Term
| Active Artificial Immunity |
|
Definition
| acquired from vaccination |
|
|
Term
|
Definition
| acquired by fetuses from passage of IgG antibodies across the placenta |
|
|
Term
|
Definition
|
|
Term
|
Definition
| acquired by infusion of antibodies taken from another person or animal |
|
|
Term
|
Definition
weakened microbes
should not cause disease
generate strong immune response
lifelong immunity
ie: measles, chicken pox |
|
|
Term
| Inactivated Whole Agent Vaccine |
|
Definition
pathogen is killed
produces weaker immune response
booster shots needed
safer than attenuated
ie: influenza |
|
|
Term
|
Definition
inactivated toxin
ie: tetanus |
|
|
Term
|
Definition
contains only parts of a pathogen
made through recombinant DNA technology
ie: hepatitis B |
|
|
Term
|
Definition
carrier protein attached to antigen
used when antigen alone doesn't cause strong enough immune response
ie: HIB (haemophilus influenza type b) |
|
|
Term
| DNA (Nucleus Acid) Vaccine |
|
Definition
a plasmid used as a vaccine
currently approved for use in animals
ie: west nile virus for horses |
|
|
Term
|
Definition
| the study of blood serum and its constituents and their role in protecting the body from disease. Specifically, antigen-antibody interactions |
|
|
Term
| Monoclonal Antibodies (Mabs) |
|
Definition
derived from B-cell hybridoma clone
identical
highly specific
produced in large quantities |
|
|
Term
| Monoclonal Antibody Application |
|
Definition
identify the presence of bacterial pathogens
indicate the presence of hormones
ie: urine pregnancy test |
|
|
Term
|
Definition
reaction of soluble antigens with IgG or IgM antibodies
form large, interlocking aggregates called lattices
only occur when antigen/antibody ratio is optimal |
|
|
Term
| Precipitation Reaction Application |
|
Definition
blood specimen mixed with test antigen
detects antibodies or antigens in specimen
low sensitivity
used to detect fungal infection |
|
|
Term
|
Definition
involves large particles or cells that carry antigenic molecules
low sensitivity |
|
|
Term
| Agglutination Reaction Application |
|
Definition
Direct-serum antibody titer
Indirect-rapid detection of antibodies
Hemagglutination-Blood typing |
|
|
Term
|
Definition
| antibodies directed against toxins can be produced in animals then injected into humans to provide passive immunity |
|
|
Term
| Neutralization Reaction Application |
|
Definition
| detect presence of anti-viral antibodies |
|
|
Term
| Direct Fluorescent Antibody testing |
|
Definition
dye linked to known antibody
used to detect the presence of a specific pathogen |
|
|
Term
| Indirect Fluorescent Antibody testing |
|
Definition
| dye linked to antibodies specific for human antibodies |
|
|
