardiac output
Term
What does muscle structure and function have to do with acclimation at altitudes?
Definition
- decreased CSA
- increased capillary density
Term
When CSA is decreased in muscle, what happens?
Definition
- decreased demand for oxygen
- decreased performance
Term
What happens to our muscle metabolic potential when at high altitudes?
Definition
- muscle will try to preserve oxidative capacity
- blood volume changes
Term
What happens when muscles try to preserve their oxidative capacity?
Definition
the muscle will change because of lower oxygen tension, decreases performance
Term
Why can blood volume changes be positive at altitudes higher?
Definition
because there is an increase in hemoglobin
Term
What happens when there is less oxygen present?
Definition
we lose the gradient for exchange, performance will be hurt
Term
What kind of athletes are better off adjusting to altitude?
Definition
- more aerobically trained (non-oxidative capacity)
Term
What are the detrimental effects of training at high altitudes?
Definition
- hypoxia
- smaller training stimulus
- dehydration
- low blood volume
- low muscle mass
- lower intensity of training
Term
What is the best way to train when living at high levels?
Definition
live high, train low (no hypoxic stress)
Term
What are strategies for competing at altitudes?
Definition
- compete ASAP
- train for two weeks (worst is over)
Term
What affects the onset of acute mountain sickness?
Definition
- the person
- the level of the altitude
- how fast altitude was reached
Term
At what altitude do initial symptoms occur?
Definition
200 and 3600 meters
Term
What are the physiological effects of acute mountain sickness?
Definition
- nausea
- decreased urine output
- decreased appetite
- light headed-ness
Term
What are the psychological effects of acute mountain sickness?
Definition
- increased sensitivity of oxygen deprivation in the nervous system (body is trying to let you know you don't have enough oxygen)
- personality changes
- mental and motor deficits
- slowed speech
- distorted thinking
- impaired decision making
Term
What affects the level of impairment that occurs with acute mountain sickness?
Definition
- level of hypoxia
- how complex the task is
- how familiar that person is with the task
- function will improve over time but will not reach normal level
Term
HAPE
Definition
high altitude pulmonary edema
Term
HACE
Definition
high altitude cerebral edema
Term
What is the go to unit to measure energy?
Definition
kcal
Term
Calorimetry
Definition
measuring heat
Term
Direct calorimetry
Definition
measuring the amount of heat
Term
What is the only was we can truly measure direct calorimetry?
Definition
closed off room wit oxygen supply and cooling system
Term
What is direct calorimetry actually most effective in measuring?
Definition
resting measurements rather than exercise because effects of sweat and evaporation will affect the measurements
Term
Indirect calorimetry
Definition
measures respiratory gas exchage
Term
Why may indirect calorimetry have bad measurements?
Definition
- tends to only be accurate for steady state oxidative metabolism
- rapid fluctuation cannot be measured, nor anaerobic contributions
Term
How do we measure energy expenditure/indirect calorimetry?
Definition
with a spirometer
Term
What does a spirometer measure?
Definition
the concentrations of O_2 and CO_2 of the expired gas
Term
What does RER stand for?
Definition
respiratory exchange ratio
Term
What is the RER?
Definition
ratio of CO_2 exhaled over O_2 inhaled (how much CO_2 is created for the amount of O_2 inhaled)
Term
What is the RER an estimation of?
Definition
what is happening in the skeletal muscles
Term
What does RQ stand for?
Definition
respiratory quotient
Term
What is the RQ estimating?
Definition
RER at the level of the skeletal muscles
Term
What can we use RER for?
Definition
- the use of carbohydrates and fats as substrates
- how many kcals we are expending
- O_2 efficiency
Term
What is the typical range for the RER?
Definition
.7 to 1.0
Term
When the RER is one or more what is being used as fuel?
Definition
carbohydrates
Term
When is RER higher?
Definition
at higher intensities of exercise
Term
When the RER is .7 or less what is being used as fuel?
Definition
fats
Term
Our energy expenditure will typically be less efficient with a ________ RER.
Definition
higher
Term
What is the RER for one molecule of glucose?
Definition
1
Term
What is the RER for one molecule of palmitic acid?
Definition
.7
Term
What happens to the RER when gluconeogenesis occurs?
Definition
it will be below .7
Term
What is the metabolic rate?
Definition
rate that our body uses energy
Term
What is the typical resting RER value?
Definition
.8
Term
What is the metabolic rate based upon?
Definition
whole body O_2 consumption and caloric equivalent
Term
What is the volume of oxygen at rest?
Definition
about .3 L/min
Term
What is the caloric equivalent?
Definition
about 2000 kcal/day
Term
What is basal metabolic rate?
Definition
- BMR
- the minimum energy requirement for living
Term
Why is it hard to get an accurate BMR?
Definition
because at any onetime we have other stimuli affecting that rate
Term
What are the strict conditions for testing BMR?
Definition
- supine
- thermoneutral environment
- after 8 hours of sleep
- after 12 hours of fasting
- dimly lit/dark room
Term
What is the BMR affected by?
Definition
- fat free mass (FFM)
- body surface area (BSA)
- age
- stress
- hormones
- body temperature
Term
The more fat free mass, the _______ the BMR.
Definition
higher
Term
The more body surface area, the _______ the BMR.
Definition
higher
Term
What happens to BMR with age?
Definition
speeds up in adolescents, slows down following age 25
Term
What is an example of a hormone that increases the BMR?
Definition
thyroxine
Term
The higher the temperature, the ______ the BMR.
Definition
lower
Term
What does RMR stand for?
Definition
resting metabolic rate
Term
How close to BMR is and how many calories are in RMR?
Definition
- within 5-10%
- 1200-2400 kcals/day
Term
What is our total daily energy expenditure?
Definition
- includes all activity
- 1800-3000 kcal daily
Term
What are the three component of total daily expenditure?
Definition
- BMR
- energy used for digestion
- activity
Term
What is the most volatile component of daily energy expenditure?
Definition
activity
Term
VO_2 kinetics
Definition
a show of change in oxygen consumption
Term
Steady state
Definition
oxygen consumption matching our level of activity
Term
Things that change our VO_2 kinetics
Definition
- slow component
- steady state
- VO_2 drift
Term
Slow component
Definition
ability to reach steady state as we exercise
Term
What happens after a certain intensity is reached?
Definition
it will be tough to achieve steady state
Term
What is one reason we may not achieve steady state anymore?
Definition
recruitment of type II fibers
Term
What happens when we start recruiting type II fibers>
Definition
we reach lactate threshold
Term
There (is/is not) a linear relationship between VO_2 and exercise intensity.
Definition
is NOT
Term
VO_2 drift
Definition
after we reach steady state and keep exercising, VO_2 max can increase for that continued intensity
Term
VO_2 max as a measuremet
Definition
- best single measurement of oxidative fitness
- not good indicator of performance
Term
What is VO_2 max?
Definition
how much oxygen is being consumed at the body's peak ability to consume oxygen
Term
What is VO_2 max least important in?
Definition
team sports
Term
Can VO_2 max be improved with training?
Definition
yes
Term
When will VO_2 max plateau?
Definition
after about 8-12 weeks of training
Term
About how much can people improve their VO_2 max by?
Definition
20%
Term
A trained individual has the capacity to __________.
Definition
increase stroke volume
Term
Why is stroke volume increased in trained individuals?
Definition
because of
- increased plasma volume
- increase in mitochondrial density
- increase in capillary density
- increase in oxygen extraction
- increased diffusible surface area ad distance
Term
Absolute VO_2 max
Definition
liters of O_2/minute
Term
What allows variation in absolute VO_2 max?
Definition
- body size
- weight bearing activities (more appropriate for NWB)
Term
What does absolute VO_2 max tell us about physical fitness?
Definition
not much
Term
Normalized VO_2 max
Definition
milliliters of O_2 per kilogram of body weight per minute
Term
What VO_2 max should be used for weight bearing activities?
Definition
normalized
Term
Heavier people will have a higher _____ VO_2 max, but _____ VO_2 max will be the same.
Definition
absolute, normalized
Term
What happens when we veer away from steady state?
Definition
there will be changes in metabolic rate
Term
Anaerobic Energy Expenditure Curve
Definition
delay on O_2 consumption from sitting to standing and visa versa
Term
O_2 deficit
Definition
from start of exercise until O_2 requirement is reached
Term
Higher changes in activity, have ______ O_2 deficits.
Definition
higher
Term
What happens when there is an O_2 deficit?
Definition
- changes in ATP:ADP ratio
- changes in CrP:Cr ratio
- start using carbs so glycolysis will occur
- cytoslic NAD:NADH ratio increases until system matches it
Term
The steady state _____ the changes in metabolic rate.
Definition
matches
Term
Excess post-exercise oxygen consumption
Definition
- EPOC
- demand is low but levels stay high
Term
Why do O_2 levels remain high for EPOC?
Definition
- to replenish CrP and ATP levels (bring ratios back)
- to buffer lactate/lactic acid
- muscle returns to normal temperature andpH
Term
Why do we warm up before exercising?
Definition
to keep the amount that we exercise at its peak
Term
We can never reach _______ after we reach the _________.
Definition
steady state, lactate threshold
Term
Once the lactate threshold is reached, what do we use for energy?
Definition
- carbs
- anaerobic
Term
What is the lactate threshold a good indicator of?
Definition
potential for endurance exercise
Term
Lactate production may exceed lactate _____.
Definition
clearance
Term
Higher exercise intensity produces more ______.
Definition
lactate
Term
What is a better indicator of performance than VO_2 max?
Definition
the lactate threshold
Term
What is the lactate threshold expressed as?
Definition
a percentage of VO_2 max
Term
Movement economy
Definition
how efficient our movement is
Term
What is movement economy achieved by?
Definition
through practice, coordination and muscular components (more skill)
Term
When is movement economy at its highest?
Definition
when there are no wasted movements
Term
People who are more fit have a ______ lactate threshold.
Definition
higher
Term
Factors effecting movement economy
Definition
-race distance
- practice
- varies with type of exercise
Term
Race distance
Definition
the longer the race the higher the movement economy will be
Term
Practice/entrainment
Definition
- repetitive movements
- changes in breathing and heart rates
- will match the movements of the body
Term
Type of exercise
Definition
runners vs. swimmers (swimmers must move with the most efficient patterns)
Term
Successful endurance performance depends on
Definition
- VO_2 max
- lactate threshold
- economy of effort
- type I muscle fiber percentage
Term
Untrained individuals his their lactate threshold at ______ of max while trained individuals hit it at ______ and elite at _____.
Definition
60-70%, 70-75%, 80-85%
Term
Economy of effort
Definition
good movement efficiency
Term
What is more beneficial for muscle performance, higher or lower type I fiber percentage?
Definition
higher
Term
Energy cost variables
Definition
- type
- intensity
- calculated from VO_2
- calculations ignore anaerobic aspects
Term
When is energy cost best estimated?
Definition
With rhythmic activities
Term
In higher intensity training, ______ is higher.
Definition
EPOC
Term
What is fatigue?
Definition
- decrements of muscular performance with continued effort accompanied by sensations of tiredness
- inability to maintain required power output to continue muscular work at that intensity
Term
What can also cause the effects of fatigue?
Definition
injury
Term
What is the key aspect of fatigue?
Definition
that it is completely reversible with rest
Term
Complex phenomenon factors
Definition
- exercise
- muscle fiber type
- training status, diet
Term
Complex phenomenon definition
Definition
there can be a limit on any exercise due to anything (environment, intensity, injury, fatigue, etc)
Term
Synergistic effects
Definition
contribute to each other
Term
Central vs. peripheral causes of fatigue
Definition
- originating from motor cortex/CNS (central)
- within muscle itself (peripheral)
Term
Major loci/causes
Definition
- systemic
- muscle
- nerve conduction/CNS
Term
Systemic
Definition
energy delivery to body's systems
Term
Muscle
Definition
- metabolism
- accumulation of by-products
- failure of contractile mechanisms
Term
Muscle - metabolism
Definition
there is not adequate metabolism at the level of the muscle because of substrate availability
Term
Muscle - accumulation of by-products
Definition
- H+ ions (pH increase)
- inorganic phosphates
Term
Muscle - failure of contractile mechanisms
Definition
- related to Ca+ release from the sarcoplasmic reticulum
- changes in Ca+ concentration
Term
Nerve conduction/CNS
Definition
altered neural control of muscle contraction
Term
Where do the action potentials occur?
Definition
in the neuromuscular junction
Term
What do we need for the motor potentials?
Definition
need ACh which crosses the cleft and binds to muscurinic receptors
Term
What happens when ACh binds to muscurinic receptors?
Definition
it is broken down and recycled into fiber, then ACh is released
Term
CNS control of muscle contraction
Definition
when fatigued do we lose our ability to activate motor neurons at the level of the cortex?
Term
CrP depletion
Definition
- CrP is sacrificed so that ATP is not
- caused by inorganic phosphate molecule accumulation
Term
What can pacing ourselves help us do?
Definition
keep our ATP, and therefore our CRP, levels constant
Term
Glycogen depletion
Definition
carbs are depleted quickly within the first few moments of exercise (more with higher intensity)
Term
Effect of intensity on glycogen
Definition
more rapidly with higher intensity
Term
Effect of time on glycogen
Definition
most happens right away and then it slows down as time progresses
Term
What are recruitment patterns of fiber types?
Definition
the most and most frequently recruited based on intensity
Term
_______ intensity activity will be much more depleting of Type I fibers.
Definition
lower
Term
_______ intensity activity will be much more depleting of Type II fibers.
Definition
higher
Term
What muscle fiber type is recruited sooner/more frequently?
Definition
Type I
Term
Why does the ATP:ADP ratio decrease?
Definition
because ADP will increase rather than ATP being depleted
Term
What muscles are recruited the earliest, longest, and are most vulnerable to fatigue?
Definition
muscles that are considered activity specific
Term
What happens when muscle glycogen is not enough to sustain muscles during exercise?
Definition
we will pull glucose from the blood
Term
When we use glucose from the blood during exercise, what happens?
Definition
liver will increase glycogen breakdown
Term
Fatigue onset and muscle glycogen depletion are ____________.
Definition
directly proportional
Term
What is glycogen used for?
Definition
to provide NADH for the electron transport chain
Term
What is the end product of glycolysis?
Definition
pyruvate
Term
What is used to replenish acetyl coenzyme A?
Definition
pyruvate
Term
What does acetyl coenzyme A feed into?
Definition
the Krebs cycle
Term
______ slows down the oxidative system.
Definition
fatigue
Term
What is required to maintain muscle function?
Definition
muscle glucogenolysis
Term
With the absence of glycogen, what needs to compensate?
Definition
free fatty acid metabolism
Term
What happens when fats are oxidized?
Definition
it is too slow so there will be a reduction in capacity to work at a given intensity
Term
What are the metabolic by-products of fatigue?
Definition
- inorganic phosphates
- heat
- H+ ions
- lactate
Term
What causes the metabolic by-products to be released?
Definition
when ATP is used
Term
What role does inorganic phosphate play a role in?
Definition
- comes from CrP that replenish ATP
- stimulates glycogen use during high intensity exercise
- used for fuel for the heart and respiratory muscles
- cant be used to make a new glucose in the liver
Term
What is produced during high intensity exercise to help us prolong activity?
Definition
lactate
Term
What does heat that is retained by the body do?
Definition
- increase our core temperature (alter metabolic rate)
- increase our carbohydrate use
Term
How do we dissipate heat from the body?
Definition
by increasing blood circulation and competing with muscles to reduce blood flow
Term
When muscles work more non-oxidatively, what happens?
Definition
glycogen increases
Term
What happens with the increase in glycogen use?
Definition
- decrease in pH
Term
What does heat do in relation to fatigue?
Definition
decreases the time until
Term
What is the optimal muscle temperature for prolonging the onset of fatigue?
Definition
51 degrees F
Term
Lactate as a metabolic by-product
Definition
- accumulates during brief high intensity exercise
- pH will decrease (increase in H+ ions)
Term
What do buffers do within a muscle?
Definition
help us prevent harmful effects of acidity (below a pH of two will kill our muscles)
Term
What can a pH below 6.9 cause?
Definition
inhibits processes such as glycolysis and ATP synthesis
Term
What can a pH below 6.4 cause?
Definition
prevents glycogen breakdown
Term
What are neural factors affecting fatigue?
Definition
- substrate depletion
- accumulation of by-products
Term
What can repetitive stimulation of nerves in skeletal muscles cause?
Definition
fatigue at the level of the neuromuscular junction
Term
In the neuromuscular junctions, what is released into the cleft and then bound and broken down?
Definition
acetylcholine
Term
What receptors does acetylcholine bind to?
Definition
the enzyme cholinesterase
Term
When there is a release of ACh at a high rate what happens?
Definition
fatigue
Term
When there are delays in ACh synthesis and release (amount and rate), what happens?
Definition
the muscle may not fire because there is not enough ACh to reach threshold
Term
What can cause an increase in threshold level for muscle contraction?
Definition
repetitive stimulation on the post-synaptic side
Term
What affect foes the neuromuscular junction have on SR and calcium release?
Definition
they are decreased
Term
How are SR and calcium related?
Definition
calcium is released by the SR
Term
What happens when there is less calcium?
Definition
there will be less in the cytosol to bind to troponin
Term
What happens when troponin activates tropomyosin?
Definition
a decrease in excitation contraction coupling
Term
What happens when there is stress on muscle fiber recruitment?
Definition
- fight or flight
- muscle is hyper acute
- threshold for stimulation is changed
- more circulation of catecholamines --> increase in carbohydrates --> increase in metabolic rate (can contribute to fatigue)
Term
Skeletal muscle movement is voluntary so we will have a _______ and _______ influence.
Definition
conscious and subconscious
Term
Exercise tolerance
Definition
can push through fatigue mentally despite what is happening physiologically
Term
Effects of training on exercise tolerance
Definition
- elite athletes can endure more pain and tolerate more discomfort related to fatigue
Term
Strength
Definition
amount of force that a muscle can generate
Term
Dynamic strength
Definition
varies by speed and joint angle, concentric contraction, and length-tension relationship
Term
Static strength
Definition
isometric exercises
Term
How do we measure maximal strength?
Definition
1 rep max
Term
Muscular power
Definition
- speed involved with force being produced
- explosiveness
- (force*distance)/time
Term
What are examples of power exercises?
Definition
vertical or long jumps, sprints
Term
Muscular endurance
Definition
capacity to endure repeated contractions or a single contraction over time while resisting fatigue
Term
What does AMRAP stand for?
Definition
as many reps as possible
Term
Aerobic power
Definition
rate of energy release by oxygen metabolic processes (rate of oxidative metabolism)
Term
What is maximal aerobic power?
Definition
- max capacity of oxidative metabolism
- rate of ATP replenishment
- max VO_2
- max oxygen consumption
Term
How is maximal aerobic power tested?
Definition
- indirect calorimetry
- validated field tests
Term
Anaerobic power
Definition
- relates to rate of energy release through non-oxidatve means
- replenish ATP
- anaerobic capacity
Term
Wingate test
Definition
- bike for 30 seconds as hard as you can, 30 second break
- start without resistance and then add
- measure first five seconds of the 30 seconds to measure power
Term
General principles of training
Definition
- individuality
- specificity
- reversibility
- overload
- variation
- training variables
Term
Individuality
Definition
- genetics alter performance
- responses and adaptions
- growth rate
- cell metabolism
- muscle fiber type distribution
- cardio-respiratory variation
Term
High vs low responders
Definition
high capacity to respond to exercise changes
Term
Specificity
Definition
adaptation and responses that we get from exercise are related to the type of stress
Term
Training adaptations are highly specific to ____________, ________________, and ______________.
Definition
activity, volume, intensity
Term
SAID principle
Definition
specific adaptation to imposed demands
Term
Reversibility
Definition
- use it or lose it
Term
Variation/Periodization
Definition
- changes in training goals over time
- works best with individual sports who compete infrequently
Term
What are the three components of periodization?
Definition
macrocycles, mesocycles, and microcycles
Term
Macrocycles
Definition
long term goals (weeks-months)
Term
Mesocycles
Definition
- division of macrocycle
- week to month again
- how often you vary the training
Term
Microcycles
Definition
- division of mesocycle
- individual training week or workout
Term
What are the four training variables?
Definition
- frequency
- intensity
- time
- type
Term
What must happen to training variables to achieve our desired dose of training stress?
Definition
must be varied and progressed
Term
Frequency
Definition
how many days or sessions per week
Term
Intensity
Definition
- how much of a given load
- how hard you are working
Term
Time
Definition
how long (inversely proportional to intensity)
Term
Type
Definition
what activity is being performed
Term
What is the stressor of an optimal dose/response?
Definition
exercise
Term
What training outcomes can there be?
Definition
- improvement
- none
- backward
Term
When will we see the outcomes of training?
Definition
6-10 weeks (intensity, volume)
Term
Rate of adaptation
Definition
genetically limited
Term
What can too much training lead to?
Definition
- decrease in performance
- increased risk of injuries
Term
When balancing a workout load, what three things are needed for safe/healthy progress?
Definition
volume, intensity, and rest
Term
Overtraining
Definition
too much of a stimulus that leads to chronic fatigue and increased risk of illness (overuse injuries, OTS)
Term
Acute overload
Definition
- progressive overload
- stress that causes positive physiological adaptations
- improvements in performance
Term
Undertraining
Definition
- minor physiological adaptations
- no performance improvements
- can be intentional for rest or before competition
Term
Taper
Definition
prior to competition, intentional undertraining
Term
Over training
Definition
- won't get optimal benefits
- maladaptations
- performance decriments
- OTS
Term
Over reaching
Definition
- pushing close to physiological limits
- there are planned, systemic attempts
- short duration of high intensity/volume
Term
In some sports using ______ the volume will increase the benefits and decrease the risks.
Definition
one-half
Term
Volume and intensity should be ______ when planning workouts
Definition
indirectly proportional
Term
Over training syndrome
Definition
- unexplained drop in performance or function that can persist for weeks-years
- duration depends on over training duration and extent of maladaptations
- cannot be remedied by short periods of rest
- can cause phys/psych stresses
Term
Signs/Symptoms of OTS
Definition
- decreased strength
- decrease in coordination
- decrease in capacity for exercise
- increased levels of fatigue
- changes in appetite
- weight loss due to msucle wasting
- sleep and mood disturbances
- lack of motivation
- lack of vigor
- loss of concentration
- dpression
Term
Contributing factors of OTS
Definition
- excessive stress
- psychological factors
- stress of anticipated competition
- emotional stresses of competitions
Term
_________that happens during training is not over training.
Definition
fatigue
Term
Sympathetic effects
Definition
speeds things up
Term
In autonomic response to over training, what will be hyperactivated?
Definition
both the sympathetic and parasympathetic NS
Term
Exposure to sympathetic
Definition
- increased blood pressure
- loss of appetite
- sleep and emotional disturbances
- increase in metabolic activity (high stress)
Term
Exposure to parasympathetic
Definition
- increased fatigue
- decreased resting heart rate
- decreased resting VP
- rapid heart rate
- norepinepherine from adrenal medulla
Term
What will assist in endocrine function?
Definition
catecholamines (adrenal cortex)
Term
In relation to cortisol and testosterone which is better for muscular adaptation to exercise?
Definition
testosterone (cortisol binds to test and inhibits it)
Term
Changes in the testosterone:cortisol ratio can indicate ______ synthesis in the body.
Definition
protein (high = synthesis favored, low = protein breakdown)
Term
Immune system in relation to over training
Definition
- suppression
- light-moderate enhances
- excessive training decreases
- higher risk of infection & illnes
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